Prefest Oral Tablet 1-0.09Mg Drug Medication Dosage Information
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Prefest: Oral tablet (1-0.09mg)

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What is this Medicine?

ESTRADIOL; NORGESTIMATE (es tra DYE ole; nor JES ti mate) is used as hormone replacement in menopausal women who still have their uterus. This product is used to treat hot flashes and prevent osteoporosis.

CVS Pharmacy Patient Statistics for Prefest: Oral tablet(1-0.09mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
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Prefest Tablet

NDC: 512850063
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Menopause, Hot Flashes, Osteoporosis Prophylaxis, Atrophic Vaginitis

Storage Information
Store at controlled room temperature (between 68 and 77 degrees F)
Prefest Tablet

Reported Side Effects for Prefest Tablet

Endometrial Hyperplasia Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Depression Incidence:
5.0%*
Severity: MODERATE
Onset: DELAYED
Gas Incidence:
5.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
5.0%*
Severity: MILD
Onset: EARLY
Muscle Pain Incidence:
5.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
6.0%*
Severity: MILD
Onset: EARLY
Vaginal Infection Incidence:
7.0%*
Severity: MODERATE
Onset: DELAYED
Menstrual Cramps Incidence:
8.0%*
Severity: MILD
Onset: DELAYED
Joint Pain Incidence:
9.0%*
Severity: MILD
Onset: DELAYED
Breakthrough Bleeding Incidence:
>10.0%*
Severity: MILD
Onset: DELAYED
Stomach Pain Incidence:
12.0%*
Severity: MILD
Onset: EARLY
Breast Pain Incidence:
16.0%*
Severity: MILD
Onset: DELAYED
Headache Incidence:
23.0%*
Severity: MILD
Onset: EARLY
No Menstrual Periods Incidence:
51.0%*
Severity: MILD
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Prefest Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Minor Lifestyle Interaction
Grapefruit juice and Prefest Tablet(Estradiol)
Grapefruit juice and Estrogens(Estradiol)
Grapefruit juice and grapefruit-containing foods may increase the side effects of estrogen in some females, such as nausea, breast tenderness, headache or fluid retention. There may be no interaction. Do not significantly change your grapefruit intake while taking estrogens for hormone replacement therapy or as part of hormonal birth control products. Report any unusual side effects, like unusual non-menstrual vaginal bleeding, promptly for evaluation.
Pregnancy & Lactation Information
FIRST Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

SECOND Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

THIRD Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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Patient Experiences with Prefest

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