Premarin Lyophilisate For Solution For Injection 25Mg Drug Medication Dosage Information
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Premarin: Lyophilisate for solution for injection (25mg)

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What is this Medicine?

CONJUGATED ESTROGENS (CON ju gate ed ESS troe jenz) is a mixture of female hormones. It is used to treat abnormal bleeding from the uterus caused by a hormonal imbalance. This medicine may also be used for a short period of time to increase your body's estrogen levels.

In-Depth Information

Premarin 25mg Powder for Injection

NDC: 000460749
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Dysfunctional Uterine Bleeding

Storage Information
Store unopened containers in refrigerator (36 to 46 degrees F)
Store reconstituted product in accordance with package insert instructions
Premarin 25mg Powder for Injection

Reported Side Effects for Premarin 25mg Powder for Injection

Blockage Of Bile Duct Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Liver Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Yellow Skin Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Vomiting Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Weight Gain Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Elevated Hepatic Enzymes Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Emotional Lability Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Fluid Retention Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Injection Site Reaction Incidence:
<5.0%*
Severity: MILD
Onset: RAPID
Skin Rash Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Blood Clot In Eye Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Cholecystitis Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Gallstones Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Loose Stools Incidence:
<7.0%*
Severity: MILD
Onset: EARLY
Swelling Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Erythema Multiforme Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
High Blood Pressure Incidence:
<5.0%*
Severity: MODERATE
Onset: EARLY
High Triglycerides Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Breast Pain Incidence:
<14.0%*
Severity: MILD
Onset: DELAYED
Itching Incidence:
<5.0%*
Severity: MILD
Onset: RAPID
Hives Incidence:
<5.0%*
Severity: MILD
Onset: RAPID
Stomach Pain Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
1.0-7.0%*
Severity: MILD
Onset: EARLY
Menstrual Cramps Incidence:
1.0-8.0%*
Severity: MILD
Onset: DELAYED
Endometrial Hyperplasia Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Tired Incidence:
1.4-8.0%*
Severity: MILD
Onset: EARLY
Inability To Sleep Incidence:
2.9-7.0%*
Severity: MILD
Onset: EARLY
Muscle Cramps Incidence:
3.0-7.0%*
Severity: MILD
Onset: DELAYED
Peripheral Vasodilation Incidence:
3.0-5.0%*
Severity: MODERATE
Onset: RAPID
Joint Pain Incidence:
3.5-14.0%*
Severity: MILD
Onset: DELAYED
Headache Incidence:
>5.0%*
Severity: MILD
Onset: EARLY
Muscle Pain Incidence:
5.0-9.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
6.0-12.0%*
Severity: MILD
Onset: EARLY
No Menstrual Periods Incidence:
>10.0%*
Severity: MILD
Onset: DELAYED
Back Pain Incidence:
13.0-14.0%*
Severity: MILD
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Premarin 25mg Powder for Injection

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Minor Lifestyle Interaction
Grapefruit juice and Premarin 25mg Powder for Injection(Conjugated Estrogens)
Grapefruit juice and Estrogens(Conjugated Estrogens)
Grapefruit juice and grapefruit-containing foods may increase the side effects of estrogen in some females, such as nausea, breast tenderness, headache or fluid retention. There may be no interaction. Do not significantly change your grapefruit intake while taking estrogens for hormone replacement therapy or as part of hormonal birth control products. Report any unusual side effects, like unusual non-menstrual vaginal bleeding, promptly for evaluation.
Pregnancy & Lactation Information
Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


Learning More About
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