Premarin Vaginal Cream 0.625Mg Drug Medication Dosage Information
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Premarin: Vaginal cream (0.625mg)

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Premarin 0.625mg Vaginal Cr

What is this Medicine?

CONJUGATED ESTROGENS (CON ju gate ed ESS troe jenz) are a mixture of female hormones. This cream can help relieve symptoms associated with menopause.like vaginal dryness and irritation.

CVS Pharmacy Patient Statistics for Premarin: Vaginal cream(0.625mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information

Premarin 0.625mg Vaginal Cream

NDC: 000460872
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Menopause, Dyspareunia, Hot Flashes, Atrophic Vaginitis

Storage Information
Store between 68 to 77 degrees F, excursions permitted 59 to 86 degrees F
Premarin 0.625mg Vaginal Cream

Reported Side Effects for Premarin 0.625mg Vaginal Cream

Emotional Lability Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Elevated Hepatic Enzymes Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Abnormal Cervical Cells Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Increase In Breast Size Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Fluid From Breast Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Drug-Induced Acne Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Vomiting Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Inflamed Pancreas Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Yellow Skin Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Increased Blood Sugar Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Weight Gain Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Vaginal Irritation Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Blood Clot In Eye Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Skin Rash Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Liver Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Paresthesias Incidence:
<6.0%*
Severity: MILD
Onset: DELAYED
Heavy Menstrual Period Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Increased Sexual Desire Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Decreased Sexual Desire Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Irritability Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Galactorrhea Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Fluid Retention Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Rash Of Red Skin Bumps Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Melasma Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Breast Pain Incidence:
<14.0%*
Severity: MILD
Onset: DELAYED
High Triglycerides Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
High Blood Pressure Incidence:
<5.0%*
Severity: MODERATE
Onset: EARLY
Hirsutism Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Erythema Multiforme Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Swelling Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Loose Stools Incidence:
<7.0%*
Severity: MILD
Onset: EARLY
Gallstones Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Cholecystitis Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Hair Loss Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Acne Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Liver Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Cholestasis Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Itching Incidence:
<5.0%*
Severity: MILD
Onset: RAPID
Blockage Of Bile Duct Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Stomach Pain Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Hives Incidence:
<5.0%*
Severity: MILD
Onset: RAPID
Endometrial Hyperplasia Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Lightheadedness Incidence:
1.0-7.0%*
Severity: MILD
Onset: EARLY
Menstrual Cramps Incidence:
1.0-8.0%*
Severity: MILD
Onset: DELAYED
Weakness Incidence:
1.4-8.0%*
Severity: MILD
Onset: DELAYED
Tired Incidence:
1.4-8.0%*
Severity: MILD
Onset: EARLY
Nervousness Incidence:
2.0-5.0%*
Severity: MILD
Onset: DELAYED
Breakthrough Bleeding Incidence:
2.0-14.0%*
Severity: MILD
Onset: DELAYED
Inability To Sleep Incidence:
2.9-7.0%*
Severity: MILD
Onset: EARLY
Vaginal Discharge Incidence:
3.0-7.0%*
Severity: MILD
Onset: DELAYED
Vaginal Discharge Incidence:
3.0-7.0%*
Severity: MILD
Onset: DELAYED
Peripheral Vasodilation Incidence:
3.0-5.0%*
Severity: MODERATE
Onset: RAPID
Muscle Cramps Incidence:
3.0-7.0%*
Severity: MILD
Onset: DELAYED
Joint Pain Incidence:
3.5-14.0%*
Severity: MILD
Onset: DELAYED
Vaginal Infection Incidence:
4.2-7.0%*
Severity: MODERATE
Onset: DELAYED
Depression Incidence:
5.0-7.0%*
Severity: MODERATE
Onset: DELAYED
Headache Incidence:
>5.0%*
Severity: MILD
Onset: EARLY
Muscle Pain Incidence:
5.0-9.0%*
Severity: MILD
Onset: EARLY
Yeast Infection Incidence:
5.0-6.0%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
6.0-12.0%*
Severity: MILD
Onset: EARLY
No Menstrual Periods Incidence:
>10.0%*
Severity: MILD
Onset: DELAYED
Back Pain Incidence:
13.0-14.0%*
Severity: MILD
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Premarin 0.625mg Vaginal Cream

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Minor Lifestyle Interaction
Grapefruit juice and Premarin 0.625mg Vaginal Cream(Conjugated Estrogens)
Grapefruit juice and Estrogens(Conjugated Estrogens)
Grapefruit juice and grapefruit-containing foods may increase the side effects of estrogen in some females, such as nausea, breast tenderness, headache or fluid retention. There may be no interaction. Do not significantly change your grapefruit intake while taking estrogens for hormone replacement therapy or as part of hormonal birth control products. Report any unusual side effects, like unusual non-menstrual vaginal bleeding, promptly for evaluation.
Pregnancy & Lactation Information
Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


Learning More About
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