Primaxin Powder For Suspension For Injection 500-500Mg Drug Medication Dosage Information
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Primaxin: Powder for suspension for injection (500-500mg)

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What is this Medicine?

IMIPENEM; CILASTATIN (i mi PEN em; sye la STAT in) is a carbapenem antibiotic. It is used to treat certain kinds of bacterial infections. It will not work for colds, flu, or other viral infections.

In-Depth Information

Primaxin IM 500mg Powder for Injection

NDC: 000063582
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Pneumonia, Peritonitis, Gynecologic Infections, Cellulitis, Intraabdominal Infections, Skin And Skin Structure Infections, Endomyometritis, Nosocomial Pneumonia, Diabetic Foot Ulcer, Appendicitis, Bronchitis, Community-acquired Pneumonia

Sometimes used for but not FDA approved for the following conditions:
Cystic Fibrosis

Storage Information
Store at 77 degrees F
Primaxin IM 500mg Powder for Injection

Reported Side Effects for Primaxin IM 500mg Powder for Injection

Inflamed Tongue Incidence:
<0.2%*
Severity: MODERATE
Onset: EARLY
Flushing Incidence:
<0.2%*
Severity: MILD
Onset: RAPID
Elevated Hepatic Enzymes Incidence:
<17.9%*
Severity: MODERATE
Onset: DELAYED
Dyskinesia Incidence:
<0.2%*
Severity: MODERATE
Onset: DELAYED
Metallic Taste Incidence:
<0.2%*
Severity: MILD
Onset: EARLY
Cyanosis Incidence:
<0.2%*
Severity: SEVERE
Onset: EARLY
Confusion Incidence:
<0.2%*
Severity: MODERATE
Onset: EARLY
Chest Pain Incidence:
<0.2%*
Severity: MODERATE
Onset: EARLY
Weakness Incidence:
<0.2%*
Severity: MILD
Onset: DELAYED
Inceased Urination Incidence:
<0.2%*
Severity: MILD
Onset: EARLY
Low White Blood Cell Counts Incidence:
<0.2%*
Severity: MODERATE
Onset: DELAYED
Yellow Skin Incidence:
<0.2%*
Severity: MODERATE
Onset: DELAYED
Liver Infection Incidence:
<0.2%*
Severity: MODERATE
Onset: DELAYED
Brain Dysfunction Incidence:
<0.2%*
Severity: MODERATE
Onset: DELAYED
Weakness Incidence:
<0.2%*
Severity: MILD
Onset: EARLY
Urine Discoloration Incidence:
<1.1%*
Severity: MILD
Onset: EARLY
Lyell'S Syndrome Incidence:
<0.2%*
Severity: SEVERE
Onset: DELAYED
Tooth Discoloration Incidence:
<0.2%*
Severity: MILD
Onset: DELAYED
Tongue Discoloration Incidence:
<0.2%*
Severity: MILD
Onset: DELAYED
Rapid Heart Rate Incidence:
<1.5%*
Severity: MODERATE
Onset: RAPID
Kidney Failure Incidence:
<0.2%*
Severity: SEVERE
Onset: DELAYED
Paresthesias Incidence:
<0.2%*
Severity: MILD
Onset: DELAYED
Pancytopenia Incidence:
<0.2%*
Severity: SEVERE
Onset: DELAYED
Rapid Heart Rate Incidence:
<0.2%*
Severity: MODERATE
Onset: EARLY
Rapid Muscle Twitches Incidence:
<0.2%*
Severity: MODERATE
Onset: DELAYED
Overbreathing Incidence:
<0.2%*
Severity: MILD
Onset: EARLY
Liver Failure Incidence:
<0.2%*
Severity: SEVERE
Onset: DELAYED
Deafness Incidence:
<0.2%*
Severity: SEVERE
Onset: DELAYED
Hallucinations Incidence:
<0.2%*
Severity: MODERATE
Onset: EARLY
Shortness Of Breath Incidence:
<0.2%*
Severity: MODERATE
Onset: EARLY
Erythema Multiforme Incidence:
<0.2%*
Severity: SEVERE
Onset: DELAYED
Inflamed Colon Incidence:
<0.2%*
Severity: MODERATE
Onset: DELAYED
Headache Incidence:
<0.2%*
Severity: MILD
Onset: EARLY
Hemolytic Anemia Incidence:
<0.2%*
Severity: SEVERE
Onset: DELAYED
High Bilirubin Level Incidence:
<3.0%*
Severity: MODERATE
Onset: DELAYED
Excessive Sweating Incidence:
<0.2%*
Severity: MILD
Onset: DELAYED
Extra Saliva Production Incidence:
<0.2%*
Severity: MILD
Onset: EARLY
Yeast Infection Incidence:
<1.5%*
Severity: MODERATE
Onset: DELAYED
Low White Blood Cells Incidence:
<3.3%*
Severity: MODERATE
Onset: DELAYED
Joint Pain Incidence:
<0.2%*
Severity: MILD
Onset: DELAYED
Decreased Urination Incidence:
<2.2%*
Severity: SEVERE
Onset: EARLY
Inability To Urinate Incidence:
<2.2%*
Severity: SEVERE
Onset: DELAYED
Stomach Pain Incidence:
<0.2%*
Severity: MILD
Onset: EARLY
Balance Problems Incidence:
<0.2%*
Severity: MILD
Onset: EARLY
Shaking Incidence:
<0.2%*
Severity: MILD
Onset: EARLY
Distressed Incidence:
<0.2%*
Severity: MILD
Onset: EARLY
Ringing In Ears Incidence:
<0.2%*
Severity: MILD
Onset: DELAYED
Angioedema Incidence:
<0.2%*
Severity: SEVERE
Onset: RAPID
Low Platelet Count Incidence:
<0.2%*
Severity: MODERATE
Onset: DELAYED
Stevens-Johnson Syndrome Incidence:
<0.2%*
Severity: SEVERE
Onset: DELAYED
Heartburn Incidence:
<0.2%*
Severity: MILD
Onset: EARLY
Pseudomembranous Colitis Incidence:
<0.2%*
Severity: MODERATE
Onset: DELAYED
Infection Incidence:
0.1%*
Severity: MILD
Onset: DELAYED
Injection Site Reaction Incidence:
0.2-3.1%*
Severity: MILD
Onset: RAPID
Hives Incidence:
0.2%*
Severity: MILD
Onset: RAPID
Drowsiness Incidence:
0.2%*
Severity: MILD
Onset: EARLY
Vomiting Incidence:
0.3-1.5%*
Severity: MILD
Onset: EARLY
Itching Incidence:
0.3%*
Severity: MILD
Onset: RAPID
Lightheadedness Incidence:
0.3%*
Severity: MILD
Onset: EARLY
Skin Rash Incidence:
0.4-2.2%*
Severity: MILD
Onset: EARLY
Low Blood Pressure Incidence:
0.4%*
Severity: MODERATE
Onset: RAPID
Convulsions Incidence:
0.4-5.9%*
Severity: SEVERE
Onset: DELAYED
Fever Incidence:
0.5%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
0.6-3.9%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
0.6-2.0%*
Severity: MILD
Onset: EARLY
Eosinophilia Incidence:
12.8%*
Severity: MODERATE
Onset: DELAYED
High Platelet Count Incidence:
13.4%*
Severity: MODERATE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Compatible - This drug is generally safe to take by nursing mothers.


Learning More About
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