Propranolol Hydrochloride, Hydrochlorothiazide Oral Tablet 40-25Mg Drug Medication Dosage Information
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Propranolol Hydrochloride, Hydrochlorothiazide: Oral tablet (40-25mg)

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Drug Image file DrugItem_6755.JPG
Propranolol/HCTZ 40mg-25mg Tab
Mylan Pharmaceuticals Inc.
Pill Identification: MYLAN 731 

What is this Medicine?

HYDROCHLOROTHIAZIDE; PROPRANOLOL (hye droe klor oh THYE a zide; proe PRAN oh lole) is a combination of a diuretic and a beta-blocker. It is used to treat high blood pressure.

CVS Pharmacy Patient Statistics for Propranolol Hydrochloride, Hydrochlorothiazide: Oral tablet(40-25mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
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Propranolol Hydrochloride/Hydrochlorothiazide 40mg-25mg Tablet

NDC: 003780731
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Hypertension

Storage Information
Protect from moisture
Store at controlled room temperature (between 68 and 77 degrees F)
Protect from freezing
Avoid excessive heat (above 104 degrees F)
Propranolol Hydrochloride/Hydrochlorothiazide 40mg-25mg Tablet
Drug Image file DrugItem_6755.JPG
Mylan Pharmaceuticals Inc.
Pill Identification: MYLAN 731 
Shape: round
Color: white

Reported Side Effects for Propranolol Hydrochloride/Hydrochlorothiazide 40mg-25mg Tablet

Lupus-like Symptoms Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Hair Loss Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Dry Eyes Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Propranolol Hydrochloride/Hydrochlorothiazide 40mg-25mg Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Tobacco and Propranolol Hydrochloride/Hydrochlorothiazide 40mg-25mg Tablet(Propranolol Hydrochloride)
Tobacco and Propranolol Hydrochloride(Propranolol Hydrochloride)
Tobacco smoking may reduce the effectiveness of Propranolol for treating conditions like high blood pressure or chest pain. Tobacco smoke contains substances that speed the removal of Propranolol from the body, which can make this drug less effective. Also, Tobacco smoking may increase the blood pressure or contribute to the risk of heart disease and related problems. Alternatively, if you take Propranolol and suddenly stop Tobacco smoking, you may feel dizzy or faint, or slow heart rate or low blood pressure may occur. Make sure your prescriber is aware that you smoke Tobacco or if you plan to stop smoking.
Major Lifestyle Interaction
Marijuana and Propranolol Hydrochloride/Hydrochlorothiazide 40mg-25mg Tablet(Propranolol Hydrochloride)
Marijuana and Beta-blockers(Propranolol Hydrochloride)
Do not take Marijuana, Medical and Beta-Blockers (examples: Coreg, Metoprolol or Lopressor or Toprol, Nadolol or Corgard, Propranolol or Inderal) together without talking to your health care provider. Marijuana, Medical may decrease the effectiveness of Beta-Blockers. It is possible that Marijuana, Medical can cause high blood pressure, increased heart rate or other heart-related side effects in persons predisposed to these conditions, which may make the Beta-Blocker-type drug less effective at treating heart or blood pressure related problems.
Moderate Lifestyle Interaction
Alcohol and Propranolol Hydrochloride/Hydrochlorothiazide 40mg-25mg Tablet(Hydrochlorothiazide)
Alcohol and Antihypertensives(Hydrochlorothiazide)
Although an interaction is possible, Ethanol (alchohol) and Antihypertensive Agents (drugs used to reduce high blood pressure) may be used together. Ethanol or alchohol-containing beverages may increase the effects of Antihypertensive Agents on your blood pressure. If the blood pressure drops too low while taking Ethanol and Antihypertensive Agents, you may become dizzy or feel faint. To limit this interaction, avoid alcohol-containing beverages while taking medicines to lower your blood pressure. Do not stand or sit up too quickly. Contact your prescriber if you have dizziness which does not go away.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Compatible - This drug is generally safe to take by nursing mothers.


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