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Protonix: Oral tablet, gastro-resistant

Also see:
  • Reported side effects
  • Daily life interactions

Available Strengths
Drug Image file DrugItem_6709.JPG
Protonix 40mg DR Tablet
Wyeth Pharmaceuticals Inc, A subsidiary of Pfizer Inc
Pill Identification: PROTONIX 
Drug Image file DrugItem_5124.JPG
Protonix 20mg DR Tab
Wyeth Pharmaceuticals Inc, A subsidiary of Pfizer Inc
Pill Identification: P 20 
Drug Image file DrugItem_12259.JPG
Protonix 40mg DR Tab
PD-RX
Pill Identification: PROTONIX 
Drug Image file DrugItem_12258.JPG
Protonix 20mg DR Tab
PD-RX
Pill Identification: P 20 
How This Drug Works
Proton Pump Inhibitors (PPIs)
PPIs prevent the stomach from making acid. Stomach cells contain a protein called the proton pump. Food entering the stomach tells the protein to "pump". PPIs work by blocking the proton pump in stomach cells from moving to the cells surface.
Stomach cells contain hydrogen/potassium ATPase, a protein also called the proton pump.  Food entering the stomach, tells hydrogen/potassium ATPase to move from inside the cell to its surface and &#34;pump&#34; acidic hydrogen ions into the stomach in exchange for non&#45;acidic potassium ions. As more hydrogen builds up in the stomach, it becomes more acidic. Although some acid is required for digestion and to kill bacteria, high levels may cause indigestion and ulcers.<br><br>PPIs work by blocking the proton pump in stomach cells from moving to the cells surface. This prevents the pump from adding hydrogen to the stomach, which decreases the amount of acid in the stomach.
Watch a Video Showing How This Drug Works

Frequently Asked Questions (FAQs) on Protonix: Oral tablet, gastro-resistant

What is this medicine?

PANTOPRAZOLE (pan TOE pra zole) prevents the production of acid in the stomach. It is used to treat gastroesophageal reflux disease (GERD), inflammation of the esophagus, and Zollinger-Ellison syndrome.

What should I tell my health care provider before I take this medicine?

How should I use this medicine?

What if I miss a dose?

What may interact with this medicine?

What should I watch for while using this medicine?

What side effects may I notice from receiving this medicine?

Where should I keep my medicine?

Drugs Related by Class to Protonix: Oral tablet, gastro-resistant
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CVS Pharmacy Patient Statistics for Protonix: Oral tablet, gastro-resistant
Usage by Gender
62.51%
37.49%
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage by Age
0.24%
3.23%
26.28%
70.24%
In-Depth Information on This Drug
Select a specific strength to visit the detail page where you'll find :
  • Reported side effects
  • Daily life interactions
Select a Strength
Patient Experiences with Protonix

We want to help you stay educated about the medications you are taking. View other
patient's observations and share your own.

Be sure to consult your health care provider before taking any medications. Other
patient's comments should not be considered medical advice or health care provider
recommendations.

View All 3 Experiences
Average Scores
Easy to Take: 5.0 / 5
Works as Intended: 5.0 / 5
Tolerable: 5.0 / 5

Great for heartburn
Protonix has been very effective in controlling heartburn. I have taken it for 10 years, at least. Insurance has stopped covering it. Bums !
Helpful: 1
Unhelpful: 0
CVS Customer
April 11, 2015
From: Coatesville, PA
Age: 55-64
Gender: Male
Drug Form: Granules for oral suspension
Easy to Take: Strongly Agree
Works as Intended: Strongly Agree
Tolerable: Strongly Agree


Works as intended bad side effect
I was recently diagnosed with GERD. After having side effects from Prilosec, my doctor prescribed me this. After about a month I started to get horrible headaches daily and dry mouth. After stopping and switching to yet another similar medicine the headaches and dry mouth are gone!
Helpful: 1
Unhelpful: 0
CVS Customer
March 14, 2015
From: De Pere, WI
Age: 25-34
Gender: Female
Drug Form: Oral tablet, gastro-resistant
Easy to Take: Strongly Agree
Works as Intended: Agree
Tolerable: Strongly Disagree


Best drug available for GERD
I have had GERD for more than 20 years and have tried over a dozen different medications for relief. Protonix 40 mg has been the most effective with the least amount of side effects. Too bad it's so expensive that most health insurers have removed Protonix from their formulary.
Helpful: 6
Unhelpful: 2
CVS Customer
November 12, 2014
From: pittsburgh, PA
Age: 55-64
Gender: Male
Drug Form: Oral tablet, gastro-resistant
Easy to Take: Strongly Agree
Works as Intended: Strongly Agree
Tolerable: Strongly Agree