Protriptyline Oral Tablet 10Mg Drug Medication Dosage Information
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Protriptyline: Oral tablet (10mg)

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Drug Image file DrugItem_17338.JPG
Protriptyline 10mg Tab
Rising Pharmaceuticals Inc
Pill Identification: LOGO  |  7
Drug Image file DrugItem_11231.JPG
Protriptyline 10mg Tab
Roxane Laboratories Inc
Pill Identification: 54 694 

What is this Medicine?

PROTRIPTYLINE (proe TRIP ti leen) is used to treat depression.

CVS Pharmacy Patient Statistics for Protriptyline: Oral tablet(10mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
Select a Medication

Protriptyline Hydrochloride 10mg Tablet

NDC: 649800159
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Depression

Sometimes used for but not FDA approved for the following conditions:
Sleep Apnea

Storage Information
Store at controlled room temperature (between 68 and 77 degrees F)
Protriptyline Hydrochloride 10mg Tablet
Drug Image file DrugItem_17338.JPG
Rising Pharmaceuticals Inc
Pill Identification: LOGO  |  7
Shape: round
Color: yellow

Reported Side Effects for Protriptyline Hydrochloride 10mg Tablet

Liver Failure Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Eosinophilia Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Dystonic Reaction Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Dyskinesia Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Convulsions Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Serotonin Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Bruises Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Pseudoparkinsonism Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Underactive Thyroid Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Overactive Thyroid Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Enlarged Thyroid Gland Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Loose Stools Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Low White Blood Cell Counts Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Yellow Skin Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Liver Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
No White Blood Cells Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Low Platelet Count Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Lightheadedness Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Stomach Pain Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Yawning Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Blurred Vision Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: EARLY
Dysarthria Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Retaining Urine Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: EARLY
Tired Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Vomiting Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Weight Loss Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Drowsiness Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Decreased Appetite Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Elevated Hepatic Enzymes Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
>10.0%*
Severity: MILD
Onset: EARLY
Withdrawal Incidence:
>10.0%*
Severity: MODERATE
Onset: EARLY
Constipation Incidence:
>10.0%*
Severity: MODERATE
Onset: DELAYED
Ejaculation Dysfunction Incidence:
>10.0%*
Severity: MODERATE
Onset: DELAYED
Shaking Incidence:
>10.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
>10.0%*
Severity: MILD
Onset: EARLY
Headache Incidence:
>10.0%*
Severity: MILD
Onset: EARLY
Inability To Sleep Incidence:
>10.0%*
Severity: MILD
Onset: EARLY
Dry Mouth Incidence:
>10.0%*
Severity: MILD
Onset: EARLY
Impotence (erectile Dysfunction) Incidence:
>10.0%*
Severity: MODERATE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Protriptyline Hydrochloride 10mg Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Alcohol and Protriptyline Hydrochloride 10mg Tablet(Protriptyline Hydrochloride)
Alcohol and CNS Depressants(Protriptyline Hydrochloride)
Avoid alcohol-containing drinks while taking this medicine. Using this drug along with alcohol can lead to serious side effects. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery until you know how this drug affects you, and especially if you are drinking alcohol-containing beverages. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.
Major Lifestyle Interaction
Marijuana and Protriptyline Hydrochloride 10mg Tablet(Protriptyline Hydrochloride)
Marijuana and Tricyclic antidepressants(Protriptyline Hydrochloride)
Do not take Marijuana, Medical and Tricyclic Antidepressants together without talking to your health care provider. Taking these drugs together might increase the risk of high blood pressure or heart rate, nervousness, palpitations, problems with sleep, severe headache, or other side effects.
Moderate Lifestyle Interaction
Tobacco and Protriptyline Hydrochloride 10mg Tablet(Protriptyline Hydrochloride)
Tobacco and Tricyclic antidepressants(Protriptyline Hydrochloride)
Tobacco smoking may reduce the effectiveness of this drug in treating your condition. Tobacco smoke contains substances that speed the removal of this drug from the body, which in theory can make this drug less effective. Alternatively, if you take this drug and suddenly stop Tobacco smoking, you may experience drug-related side effects like confusion, constipation, dizziness, difficulty with urination, dry mouth and eyes or drowsiness. Make sure your prescriber is aware that you smoke Tobacco or if you plan to stop smoking.
Pregnancy & Lactation Information
Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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