Pylera Oral Capsule 140-125-125Mg Drug Medication Dosage Information
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Pylera: Oral capsule (140-125-125mg)

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Pylera Cap

What is this Medicine?

BISMUTH SUBCITRATE POTASSIUM; METRONIDAZOLE; TETRACYCLINE (BIZ muth sub SIH trayt poe TAS ee um; me troe NI da zole; tet ra SYE kleen) is an antibiotic. It is used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection.

CVS Pharmacy Patient Statistics for Pylera: Oral capsule(140-125-125mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
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Pylera 140mg-125mg-125mg Capsule

NDC: 589140600
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Helicobacter Pylori (H. Pylori) Eradication, Duodenal Ulcer

Sometimes used for but not FDA approved for the following conditions:
Dyspepsia, Gastric Ulcer

Storage Information
Store at controlled room temperature (between 68 and 77 degrees F)
Pylera 140mg-125mg-125mg Capsule

Reported Side Effects for Pylera 140mg-125mg-125mg Capsule

Belching Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Chest Pain Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Back Pain Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Causing To Be Hungry Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Vomiting Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Weight Gain Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Tongue Discoloration Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Rapid Heart Rate Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Painful Swallowing Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Feeling Sick Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Liver Failure Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Throat Ulcers Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Muscle Pain Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Inflamed Stomach Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Gas Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Tired Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Exfoliative Dermatitis Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Throat Inflammation Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Drowsiness Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Nervousness Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Inflamed Pancreas Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Liver Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Difficulty Swallowing Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Skin Rash Incidence:
0.7%*
Severity: MILD
Onset: EARLY
Rash With Pustules Incidence:
1.4%*
Severity: MILD
Onset: EARLY
Dry Mouth Incidence:
1.4%*
Severity: MILD
Onset: EARLY
Elevated Hepatic Enzymes Incidence:
1.4%*
Severity: MODERATE
Onset: DELAYED
Constipation Incidence:
1.4%*
Severity: MODERATE
Onset: DELAYED
Vaginal Infection Incidence:
2.7%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
2.7%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
2.7%*
Severity: MILD
Onset: EARLY
Weakness Incidence:
3.4%*
Severity: MILD
Onset: DELAYED
Metallic Taste Incidence:
4.1%*
Severity: MILD
Onset: EARLY
Stomach Pain Incidence:
4.8%*
Severity: MILD
Onset: EARLY
Headache Incidence:
5.4%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
6.8%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
8.2%*
Severity: MILD
Onset: EARLY
Stool Discoloration Incidence:
15.6%*
Severity: MILD
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Pylera 140mg-125mg-125mg Capsule

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Severe Lifestyle Interaction
Alcohol and Pylera 140mg-125mg-125mg Capsule(Metronidazole)
Alcohol and Metronidazole(Metronidazole)
When Alcohol is taken by patients receiving Metronidazole, an extremely unpleasant reaction can occur. This reaction includes flushing, throbbing headache, nausea, vomiting, sweating, thirst, and other effects that may last from 30 minutes to several hours. You should not drink alcoholic beverages or use medicines that contain a large amount of alcohol while taking Metronidazole. Also continue to avoid Alcohol for about 2-3 days after stopping Metronidazole. Interactions with Metronidazole vaginal or topical skin products are not likely.
Major Lifestyle Interaction
Food and Pylera 140mg-125mg-125mg Capsule(Metronidazole)
Food and Metronidazole(Metronidazole)
Most forms of metronidazole may be taken without regard to meals or food. However, extended-release metronidazole tablets, like Flagyl ER, should be taken on an empty stomach 1 hour before or 2 hours after meals. Do not use alcoholic beverages (or take alcohol-containing medicines) while taking or within 2-3 days after stopping Metronidazole to limit the possibility of side effects. When Alcohol is taken by patients receiving Metronidazole, an extremely unpleasant reaction can occur. This reaction includes flushing, throbbing headache, nausea, vomiting, sweating, thirst, and other effects that may last from 30 minutes to several hours. Interactions with Metronidazole vaginal or topical skin products are not likely.
Major Lifestyle Interaction
Calcium-containing foods and Pylera 140mg-125mg-125mg Capsule(Tetracycline Hydrochloride)
Calcium-containing foods and Tetracycline Hydrochloride(Tetracycline Hydrochloride)
Specific food that is high in calcium such as dairy products (cheese, milk, yogurt, or cottage cheese) can decrease the absorption of Tetracycline (Antibiotic) from the stomach. Taking dairy product or other high-calcium foods together together with Tetracycline can decrease the effectiveness of Tetracycline to treat an infection. To limit this interaction, take Tetracycline at least 1 hour before or 2 hours after meals or milk.
Major Lifestyle Interaction
Foods High in Iron and Pylera 140mg-125mg-125mg Capsule(Tetracycline Hydrochloride)
Foods High in Iron and Tetracycline Hydrochloride(Tetracycline Hydrochloride)
Specific food that is high in calcium such as dairy products (cheese, milk, yogurt, or cottage cheese) can decrease the absorption of Tetracycline (Antibiotic) from the stomach. Taking dairy product or other high-calcium foods together together with Tetracycline can decrease the effectiveness of Tetracycline to treat an infection. To limit this interaction, take Tetracycline at least 1 hour before or 2 hours after meals or milk.
Pregnancy & Lactation Information
FIRST Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

SECOND Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

THIRD Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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