Ranexa Oral Tablet, Extended Release 1000Mg Drug Medication Dosage Information
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Ranexa: Oral tablet, extended release (1000mg)

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Drug Image file DrugItem_16503.JPG
Ranexa 1000mg ER Tab
Gilead Sciences Inc
Pill Identification: GSI1000 
Drug Image file default-drug-image.png
Ranexa 1000mg ER Tab

What is this Medicine?

RANOLAZINE (ra NOE la zeen) is a heart medicine. It is used to treat chronic chest pain (angina). This medicine must be taken regularly. It will not relieve an acute episode of chest pain.

CVS Pharmacy Patient Statistics for Ranexa: Oral tablet, extended release(1000mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
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Ranexa 1000mg Extended-Release Tablet

NDC: 619581004
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Angina

Sometimes used for but not FDA approved for the following conditions:
Unstable Angina, Acute Myocardial Infarction, NSTEMI

Storage Information
Store at 77 degrees F; excursions permitted to 59-86 degrees F
Ranexa 1000mg Extended-Release Tablet
Drug Image file DrugItem_16503.JPG
Gilead Sciences Inc
Pill Identification: GSI1000 
Shape: oblong
Color: yellow

Reported Side Effects for Ranexa 1000mg Extended-Release Tablet

Low White Blood Cell Counts Incidence:
<0.5%*
Severity: MODERATE
Onset: DELAYED
Low Kidney Function Incidence:
<0.5%*
Severity: SEVERE
Onset: DELAYED
Shaking Incidence:
<0.5%*
Severity: MILD
Onset: EARLY
Low Platelet Count Incidence:
<0.5%*
Severity: MODERATE
Onset: DELAYED
Pulmonary Fibrosis Incidence:
<0.5%*
Severity: SEVERE
Onset: DELAYED
Eosinophilia Incidence:
<0.5%*
Severity: MODERATE
Onset: DELAYED
Hypoesthesia Incidence:
<0.5%*
Severity: MILD
Onset: DELAYED
Pancytopenia Incidence:
<0.5%*
Severity: SEVERE
Onset: DELAYED
Paresthesias Incidence:
<0.5%*
Severity: MILD
Onset: DELAYED
Kidney Failure Incidence:
<0.5%*
Severity: SEVERE
Onset: DELAYED
Angioedema Incidence:
<0.5%*
Severity: SEVERE
Onset: RAPID
Confusion Incidence:
0.5-4.0%*
Severity: MODERATE
Onset: EARLY
Rapid Heart Rate Incidence:
0.5-4.0%*
Severity: MODERATE
Onset: EARLY
Blurred Vision Incidence:
0.5-4.0%*
Severity: MODERATE
Onset: EARLY
Weakness Incidence:
0.5-4.0%*
Severity: MILD
Onset: DELAYED
Vomiting Incidence:
0.5-4.0%*
Severity: MILD
Onset: EARLY
Fainting Incidence:
0.5-4.0%*
Severity: MILD
Onset: EARLY
Decreased Appetite Incidence:
0.5-4.0%*
Severity: MILD
Onset: DELAYED
Slow Heart Beat Incidence:
0.5-4.0%*
Severity: SEVERE
Onset: RAPID
Upset Stomach Incidence:
0.5-4.0%*
Severity: MILD
Onset: EARLY
Shortness Of Breath Incidence:
0.5-4.0%*
Severity: MODERATE
Onset: EARLY
Excessive Sweating Incidence:
0.5-4.0%*
Severity: MILD
Onset: DELAYED
Low Blood Pressure Incidence:
0.5-4.0%*
Severity: MODERATE
Onset: RAPID
Postural Low Blood Pressure Incidence:
0.5-4.0%*
Severity: MODERATE
Onset: DELAYED
Ringing In Ears Incidence:
0.5-4.0%*
Severity: MILD
Onset: DELAYED
Balance Problems Incidence:
0.5-4.0%*
Severity: MILD
Onset: EARLY
Dry Mouth Incidence:
0.5-4.0%*
Severity: MILD
Onset: EARLY
Stomach Pain Incidence:
0.5-4.0%*
Severity: MILD
Onset: EARLY
Blood In The Urine Incidence:
0.5-4.0%*
Severity: MODERATE
Onset: DELAYED
Fluid Retention Incidence:
0.5-4.0%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
4.4%*
Severity: MILD
Onset: EARLY
Constipation Incidence:
4.5%*
Severity: MODERATE
Onset: DELAYED
Headache Incidence:
5.5%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
6.2%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Ranexa 1000mg Extended-Release Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Grapefruit juice and Ranexa 1000mg Extended-Release Tablet(Ranolazine)
Grapefruit juice and Ranolazine(Ranolazine)
Avoid taking Ranolazine with grapefruit juice. Grapefruit juice and grapefruit-containing foods may increase the risk of serious side effects from Ranolazine. A change in the dose of Ranolazine may be necessary if Ranolazine and grapefuit juice are used together. Contact your prescriber immediately if you experience chest pain, dizziness, fainting or falling spells, palpitations, or changes in your usual heart rate (fast, slow, or irregular heart beats) while taking Ranolazine.
Moderate Lifestyle Interaction
Marijuana and Ranexa 1000mg Extended-Release Tablet(Ranolazine)
Marijuana and Ranolazine(Ranolazine)
Ranolazine can theoretically decrease the elimination of Marijuana, Medical from the body. Side effects from Marijuana, Medical may worsen if you take Ranolazine. You may feel drowsy or more tired. Do not drive or operate machinery until you know how these drugs affect you. Contact your health care provider immediately if you notice slurred speech, confusion, increases heart rate, or palpitations while taking Marijuana, Medical.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


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