Rheumatrex Oral Tablet 2.5Mg Drug Medication Dosage Information
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Rheumatrex: Oral tablet (2.5mg)

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Rheumatrex 2.5mg Dose Pack Tab
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Rheumatrex 2.5mg Dose Pack Tab
Drug Image file default-drug-image.png
Rheumatrex 2.5mg Dose Pack Tab
Drug Image file default-drug-image.png
Rheumatrex 2.5mg Dose Pack Tab
Drug Image file default-drug-image.png
Rheumatrex 2.5mg Dose Pack Tab

What is this Medicine?

METHOTREXATE (METH oh TREX ate) is a chemotherapy drug used to treat cancer including breast cancer, leukemia, and lymphoma. This medicine can also be used to treat psoriasis and certain kinds of arthritis.

CVS Pharmacy Patient Statistics for Rheumatrex: Oral tablet(2.5mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
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Rheumatrex 2.5mg Dose Pack Tablet

NDC: 672530580
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Mycosis Fungoides, Non-Hodgkin's Lymphoma (NHL), Small Cell Lung Cancer (SCLC), Choriocarcinoma, Acute Lymphocytic Leukemia (ALL), Cutaneous T-cell Lymphoma (CTCL), Leukemic Meningitis, Trophoblastic Disease, Lung Cancer, Burkitt's Lymphoma, Psoriasis, Hydatidiform Mole, Polyarticular Juvenile Idiopathic Arthritis, Head And Neck Cancer

Sometimes used for but not FDA approved for the following conditions:
Pruritus, Systemic Lupus Erythematosus (SLE), Dermatomyositis, Biliary Cirrhosis, Psoriatic Arthritis, Sarcoidosis, Rheumatoid Arthritis, Polymyositis, Bladder Cancer

Rheumatrex 2.5mg Dose Pack Tablet

Reported Side Effects for Rheumatrex 2.5mg Dose Pack Tablet

Chest Pain Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Vaginal Discharge Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Eye Irritation Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Excessive Sweating Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Headache Incidence:
<1.2%*
Severity: MILD
Onset: EARLY
Fever Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Nose Bleed Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Painful Urination Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Cough Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Infection Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Ringing In Ears Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Anemia Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Decreased Appetite Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Joint Pain Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Liver Disease Incidence:
0.1%*
Severity: SEVERE
Onset: DELAYED
Lightheadedness Incidence:
0.2-3.0%*
Severity: MILD
Onset: EARLY
Skin Rash Incidence:
0.2-3.0%*
Severity: MILD
Onset: EARLY
Hair Loss Incidence:
0.5-10.0%*
Severity: MILD
Onset: DELAYED
Loose Stools Incidence:
1.0-11.0%*
Severity: MILD
Onset: EARLY
Pancytopenia Incidence:
1.0-3.0%*
Severity: SEVERE
Onset: DELAYED
Lung Inflammation Incidence:
1.0%*
Severity: MODERATE
Onset: DELAYED
Itching Incidence:
1.0-3.0%*
Severity: MILD
Onset: RAPID
Low White Blood Cell Counts Incidence:
1.0-3.0%*
Severity: MODERATE
Onset: DELAYED
Mouth Ulcers Incidence:
2.0-11.0%*
Severity: MODERATE
Onset: DELAYED
Photosensitivity Incidence:
3.0-10.0%*
Severity: MILD
Onset: DELAYED
Low Platelet Count Incidence:
3.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Vomiting Incidence:
10.0-11.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
10.0-11.0%*
Severity: MILD
Onset: EARLY
Elevated Hepatic Enzymes Incidence:
14.0-15.0%*
Severity: MODERATE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Rheumatrex 2.5mg Dose Pack Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Alcohol and Rheumatrex 2.5mg Dose Pack Tablet(Methotrexate Sodium)
Alcohol and Methotrexate(Methotrexate Sodium)
Ingesting alcoholic beverages during methotrexate therapy may increase the risk for liver-related problems. You should avoid alcoholic drinks during methotrexate therapy.
Moderate Lifestyle Interaction
Food and Rheumatrex 2.5mg Dose Pack Tablet(Methotrexate Sodium)
Food and Methotrexate(Methotrexate Sodium)
Certain food or drink such as cola may increase the risk of methotrexate side effects. Tell your doctor if you drink soft drinks before you take methotrexate. Immediately report any ununsual symptom such as stomach pain, sore throat, fever, mouth sores, or problems with urination.
Moderate Lifestyle Interaction
Foods that acidify the urine and Rheumatrex 2.5mg Dose Pack Tablet(Methotrexate Sodium)
Foods that acidify the urine and Methotrexate(Methotrexate Sodium)
Certain food or drink such as cola may increase the risk of methotrexate side effects. Tell your doctor if you drink soft drinks before you take methotrexate. Immediately report any ununsual symptom such as stomach pain, sore throat, fever, mouth sores, or problems with urination.
Pregnancy & Lactation Information
FIRST Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

SECOND Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

THIRD Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


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