Simbrinza Ophthalmic Drops, Suspension 1-0.2pct Drug Medication Dosage Information
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SIMBRINZA: Ophthalmic drops, suspension (1-0.2%)

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What is this Medicine?

BRIMONIDINE; BRINZOLAMIDE (bri MOE ni deen; bryn XOE la mide) is used to treat open-angle glaucoma and high pressure in the eye.

In-Depth Information

SIMBRINZA 1%-0.2% Ophthalmic Suspension

NDC: 000654147
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Glaucoma, Ocular Hypertension

Storage Information
Store between 36 to 77 degrees F
SIMBRINZA 1%-0.2% Ophthalmic Suspension

Reported Side Effects for SIMBRINZA 1%-0.2% Ophthalmic Suspension

Itchy Eyes Incidence:
<30.0%*
Severity: MILD
Onset: RAPID
Sore Throat Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Hives Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Dry Mouth Incidence:
<30.0%*
Severity: MILD
Onset: EARLY
Fainting Incidence:
<3.0%*
Severity: MILD
Onset: EARLY
Abnormal Heart Rhythm Incidence:
<3.0%*
Severity: SEVERE
Onset: EARLY
Chest Pain Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Conjunctivitis Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Double Vision Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
<9.0%*
Severity: MILD
Onset: EARLY
Foreign Body Sensation Incidence:
<30.0%*
Severity: MILD
Onset: RAPID
Excessive Mucle Tone Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Keratopathy Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Dry Nose Incidence:
<3.0%*
Severity: MILD
Onset: EARLY
Bleeding Within The Eye Incidence:
<3.0%*
Severity: SEVERE
Onset: DELAYED
Rapid Heart Rate Incidence:
<3.0%*
Severity: MODERATE
Onset: EARLY
Upset Stomach Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Drowsiness Incidence:
<30.0%*
Severity: MILD
Onset: EARLY
Depression Incidence:
<3.0%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Shortness Of Breath Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Red Eyes Incidence:
<30.0%*
Severity: MODERATE
Onset: EARLY
Tired Incidence:
<30.0%*
Severity: MILD
Onset: EARLY
Headache Incidence:
<30.0%*
Severity: MILD
Onset: EARLY
High Blood Pressure Incidence:
<3.0%*
Severity: MODERATE
Onset: EARLY
Inability To Sleep Incidence:
<3.0%*
Severity: MILD
Onset: EARLY
Nervousness Incidence:
<3.0%*
Severity: MILD
Onset: DELAYED
Eye Inflammatoin Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Inflamed Eye Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Hair Loss Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Inflamed Eyes Incidence:
1.0-9.0%*
Severity: MODERATE
Onset: EARLY
Rhinitis Incidence:
1.0-5.0%*
Severity: MILD
Onset: EARLY
Allergic Skin Reaction Incidence:
1.0-5.0%*
Severity: MODERATE
Onset: DELAYED
Eye Drainage Incidence:
1.0-5.0%*
Severity: MILD
Onset: DELAYED
Eye Pain Incidence:
1.0-9.0%*
Severity: MILD
Onset: EARLY
Skin Redness Incidence:
3.0-9.0%*
Severity: MODERATE
Onset: EARLY
Metallic Taste Incidence:
3.0-5.0%*
Severity: MILD
Onset: EARLY
Muscle And/Or Bone Pain Incidence:
3.0-9.0%*
Severity: MILD
Onset: EARLY
Swelling Incidence:
3.0-9.0%*
Severity: MODERATE
Onset: DELAYED
Blurred Vision Incidence:
3.0-5.0%*
Severity: MODERATE
Onset: EARLY
Eye Irritation Incidence:
3.0-5.0%*
Severity: MILD
Onset: RAPID
Swollen Eyelids Incidence:
3.0-9.0%*
Severity: MILD
Onset: EARLY
Weakness Incidence:
3.0-9.0%*
Severity: MILD
Onset: DELAYED
Dry Eyes Incidence:
3.0-5.0%*
Severity: MILD
Onset: EARLY
Visual Impairment Incidence:
3.0-9.0%*
Severity: SEVERE
Onset: EARLY
Light Sensitivity Incidence:
3.0-9.0%*
Severity: MODERATE
Onset: EARLY
Corneal Erosion Incidence:
3.0-9.0%*
Severity: SEVERE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for SIMBRINZA 1%-0.2% Ophthalmic Suspension

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Moderate Lifestyle Interaction
Alcohol and SIMBRINZA 1%-0.2% Ophthalmic Suspension(Brimonidine Tartrate)
Alcohol and Brimonidine Tartrate(Brimonidine Tartrate)
Avoid or minimize your intake of Ethanol (alcohol-containing drinks) while taking Brimonidine Eye Solution. You may feel drowsy or more tired; do not drive or operate machinery while taking these products together.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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Patient Experiences with SIMBRINZA

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