Sinemet Oral Tablet 10-100Mg Drug Medication Dosage Information
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SINEMET: Oral tablet (10-100mg)

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SINEMET 10mg-100mg Tab

What is this Medicine?

CARBIDOPA;LEVODOPA (kar bi DOE pa; lee voe DOE pa) is used to treat the symptoms of Parkinson's disease.

CVS Pharmacy Patient Statistics for SINEMET: Oral tablet(10-100mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
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SINEMET 10mg-100mg Tablet

NDC: 000063915
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Parkinson's Disease, Parkinsonism

Sometimes used for but not FDA approved for the following conditions:
Restless Legs Syndrome (RLS), Amblyopia

Storage Information
Protect from light
Protect from moisture
Store at 77 degrees F; excursions permitted to 59-86 degrees F
SINEMET 10mg-100mg Tablet

Reported Side Effects for SINEMET 10mg-100mg Tablet

Nerve Pain Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Skin Rash Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Postural Low Blood Pressure Incidence:
<73.0%*
Severity: MODERATE
Onset: DELAYED
Nervousness Incidence:
<8.0%*
Severity: MILD
Onset: DELAYED
Constipation Incidence:
0.2-22.0%*
Severity: MODERATE
Onset: DELAYED
Shortness Of Breath Incidence:
0.4-1.6%*
Severity: MODERATE
Onset: EARLY
Loose Stools Incidence:
0.6-5.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
0.6-5.0%*
Severity: MILD
Onset: EARLY
Back Pain Incidence:
0.6-1.6%*
Severity: MILD
Onset: DELAYED
Dystonic Reaction Incidence:
0.8-1.8%*
Severity: MODERATE
Onset: DELAYED
Chest Pain Incidence:
0.8-1.0%*
Severity: MODERATE
Onset: EARLY
Muscle Cramps Incidence:
0.8-1.0%*
Severity: MILD
Onset: DELAYED
Paresthesias Incidence:
0.8-1.1%*
Severity: MILD
Onset: DELAYED
Headache Incidence:
1.0-17.0%*
Severity: MILD
Onset: EARLY
Inability To Sleep Incidence:
1.0-6.0%*
Severity: MILD
Onset: EARLY
Psychosis Incidence:
1.0-5.0%*
Severity: MODERATE
Onset: EARLY
Infection Incidence:
1.0-8.0%*
Severity: MILD
Onset: DELAYED
Decreased Appetite Incidence:
1.1-1.2%*
Severity: MILD
Onset: DELAYED
Dry Mouth Incidence:
1.1-7.0%*
Severity: MILD
Onset: EARLY
Depression Incidence:
1.3-11.0%*
Severity: MODERATE
Onset: DELAYED
Vomiting Incidence:
1.8-5.0%*
Severity: MILD
Onset: EARLY
Dyskinesia Incidence:
2.0-16.5%*
Severity: MODERATE
Onset: DELAYED
Lightheadedness Incidence:
2.3-19.0%*
Severity: MILD
Onset: EARLY
Confusion Incidence:
2.3-8.0%*
Severity: MODERATE
Onset: EARLY
Hallucinations Incidence:
3.0-5.0%*
Severity: MODERATE
Onset: EARLY
Upset Stomach Incidence:
3.0-30.0%*
Severity: MILD
Onset: EARLY
Uncontrolled Movements Incidence:
>10.0%*
Severity: MODERATE
Onset: DELAYED
Urine Discoloration Incidence:
>10.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for SINEMET 10mg-100mg Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Foods with high protein content and SINEMET 10mg-100mg Tablet(Levodopa)
Foods with high protein content and Levodopa(Levodopa)
For the best effect, take Levodopa at least 30 minutes before or 1 hour after you take food or meals. Taking Levodopa with food can decrease the drug's absorption into the body. Especially do not take Levodopa with foods that have a high protein, fat or fiber content.
Major Lifestyle Interaction
High Fat Foods and SINEMET 10mg-100mg Tablet(Levodopa)
High Fat Foods and Levodopa(Levodopa)
For the best effect, take Levodopa at least 30 minutes before or 1 hour after you take food or meals. Taking Levodopa with food can decrease the drug's absorption into the body. Especially do not take Levodopa with foods that have a high protein, fat or fiber content.
Major Lifestyle Interaction
High Fiber Foods and SINEMET 10mg-100mg Tablet(Levodopa)
High Fiber Foods and Levodopa(Levodopa)
For the best effect, take Levodopa at least 30 minutes before or 1 hour after you take food or meals. Taking Levodopa with food can decrease the drug's absorption into the body. Especially do not take Levodopa with foods that have a high protein, fat or fiber content.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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