Sprycel Oral Tablet 100Mg Drug Medication Dosage Information
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Sprycel: Oral tablet (100mg)

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What is this Medicine?

DASATINIB (da SA ti nib) is a medicine that targets specific proteins in cancer cells and stops the cancer cells from growing. It is used to treat some kinds of leukemia.

In-Depth Information

Sprycel 100mg Tablet

NDC: 000030852
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Acute Lymphocytic Leukemia (ALL), Chronic Myelogenous Leukemia (CML)

Storage Information
Store between 68 to 77 degrees F, excursions permitted 59 to 86 degrees F
Sprycel 100mg Tablet

Reported Side Effects for Sprycel 100mg Tablet

Heart Failure Incidence:
<4.0%*
Severity: SEVERE
Onset: DELAYED
High Bilirubin Level Incidence:
<6.0%*
Severity: SEVERE
Onset: DELAYED
Rash With Pustules Incidence:
<2.0%*
Severity: SEVERE
Onset: EARLY
Low Calcium Levels Incidence:
<12.0%*
Severity: SEVERE
Onset: DELAYED
Low Potassium Levels Incidence:
<15.0%*
Severity: SEVERE
Onset: DELAYED
Livedo Reticularis Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Bowel Obstruction Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Inflamed Heart Muscle Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Inflamed Optic Nerve Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Fluid Around The Heart Incidence:
<4.0%*
Severity: SEVERE
Onset: DELAYED
Bruise Incidence:
<6.0%*
Severity: MODERATE
Onset: EARLY
Fluid Around The Lungs Incidence:
<4.0%*
Severity: SEVERE
Onset: DELAYED
Aborted Pregnancy Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Fluid In Lungs Incidence:
<4.0%*
Severity: SEVERE
Onset: EARLY
Blood Clot In Lung Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Skin Redness Incidence:
<2.0%*
Severity: SEVERE
Onset: EARLY
Elevated Hepatic Enzymes Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Bruise Incidence:
<6.0%*
Severity: MILD
Onset: DELAYED
Incoordination Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Type Of Anemia Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Inflamed Blood Vessels Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Vaginal Bleeding Incidence:
<6.0%*
Severity: MODERATE
Onset: DELAYED
Blood In The Urine Incidence:
<6.0%*
Severity: MODERATE
Onset: DELAYED
Brain Attack Incidence:
<0.1%*
Severity: SEVERE
Onset: EARLY
Infection Incidence:
<7.0%*
Severity: SEVERE
Onset: DELAYED
Bleeding In The Brain Incidence:
<3.0%*
Severity: SEVERE
Onset: DELAYED
Convulsions Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Inflamed Pancreas Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Long Qt Syndrome Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Upset Stomach Incidence:
<3.0%*
Severity: SEVERE
Onset: EARLY
Acute Lung Injury Incidence:
<0.1%*
Severity: SEVERE
Onset: EARLY
Abnormality In Rectum Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Vesicular Rash Incidence:
<2.0%*
Severity: SEVERE
Onset: DELAYED
Joint Pain Incidence:
<12.0%*
Severity: MILD
Onset: DELAYED
Blood Clot Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Suddenly Stopped Heart Incidence:
<0.1%*
Severity: SEVERE
Onset: EARLY
Skin Irritation Incidence:
<2.0%*
Severity: SEVERE
Onset: EARLY
Skin Rash Incidence:
<2.0%*
Severity: SEVERE
Onset: EARLY
Red Spotted Rash Incidence:
<6.0%*
Severity: MILD
Onset: DELAYED
Loose Stools Incidence:
<5.0%*
Severity: SEVERE
Onset: EARLY
Shortness Of Breath Incidence:
<3.0%*
Severity: SEVERE
Onset: EARLY
Headache Incidence:
<3.0%*
Severity: SEVERE
Onset: EARLY
Fever Incidence:
<3.0%*
Severity: SEVERE
Onset: EARLY
Tired Incidence:
<4.0%*
Severity: SEVERE
Onset: EARLY
Exfoliative Dermatitis Incidence:
<21.0%*
Severity: SEVERE
Onset: DELAYED
Muscle And/Or Bone Pain Incidence:
<22.0%*
Severity: MILD
Onset: EARLY
Erythema Multiforme Incidence:
<21.0%*
Severity: SEVERE
Onset: DELAYED
Nose Bleed Incidence:
<6.0%*
Severity: MILD
Onset: DELAYED
Swelling Incidence:
<22.0%*
Severity: MODERATE
Onset: DELAYED
Bleeding Within The Eye Incidence:
<6.0%*
Severity: SEVERE
Onset: DELAYED
Feeling Sick Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Breakdown Of Muscle Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Dead Bone Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Visual Impairment Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: EARLY
Hand And Foot Syndrome Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Fainting Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Low Lymphocytes Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Tumor Lysis Syndrome (TLS) Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Enlarged Lymph Nodes Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Skin Ulcer Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Stomach Ulcer Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Loss Of Memory Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Deafness Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Breathing Difficulties Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: RAPID
Blistery Rash Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Confusion Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Conjunctivitis Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Hoarseness Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Increased Urination Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Decreased Sexual Desire Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Kidney Failure Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Gynecomastia Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Rash Of Red Skin Bumps Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Photosensitivity Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Irritated Blood Vessels Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: RAPID
Secretion Of Tears Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Heartburn Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Shaking Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
High Pressure In Lungs Incidence:
0.1-5.0%*
Severity: SEVERE
Onset: DELAYED
Rapid Heart Rate Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: EARLY
Throat Inflammation Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Balance Problems Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Cholecystitis Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Protein In The Urine Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Extra Abdominal Fluid Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Nervousness Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Chest Pain Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Cholestasis Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Difficulty Swallowing Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Light Sensitivity Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Liver Infection Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Low Albumin In Blood Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Irregular Periods Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Inflamed Heart Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Low Blood Pressure Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: RAPID
High Blood Pressure Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: EARLY
Excessive Sweating Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Inflamed Stomach Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
High Uric Acid Level Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Inflamed Intestine Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Upset Stomach Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Rapid Heart Rate Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: EARLY
Drowsiness Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Depression Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Cough Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Constipation Incidence:
1.0%*
Severity: SEVERE
Onset: DELAYED
Inflamed Colon Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Rapid Heart Rate Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: RAPID
Scaly And Itchy Rashes Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Weakness Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Weight Gain Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Weight Loss Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Hair Loss Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Acne Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Nerve Pain Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Bleeding Incidence:
1.0-9.0%*
Severity: SEVERE
Onset: EARLY
Stomach Pain Incidence:
1.0%*
Severity: SEVERE
Onset: EARLY
Weakness Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Dry Skin Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Blurred Vision Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: EARLY
Dry Eyes Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Chest Pain Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: EARLY
Chills Incidence:
1.0-10.0%*
Severity: MILD
Onset: RAPID
Hives Incidence:
1.0-10.0%*
Severity: MILD
Onset: RAPID
Lightheadedness Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Inability To Sleep Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Lung Inflammation Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Flushing Incidence:
1.0-10.0%*
Severity: MILD
Onset: RAPID
Itching Incidence:
1.0%*
Severity: SEVERE
Onset: RAPID
Mouth Ulcers Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Ringing In Ears Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Metallic Taste Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Heart Muscle Disease Incidence:
2.0-4.0%*
Severity: SEVERE
Onset: DELAYED
Intestinal Bleeding Incidence:
2.0-9.0%*
Severity: SEVERE
Onset: DELAYED
Fluid Retention Incidence:
5.0-8.0%*
Severity: SEVERE
Onset: DELAYED
Vomiting Incidence:
5.0-16.0%*
Severity: MILD
Onset: EARLY
Muscle Cramps Incidence:
5.0%*
Severity: MILD
Onset: DELAYED
Low Phosphate Level Incidence:
7.0-18.0%*
Severity: SEVERE
Onset: DELAYED
Muscle Pain Incidence:
7.0-13.0%*
Severity: MILD
Onset: EARLY
Fluid Retention Incidence:
>10.0%*
Severity: MODERATE
Onset: DELAYED
Anemia Incidence:
13.0-74.0%*
Severity: SEVERE
Onset: DELAYED
Low Platelet Count Incidence:
22.0-85.0%*
Severity: SEVERE
Onset: DELAYED
Low White Blood Cells Incidence:
29.0-79.0%*
Severity: SEVERE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Sprycel 100mg Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Grapefruit juice and Sprycel 100mg Tablet(Dasatinib)
Grapefruit juice and Dasatinib(Dasatinib)
Do not take Dasatinib with grapefruit or grapefruit juice. Taking Dasatinib with grapefruit or grapefruit juice may increase side effects of Dasatinib. If you accidentally take Dasatinib with grapefruit or grapefruit juice, immediately tell your doctor about any unusual effects.
Moderate Lifestyle Interaction
Marijuana and Sprycel 100mg Tablet(Dasatinib)
Marijuana and Dasatinib(Dasatinib)
Dasatinib can theoretically decrease the elimination of Marijuana, Medical from the body. Side effects from Marijuana, Medical may worsen if you take Dasatinib. You may feel drowsy or more tired. Do not drive or operate machinery until you know how these drugs affect you. Contact your health care provider immediately if you notice slurred speech, confusion, increases heart rate, or palpitations while taking Marijuana, Medical.
Pregnancy & Lactation Information
Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


Learning More About
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Patient Experiences with Sprycel

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