Synercid Lyophilisate For Solution For Injection 150-350Mg Drug Medication Dosage Information
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Synercid: Lyophilisate for solution for injection (150-350mg)

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What is this Medicine?

DALFOPRISTIN; QUINUPRISTIN (dal FOE pris tin; kwi NYOO pris tin) is a streptogramin antibiotic. It is used to treat certain kinds of bacterial infections. It will not work for colds, flu, or other viral infections.

In-Depth Information
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Synercid 500mg Powder for Injection

NDC: 000759051
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Skin And Skin Structure Infections

Sometimes used for but not FDA approved for the following conditions:
Bacteremia, Vancomycin-resistant Enterococci (VRE)

Synercid 500mg Powder for Injection

Reported Side Effects for Synercid 500mg Powder for Injection

Rapid Heart Rate Incidence:
<0.1%*
Severity: SEVERE
Onset: EARLY
Stomach Pain Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Brain Dysfunction Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Intestinal Bleeding Incidence:
<0.2%*
Severity: SEVERE
Onset: DELAYED
Blood In The Urine Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Liver Infection Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Yellow Skin Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Inflamed Pancreas Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Fluid Retention Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Nerve Pain Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Convulsions Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Brain Attack Incidence:
<0.1%*
Severity: SEVERE
Onset: EARLY
Fainting Incidence:
<0.1%*
Severity: MILD
Onset: EARLY
Anaphylactoid Reactions Incidence:
<0.1%*
Severity: SEVERE
Onset: RAPID
Decreased Breathing Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Chest Pain Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Confusion Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Lightheadedness Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Hemolysis Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Excessive Mucle Tone Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Shallow, Slow Breathing Incidence:
<0.1%*
Severity: MODERATE
Onset: RAPID
Hypoxia Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Rash With Pustules Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Muscle Weakness Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Rapid Heart Rate Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Pancytopenia Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Paresthesias Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Peripheral Vasodilation Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Irritated Blood Vessels Incidence:
<2.4%*
Severity: MODERATE
Onset: RAPID
Skin Ulcer Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Rapid Heart Rate Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Yeast Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Constipation Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Bone Pain Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Joint Pain Incidence:
<7.8%*
Severity: MILD
Onset: DELAYED
Shortness Of Breath Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Nervousness Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Fever Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Gout Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Angioedema Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Hemolytic Anemia Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Severe Allergy Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Excessive Sweating Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Low Blood Sugar Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Acute Lung Injury Incidence:
<0.1%*
Severity: SEVERE
Onset: EARLY
Low Blood Sodium Levels Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Low Blood Pressure Incidence:
<0.2%*
Severity: MODERATE
Onset: RAPID
Low Blood Volume Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Inability To Sleep Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Muscle Pain Incidence:
<6.8%*
Severity: MILD
Onset: EARLY
Fluid Around The Heart Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Inflamed Heart Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Fluid Around The Lungs Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Pseudomembranous Colitis Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Mouth Ulcers Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Shaking Incidence:
<0.1%*
Severity: MILD
Onset: EARLY
Hives Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Vaginal Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Elevated Hepatic Enzymes Incidence:
0.4-1.9%*
Severity: MODERATE
Onset: DELAYED
Itching Incidence:
1.5%*
Severity: MILD
Onset: RAPID
Headache Incidence:
1.6%*
Severity: MILD
Onset: EARLY
Blood Clot Incidence:
1.7%*
Severity: SEVERE
Onset: DELAYED
Skin Rash Incidence:
2.5-3.1%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
2.7%*
Severity: MILD
Onset: EARLY
Vomiting Incidence:
2.7-3.7%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
2.8-4.9%*
Severity: MILD
Onset: EARLY
Injection Site Reaction Incidence:
11.6-42.0%*
Severity: MILD
Onset: RAPID
Swelling Incidence:
17.3-18.0%*
Severity: MODERATE
Onset: DELAYED
High Bilirubin Level Incidence:
25.0-34.6%*
Severity: MODERATE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Synercid 500mg Powder for Injection

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Moderate Lifestyle Interaction
Marijuana and Synercid 500mg Powder for Injection(Dalfopristin)
Marijuana and Streptogramins(Dalfopristin)
Dalfopristin; Quinupristin can theoretically decrease the elimination of Marijuana, Medical from the body. Side effects from Marijuana, Medical may worsen if you take Dalfopristin; Quinupristin. You may feel drowsy or more tired. Do not drive or operate machinery until you know how these drugs affect you. Contact your health care provider immediately if you notice slurred speech, confusion, increases heart rate, or palpitations while taking Marijuana, Medical.
Pregnancy & Lactation Information
FIRST Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

SECOND Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

THIRD Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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