Tasigna Oral Capsule 150Mg Drug Medication Dosage Information
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Tasigna: Oral capsule (150mg)

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What is this Medicine?

NILOTINIB (nil OT i nib) is a chemotherapy drug. It targets a specific protein within cancer cells and stops the cells from growing. This medicine is used to treat chronic myelogenous leukemia (CML).

In-Depth Information

Tasigna 150mg Capsule

NDC: 000780592
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Chronic Myelogenous Leukemia (CML)

Storage Information
Store at 77 degrees F; excursions permitted to 59-86 degrees F
Tasigna 150mg Capsule

Reported Side Effects for Tasigna 150mg Capsule

Loss Of Memory Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Vomiting Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Thinning Of Skin Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Bleeding In The Abdomen Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Fluid Retention Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Optic Disc Swelling Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
High White Blood Cells Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Infection Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Blood In The Urine Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Hole In Intestines Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Cholestasis Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Bleeding Incidence:
<1.1%*
Severity: SEVERE
Onset: EARLY
Stomach Pain Incidence:
<3.0%*
Severity: SEVERE
Onset: EARLY
Uncontrolled Urination Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Ringing In Ears Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
High Platelet Count Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Restless Legs Syndrome (RLS) Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
High Pressure In Lungs Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Psoriasis Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Itching Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Light Sensitivity Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Sore Throat Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Inflamed Heart Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Inflamed Optic Nerve Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Eye Pain Incidence:
<0.1%*
Severity: MILD
Onset: EARLY
Muscle Pain Incidence:
<2.0%*
Severity: SEVERE
Onset: EARLY
Low Blood Pressure Incidence:
<0.1%*
Severity: MODERATE
Onset: RAPID
Low Blood Sodium Levels Incidence:
<7.0%*
Severity: SEVERE
Onset: DELAYED
Upset Stomach Incidence:
<2.0%*
Severity: SEVERE
Onset: EARLY
Night Sweats Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Wheezing Incidence:
<0.1%*
Severity: MODERATE
Onset: RAPID
Blood Clot Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Skin Ulcer Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Darkened Skin Patches Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Skin Discoloration Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Kidney Failure Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Skin Rash Incidence:
<2.0%*
Severity: SEVERE
Onset: EARLY
Photosensitivity Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Red Spotted Rash Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Stomach Ulcer Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Hand And Foot Syndrome Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Ear Pain Incidence:
<0.1%*
Severity: MILD
Onset: EARLY
Muscle And/Or Bone Pain Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Heavy Menstrual Period Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Tiredness Incidence:
<0.1%*
Severity: MILD
Onset: EARLY
Hyperkeratosis Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Enlarged Liver Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Vomiting Of Blood Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Deafness Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Rash Of Red Skin Bumps Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Dysphoria Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Dysesthesia Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Lightheadedness Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Double Vision Incidence:
<0.1%*
Severity: MILD
Onset: EARLY
Confusion Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Back Pain Incidence:
<2.0%*
Severity: SEVERE
Onset: DELAYED
Weakness Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Joint Pain Incidence:
<2.0%*
Severity: SEVERE
Onset: DELAYED
Swelling Of The Brain Incidence:
<0.1%*
Severity: SEVERE
Onset: EARLY
Throat Inflammation Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Decreased Appetite Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Angioedema Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Hemorrhoids Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Gum Inflammation Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Upset Stomach Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
High Blood Pressure Incidence:
<2.0%*
Severity: SEVERE
Onset: EARLY
Red Eyes Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Tired Incidence:
<3.0%*
Severity: SEVERE
Onset: EARLY
Fever Incidence:
<2.0%*
Severity: SEVERE
Onset: EARLY
High Uric Acid Level Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Extra Abdominal Fluid Incidence:
<0.7%*
Severity: SEVERE
Onset: DELAYED
Low Calcium Levels Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Constipation Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Low Blood Sugar Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Erythema Multiforme Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Cough Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Inflamed Eyes Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Bone Pain Incidence:
<2.0%*
Severity: SEVERE
Onset: DELAYED
Low Potassium Levels Incidence:
<9.0%*
Severity: SEVERE
Onset: DELAYED
Inflamed Intestine Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Fainting Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Brain Attack Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: EARLY
Yeast Infection Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Nighttime Urination Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Heart Attack Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Eye Irritation Incidence:
0.1-1.0%*
Severity: MILD
Onset: RAPID
Mouth Sores Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Melena Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Causing To Be Hungry Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Blurred Vision Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Chills Incidence:
0.1-1.0%*
Severity: MILD
Onset: RAPID
Painful Urination Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Cyanosis Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: EARLY
Impotence (erectile Dysfunction) Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
High Blood Pressure Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: EARLY
Hyperesthesia Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Bruise Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Engorgement With Blood Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Bruise Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Dehydration Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Gynecomastia Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Heartburn Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Underactive Thyroid Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Breast Pain Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Migraine Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Fluid Around The Heart Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Visual Impairment Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: EARLY
Overactive Thyroid Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Fluid Around The Lungs Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Throat Irritation Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Fluid In Lungs Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: EARLY
Mouth Ulcers Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Shaking Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Urinary Urgency Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Photopsia Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Liver Infection Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Inflamed Stomach Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Intestinal Bleeding Incidence:
0.1-2.9%*
Severity: SEVERE
Onset: DELAYED
Gout Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Bleeding In The Brain Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Yellow Skin Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Heart Failure Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Dry Mouth Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Weight Loss Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Rapid Heart Rate Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: EARLY
Weight Gain Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
High Amylase Levels Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Weakness Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Pancytopenia Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Acne Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Bleeding Within The Eye Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Paresthesias Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Hypoesthesia Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Chest Pain Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: EARLY
Slow Heart Beat Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: RAPID
Increased Urination Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Nervousness Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Rapid Heart Rate Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: RAPID
Low Lymphocytes Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Feeling Sick Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Heart Block Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: EARLY
Irregular Heart Beat Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: EARLY
Irregular Heart Rate Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: EARLY
Nerve Pain Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Inflamed Pancreas Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Low White Blood Cell Counts Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Gas Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Inflamed Hair Follicles Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Increased Blood Fats Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Headache Incidence:
1.0-3.0%*
Severity: SEVERE
Onset: EARLY
Dry Eyes Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Balance Problems Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Hives Incidence:
1.0-10.0%*
Severity: MILD
Onset: RAPID
High Calcium Levels Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
High Cholesterol Incidence:
1.0-28.0%*
Severity: MODERATE
Onset: DELAYED
Excessive Sweating Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
High Potassium Level Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
High Phosphate Levels Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
High Triglycerides Incidence:
1.0-12.0%*
Severity: MODERATE
Onset: DELAYED
Itchy Eyes Incidence:
1.0-10.0%*
Severity: MILD
Onset: RAPID
Inability To Sleep Incidence:
1.0%*
Severity: SEVERE
Onset: EARLY
Low Magnesium Levels Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Flushing Incidence:
1.0-10.0%*
Severity: MILD
Onset: RAPID
Back Pain Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Depression Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Skin Redness Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: EARLY
Eosinophilia Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Elevated Hepatic Enzymes Incidence:
1.0-4.0%*
Severity: SEVERE
Onset: DELAYED
Diabetes Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Hoarseness Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Metallic Taste Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
1.0-3.0%*
Severity: SEVERE
Onset: EARLY
Long Qt Syndrome Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: RAPID
Conjunctivitis Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Chest Pain Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: EARLY
Swollen Eyelids Incidence:
1.0%*
Severity: MILD
Onset: EARLY
Eczema Vaccinatum Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Nose Bleed Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Exfoliative Dermatitis Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Shortness Of Breath Incidence:
2.0%*
Severity: SEVERE
Onset: EARLY
Low Albumin In Blood Incidence:
3.0-4.0%*
Severity: SEVERE
Onset: DELAYED
Fluid Retention Incidence:
3.9%*
Severity: SEVERE
Onset: DELAYED
High Bilirubin Level Incidence:
4.0-9.0%*
Severity: SEVERE
Onset: DELAYED
Anemia Incidence:
4.0-27.0%*
Severity: SEVERE
Onset: DELAYED
Increased Blood Sugar Incidence:
6.0-12.0%*
Severity: SEVERE
Onset: DELAYED
Low Phosphate Level Incidence:
8.0-17.0%*
Severity: SEVERE
Onset: DELAYED
Low Platelet Count Incidence:
10.0-42.0%*
Severity: SEVERE
Onset: DELAYED
Low White Blood Cells Incidence:
12.0-42.0%*
Severity: SEVERE
Onset: DELAYED
Dry Skin Incidence:
12.0%*
Severity: MILD
Onset: DELAYED
Flu Incidence:
13.0%*
Severity: MILD
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Tasigna 150mg Capsule

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Severe Lifestyle Interaction
Grapefruit juice and Tasigna 150mg Capsule(Nilotinib)
Grapefruit juice and Nilotinib(Nilotinib)
Do not take Nilotinib with grapefruit, grapefruit juice, or supplements that contain grapefruit extract. Taking Nilotinib with grapefruit or grapefruit juice may increase side effects of Nilotinib. If you accidentally take Nilotinib with grapefruit or grapefruit juice, immediately tell your doctor about any unusual effects.
Severe Lifestyle Interaction
Food and Tasigna 150mg Capsule(Nilotinib)
Food and Nilotinib(Nilotinib)
Nilotinib needs to be taken at least 1 hour before a meal or 2 hours after a meal. Do not take Nilotinib with food. Taking Nilotinib with food may increase side effects. Tell your doctor about any unusual effects, such as irregular or fast heartbeat, chest pain, palpitations, or unusual fatigue, weakness or fever.
Pregnancy & Lactation Information
FIRST Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

SECOND Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

THIRD Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


Learning More About
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Patient Experiences with Tasigna

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