Thymoglobulin Powder For Solution For Injection 25Mg Drug Medication Dosage Information
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Thymoglobulin: Powder for solution for injection (25mg)

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What is this Medicine?

ANTI-THYMOCYTE IMMUNE GLOBULIN (an tee THI mo cite im MUNE GLOB yoo lin) weakens the body's immune system. This medicine is used to treat kidney transplant rejection.

In-Depth Information
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Thymoglobulin 25mg Powder for Injection

NDC: 620530534
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Kidney Transplant Rejection

Sometimes used for but not FDA approved for the following conditions:
Heart Transplant Rejection Prophylaxis, Kidney Transplant Rejection Prophylaxis, Heart Transplant Rejection, Myelodysplastic Syndrome (MDS), Stem Cell Transplant Preparation, Graft-versus-host Disease (GVHD) Prophylaxis, Graft-versus-host Disease (GVHD), Aplastic Anemia

Storage Information
Reconstituted product may be stored at room temperature for up to 24 hours but is not recommended
Thymoglobulin 25mg Powder for Injection

Reported Side Effects for Thymoglobulin 25mg Powder for Injection

Heart Attack Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Convulsions Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Hole In Intestines Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Intestinal Bleeding Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Vomiting Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Infusion-related Reactions Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Back Pain Incidence:
<10.0%*
Severity: MILD
Onset: DELAYED
Fluid In Lungs Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Chest Pain Incidence:
<10.0%*
Severity: MODERATE
Onset: EARLY
Muscle Pain Incidence:
<10.0%*
Severity: MILD
Onset: EARLY
Low Blood Pressure Incidence:
<5.0%*
Severity: MODERATE
Onset: RAPID
Back Pain Incidence:
<10.0%*
Severity: MODERATE
Onset: DELAYED
Hemolysis Incidence:
<5.0%*
Severity: MODERATE
Onset: EARLY
Hemolytic Anemia Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Heart Failure Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Injection Site Reaction Incidence:
<5.0%*
Severity: MILD
Onset: RAPID
Tiredness Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Swelling Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Paresthesias Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Irritated Blood Vessels Incidence:
<5.0%*
Severity: MODERATE
Onset: RAPID
Weakness Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Severe Allergy Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Acute Lung Injury Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Eosinophilia Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Secondary Malignancy Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Post-transplant Lymphoproliferative Disorder (PTLD) Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Joint Pain Incidence:
1.0-50.0%*
Severity: MILD
Onset: DELAYED
Low White Blood Cells Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Yeast Infection Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Feeling Sick Incidence:
4.0-14.0%*
Severity: MILD
Onset: EARLY
Serum Sickness Incidence:
5.0-85.0%*
Severity: SEVERE
Onset: DELAYED
Lightheadedness Incidence:
9.0-25.0%*
Severity: MILD
Onset: EARLY
Hives Incidence:
12.0%*
Severity: MILD
Onset: RAPID
Itching Incidence:
12.0%*
Severity: MILD
Onset: RAPID
Skin Rash Incidence:
12.0-27.0%*
Severity: MILD
Onset: EARLY
High Potassium Level Incidence:
18.5-26.8%*
Severity: SEVERE
Onset: DELAYED
Shortness Of Breath Incidence:
19.8-28.0%*
Severity: MODERATE
Onset: EARLY
Rapid Heart Rate Incidence:
23.5-26.8%*
Severity: MODERATE
Onset: RAPID
Infection Incidence:
23.5-30.5%*
Severity: MILD
Onset: DELAYED
Upset Stomach Incidence:
>25.0%*
Severity: MILD
Onset: EARLY
Stomach Pain Incidence:
>25.0%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
>25.0%*
Severity: MILD
Onset: EARLY
Weakness Incidence:
26.8-32.1%*
Severity: MILD
Onset: DELAYED
High Blood Pressure Incidence:
28.4-36.6%*
Severity: MODERATE
Onset: EARLY
Low White Blood Cell Counts Incidence:
29.6-57.3%*
Severity: MODERATE
Onset: DELAYED
Headache Incidence:
34.6-40.2%*
Severity: MILD
Onset: EARLY
Low Platelet Count Incidence:
36.6-44.4%*
Severity: MODERATE
Onset: DELAYED
Chills Incidence:
43.2-57.3%*
Severity: MILD
Onset: RAPID
Fever Incidence:
63.0%*
Severity: MILD
Onset: EARLY
Antibody Formation Incidence:
68.0-78.0%*
Severity: MODERATE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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