Tikosyn Oral Capsule 125Mcg Drug Medication Dosage Information
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Tikosyn: Oral capsule (125mcg)

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Drug Image file DrugItem_2397.JPG
Tikosyn 125mcg Cap
Pfizer US Pharmaceuticals
Pill Identification: Pfizer TKN 125 

What is this Medicine?

DOFETILIDE (doe FET il ide) is an antiarrhythmic drug. It helps make your heart beat regularly. This medicine also helps to slow rapid heartbeats.

CVS Pharmacy Patient Statistics for Tikosyn: Oral capsule(125mcg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information

Tikosyn 125mcg Capsule

NDC: 000695800
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Atrial Flutter, Atrial Fibrillation

Storage Information
Store at room temperature (between 59 to 86 degrees F)
Protect from moisture
Avoid excessive humidity
Tikosyn 125mcg Capsule
Drug Image file DrugItem_2397.JPG
Pfizer US Pharmaceuticals
Pill Identification: Pfizer TKN 125 
Shape: capsule
Color: orange,white

Reported Side Effects for Tikosyn 125mcg Capsule

Heart Attack Incidence:
<2.0%*
Severity: SEVERE
Onset: DELAYED
Infection Incidence:
<7.0%*
Severity: MILD
Onset: DELAYED
Brain Attack Incidence:
<2.0%*
Severity: SEVERE
Onset: EARLY
Migraine Incidence:
<2.0%*
Severity: MODERATE
Onset: EARLY
Fainting Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Swelling Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Elevated Hepatic Enzymes Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Cough Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Suddenly Stopped Heart Incidence:
<2.0%*
Severity: SEVERE
Onset: EARLY
Slow Heart Beat Incidence:
<2.0%*
Severity: SEVERE
Onset: RAPID
Angioedema Incidence:
<2.0%*
Severity: SEVERE
Onset: RAPID
Torsade De Pointes Incidence:
0.3-3.3%*
Severity: SEVERE
Onset: RAPID
Rapid Heart Rate Incidence:
0.3-0.4%*
Severity: SEVERE
Onset: EARLY
Heart Block Incidence:
0.4-1.5%*
Severity: SEVERE
Onset: EARLY
Diaphoresis Incidence:
>2.0%*
Severity: MILD
Onset: EARLY
Weakness Incidence:
>2.0%*
Severity: MILD
Onset: DELAYED
Rapid Heart Rate Incidence:
>2.0%*
Severity: MODERATE
Onset: EARLY
Fluid Retention Incidence:
>2.0%*
Severity: MODERATE
Onset: DELAYED
High Blood Pressure Incidence:
>2.0%*
Severity: MODERATE
Onset: EARLY
Joint Pain Incidence:
>2.0%*
Severity: MILD
Onset: DELAYED
Nervousness Incidence:
>2.0%*
Severity: MILD
Onset: DELAYED
Chest Pain Incidence:
>2.0%*
Severity: MODERATE
Onset: EARLY
Rapid Heart Rate Incidence:
2.6-3.3%*
Severity: SEVERE
Onset: EARLY
Stomach Pain Incidence:
3.0%*
Severity: MILD
Onset: EARLY
Back Pain Incidence:
3.0%*
Severity: MILD
Onset: DELAYED
Loose Stools Incidence:
3.0%*
Severity: MILD
Onset: EARLY
Skin Rash Incidence:
3.0%*
Severity: MILD
Onset: EARLY
Flu Incidence:
4.0%*
Severity: MILD
Onset: DELAYED
Inability To Sleep Incidence:
4.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
5.0%*
Severity: MILD
Onset: EARLY
Shortness Of Breath Incidence:
6.0%*
Severity: MODERATE
Onset: EARLY
Lightheadedness Incidence:
8.0%*
Severity: MILD
Onset: EARLY
Chest Pain Incidence:
10.0%*
Severity: MODERATE
Onset: EARLY
Headache Incidence:
11.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Tikosyn 125mcg Capsule

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Grapefruit juice and Tikosyn 125mcg Capsule(Dofetilide)
Grapefruit juice and Dofetilide(Dofetilide)
Use caution when taking grapefruit juice with Dofetilide since it can increase the risk of a dangerous change in heartbeat or heart rhythm. Contact your prescriber immediately if you experience chest pain, dizziness, fainting or falling spells, palpitations, shortness of breath, or a change in your usual heart beat (fast, slow, or irregular heart beat) while taking Dofetilide.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


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Patient Experiences with Tikosyn

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