Tramadol Oral Tablet, Extended Release 100Mg Drug Medication Dosage Information
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Tramadol: Oral tablet, extended release (100mg)

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Pill Identification: PP 100 
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Tramadol 100mg ER Tab
Par Pharmaceuticals, formerly Anchen Pharmaceuticals
Pill Identification: A221 

What is this Medicine?

TRAMADOL (TRA ma dole) is a pain reliever. It is used to treat moderate to severe pain in adults.

In-Depth Information
Select a Medication

Tramadol Hydrochloride 100mg Extended-Release Tablet

NDC: 103700221
  • Prescription Required
  • Federally Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Severe Pain, Moderate Pain

Sometimes used for but not FDA approved for the following conditions:
Bone Pain, Dental Pain

Storage Information
Store at controlled room temperature (between 68 and 77 degrees F)
Tramadol Hydrochloride 100mg Extended-Release Tablet
Drug Image file DrugItem_15521.JPG
Par Pharmaceuticals, formerly Anchen Pharmaceuticals
Pill Identification: A221 
Shape: round
Color: white

Reported Side Effects for Tramadol Hydrochloride 100mg Extended-Release Tablet

Elated Mood Incidence:
<14.0%*
Severity: MODERATE
Onset: EARLY
Emotional Lability Incidence:
<14.0%*
Severity: MILD
Onset: EARLY
Diaphoresis Incidence:
<9.0%*
Severity: MILD
Onset: EARLY
Incoordination Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Weakness Incidence:
<12.0%*
Severity: MILD
Onset: DELAYED
Loss Of Memory Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Fainting Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Thoughts Of Suicide Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Convulsions Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Inflamed Pancreas Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Liver Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Intestinal Bleeding Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Difficulty Swallowing Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Night Sweats Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Yawning Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Serotonin Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Paresthesias Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Pale Skin Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Feeling Sick Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Decreased Sexual Desire Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Irritability Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Impotence (erectile Dysfunction) Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Decreased Thinking Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Excessive Mucle Tone Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Hyperkinesis Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Liver Failure Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Hallucinations Incidence:
<14.0%*
Severity: MODERATE
Onset: EARLY
Heartburn Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Flushing Incidence:
<15.8%*
Severity: MILD
Onset: RAPID
Postural Low Blood Pressure Incidence:
<5.4%*
Severity: MODERATE
Onset: DELAYED
Nervousness Incidence:
<14.0%*
Severity: MILD
Onset: DELAYED
Slow Heart Beat Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Low Blood Pressure Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
High Blood Pressure Incidence:
<5.0%*
Severity: MODERATE
Onset: EARLY
Loose Stools Incidence:
<10.0%*
Severity: MILD
Onset: EARLY
Depression Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Tooth Pain Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Shaking Incidence:
<14.0%*
Severity: MILD
Onset: EARLY
Mouth Ulcers Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Distressed Incidence:
<14.0%*
Severity: MILD
Onset: EARLY
Rapid Heart Rate Incidence:
0.5-0.9%*
Severity: MODERATE
Onset: EARLY
Balance Problems Incidence:
0.5-33.0%*
Severity: MILD
Onset: EARLY
Gas Incidence:
0.5-4.9%*
Severity: MILD
Onset: EARLY
Heart Attack Incidence:
0.5-0.9%*
Severity: SEVERE
Onset: DELAYED
Rapid Heart Rate Incidence:
0.5-0.9%*
Severity: MODERATE
Onset: RAPID
Decreased Appetite Incidence:
0.7-5.9%*
Severity: MILD
Onset: DELAYED
Peripheral Vasodilation Incidence:
1.0-4.9%*
Severity: MODERATE
Onset: RAPID
Cough Incidence:
1.0-4.9%*
Severity: MILD
Onset: DELAYED
Restlessness Incidence:
1.0-4.9%*
Severity: MILD
Onset: EARLY
Weakness Incidence:
1.0-4.9%*
Severity: MILD
Onset: EARLY
Visual Impairment Incidence:
1.0-4.9%*
Severity: SEVERE
Onset: EARLY
Stomach Pain Incidence:
1.0-4.9%*
Severity: MILD
Onset: EARLY
Dry Mouth Incidence:
1.0-13.1%*
Severity: MILD
Onset: EARLY
Sneezing Incidence:
1.0-4.9%*
Severity: MILD
Onset: EARLY
Runny Nose Incidence:
1.0-4.9%*
Severity: MILD
Onset: EARLY
Blurred Vision Incidence:
1.0-4.9%*
Severity: MODERATE
Onset: EARLY
Confusion Incidence:
1.0-4.9%*
Severity: MODERATE
Onset: EARLY
Stuffy Nose Incidence:
1.0-4.9%*
Severity: MILD
Onset: EARLY
Inability To Sleep Incidence:
1.0-10.9%*
Severity: MILD
Onset: EARLY
Hot Flashes Incidence:
1.0-4.9%*
Severity: MODERATE
Onset: EARLY
Tired Incidence:
1.0-4.9%*
Severity: MILD
Onset: EARLY
Hypoesthesia Incidence:
1.0-4.9%*
Severity: MILD
Onset: DELAYED
Upset Stomach Incidence:
1.0-13.0%*
Severity: MILD
Onset: EARLY
Tiredness Incidence:
1.0-4.9%*
Severity: MILD
Onset: EARLY
Miosis Incidence:
1.0-4.9%*
Severity: MILD
Onset: EARLY
Itching Incidence:
3.0-11.9%*
Severity: MILD
Onset: RAPID
Vomiting Incidence:
3.0-17.0%*
Severity: MILD
Onset: EARLY
Drowsiness Incidence:
5.0-25.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
7.0-33.0%*
Severity: MILD
Onset: EARLY
Constipation Incidence:
9.3-46.0%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
13.0-40.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Tramadol Hydrochloride 100mg Extended-Release Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Alcohol and Tramadol Hydrochloride 100mg Extended-Release Tablet(Tramadol Hydrochloride)
Alcohol and CNS Depressants(Tramadol Hydrochloride)
Avoid alcohol-containing drinks while taking this medicine. Using this drug along with alcohol can lead to serious side effects. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery until you know how this drug affects you, and especially if you are drinking alcohol-containing beverages. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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