Trisenox Solution For Injection 1Mg Drug Medication Dosage Information
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Trisenox: Solution for injection (1mg)

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What is this Medicine?

ARSENIC TRIOXIDE (AR se nik trye OX ide) is a chemotherapy drug. It slows the growth of cancer cells. This medicine is used to treat acute promyelocytic leukemia (APL).

In-Depth Information
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Trisenox 1mg/ml Solution for Injection

NDC: 634590600
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Acute Promyelocytic Leukemia (APL)

Storage Information
Protect from freezing
Store at 77 degrees F; excursions permitted to 59-86 degrees F
Trisenox 1mg/ml Solution for Injection

Reported Side Effects for Trisenox 1mg/ml Solution for Injection

Heart Block Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Inability To Sleep Incidence:
3.0%*
Severity: SEVERE
Onset: EARLY
Elevated Hepatic Enzymes Incidence:
3.0-5.0%*
Severity: SEVERE
Onset: DELAYED
Headache Incidence:
3.0%*
Severity: SEVERE
Onset: EARLY
Itching Incidence:
3.0%*
Severity: SEVERE
Onset: RAPID
High White Blood Cells Incidence:
3.0%*
Severity: SEVERE
Onset: DELAYED
Back Pain Incidence:
3.0%*
Severity: SEVERE
Onset: DELAYED
Constipation Incidence:
3.0%*
Severity: SEVERE
Onset: DELAYED
Ringing In Ears Incidence:
5.0%*
Severity: MILD
Onset: DELAYED
Confusion Incidence:
5.0%*
Severity: MODERATE
Onset: EARLY
Uncontrolled Urination Incidence:
5.0%*
Severity: MODERATE
Onset: EARLY
Sore Throat Incidence:
5.0%*
Severity: MILD
Onset: DELAYED
Paresthesias Incidence:
5.0%*
Severity: SEVERE
Onset: DELAYED
Muscle Pain Incidence:
5.0%*
Severity: SEVERE
Onset: EARLY
Electrolyte Imbalance Incidence:
5.0%*
Severity: MODERATE
Onset: DELAYED
Bleeding Incidence:
5.0%*
Severity: SEVERE
Onset: EARLY
Low Blood Pressure Incidence:
5.0%*
Severity: SEVERE
Onset: RAPID
Weakness Incidence:
5.0%*
Severity: SEVERE
Onset: EARLY
Infection Incidence:
5.0-20.0%*
Severity: MILD
Onset: DELAYED
Yeast Infection Incidence:
5.0%*
Severity: MODERATE
Onset: DELAYED
Coma Incidence:
5.0%*
Severity: SEVERE
Onset: EARLY
Anemia Incidence:
5.0%*
Severity: SEVERE
Onset: DELAYED
Irregular Heart Rate Incidence:
5.0%*
Severity: SEVERE
Onset: EARLY
Tired Incidence:
5.0%*
Severity: SEVERE
Onset: EARLY
Fever Incidence:
5.0%*
Severity: SEVERE
Onset: EARLY
Distressed Incidence:
5.0%*
Severity: MILD
Onset: EARLY
Irregular Heart Beat Incidence:
5.0%*
Severity: SEVERE
Onset: EARLY
Night Sweats Incidence:
8.0%*
Severity: MILD
Onset: EARLY
Joint Pain Incidence:
8.0%*
Severity: SEVERE
Onset: DELAYED
Enlarged Lymph Nodes Incidence:
8.0%*
Severity: MODERATE
Onset: DELAYED
Ear Pain Incidence:
8.0%*
Severity: MILD
Onset: EARLY
Intestinal Bleeding Incidence:
8.0%*
Severity: SEVERE
Onset: DELAYED
Convulsions Incidence:
8.0%*
Severity: SEVERE
Onset: DELAYED
Disseminated Intravascular Coagulation (DIC) Incidence:
8.0%*
Severity: SEVERE
Onset: DELAYED
Dry Mouth Incidence:
8.0%*
Severity: MILD
Onset: EARLY
Coughing Up Blood Incidence:
8.0%*
Severity: MODERATE
Onset: DELAYED
Dry Eyes Incidence:
8.0%*
Severity: MILD
Onset: EARLY
Drowsiness Incidence:
8.0%*
Severity: MILD
Onset: EARLY
Hives Incidence:
8.0%*
Severity: MILD
Onset: RAPID
Low Blood Sugar Incidence:
8.0%*
Severity: MODERATE
Onset: EARLY
Fecal Incontinence Incidence:
8.0%*
Severity: MODERATE
Onset: EARLY
Red Spotted Rash Incidence:
8.0%*
Severity: MILD
Onset: DELAYED
Kidney Failure Incidence:
8.0%*
Severity: SEVERE
Onset: DELAYED
Mouth Ulcers Incidence:
>8.0%*
Severity: MODERATE
Onset: DELAYED
Darkened Skin Patches Incidence:
8.0%*
Severity: MILD
Onset: DELAYED
Rapid Breathing Incidence:
8.0%*
Severity: MODERATE
Onset: EARLY
Weight Loss Incidence:
8.0%*
Severity: MILD
Onset: DELAYED
Bone Pain Incidence:
10.0%*
Severity: SEVERE
Onset: DELAYED
Hypoxia Incidence:
10.0%*
Severity: SEVERE
Onset: EARLY
Injection Site Reaction Incidence:
10.0-20.0%*
Severity: MILD
Onset: RAPID
Flushing Incidence:
10.0%*
Severity: MILD
Onset: RAPID
Blurred Vision Incidence:
10.0%*
Severity: MODERATE
Onset: EARLY
Eye Irritation Incidence:
10.0%*
Severity: MILD
Onset: RAPID
Pale Skin Incidence:
10.0%*
Severity: MILD
Onset: EARLY
Stomach Pain Incidence:
10.0%*
Severity: SEVERE
Onset: EARLY
Rapid Heart Rate Incidence:
10.0%*
Severity: MODERATE
Onset: EARLY
Upset Stomach Incidence:
10.0%*
Severity: MILD
Onset: EARLY
Shortness Of Breath Incidence:
10.0%*
Severity: SEVERE
Onset: EARLY
Low White Blood Cells Incidence:
10.0%*
Severity: MODERATE
Onset: DELAYED
High Blood Pressure Incidence:
10.0%*
Severity: MODERATE
Onset: EARLY
Low Calcium Levels Incidence:
10.0%*
Severity: MODERATE
Onset: DELAYED
Weight Gain Incidence:
13.0%*
Severity: MILD
Onset: DELAYED
Wheezing Incidence:
13.0%*
Severity: MODERATE
Onset: RAPID
Skin Redness Incidence:
13.0%*
Severity: MODERATE
Onset: EARLY
Low Magnesium Levels Incidence:
13.0%*
Severity: SEVERE
Onset: DELAYED
Low Potassium Levels Incidence:
13.0%*
Severity: SEVERE
Onset: DELAYED
Excessive Sweating Incidence:
13.0%*
Severity: MILD
Onset: DELAYED
Vaginal Bleeding Incidence:
13.0%*
Severity: MODERATE
Onset: DELAYED
Low Platelet Count Incidence:
13.0%*
Severity: SEVERE
Onset: DELAYED
Shaking Incidence:
13.0%*
Severity: MILD
Onset: EARLY
Increased Blood Sugar Incidence:
13.0%*
Severity: SEVERE
Onset: DELAYED
Dry Skin Incidence:
15.0%*
Severity: MILD
Onset: DELAYED
High Potassium Level Incidence:
18.0%*
Severity: SEVERE
Onset: DELAYED
Bruise Incidence:
20.0%*
Severity: MILD
Onset: DELAYED
Fluid Around The Lungs Incidence:
20.0%*
Severity: SEVERE
Onset: DELAYED
Sinus Infection Incidence:
20.0%*
Severity: MILD
Onset: DELAYED
Depression Incidence:
20.0%*
Severity: MODERATE
Onset: DELAYED
Decreased Appetite Incidence:
23.0%*
Severity: MILD
Onset: DELAYED
Lightheadedness Incidence:
23.0%*
Severity: MILD
Onset: EARLY
Nose Bleed Incidence:
25.0%*
Severity: MILD
Onset: DELAYED
Chest Pain Incidence:
25.0%*
Severity: MODERATE
Onset: EARLY
Nervousness Incidence:
30.0%*
Severity: MILD
Onset: DELAYED
Chills Incidence:
38.0%*
Severity: MILD
Onset: RAPID
Swelling Incidence:
40.0%*
Severity: MODERATE
Onset: DELAYED
Long Qt Syndrome Incidence:
40.0%*
Severity: MODERATE
Onset: RAPID
Loose Stools Incidence:
53.0%*
Severity: MILD
Onset: EARLY
Rapid Heart Rate Incidence:
55.0%*
Severity: MODERATE
Onset: RAPID
Vomiting Incidence:
58.0%*
Severity: MILD
Onset: EARLY
Cough Incidence:
65.0%*
Severity: MILD
Onset: DELAYED
Upset Stomach Incidence:
75.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Pregnancy & Lactation Information
FIRST Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

SECOND Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

THIRD Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


Learning More About
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  • Find additional patient usage statistics
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