Velcade Powder For Solution For Injection 3.5Mg Drug Medication Dosage Information
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Velcade: Powder for solution for injection (3.5mg)

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What is this Medicine?

BORTEZOMIB (bor TEZ oh mib) is a medicine that targets proteins in cancer cells and stops the cancer cells from growing. It is used to treat multiple myeloma and mantle-cell lymphoma.

In-Depth Information

Velcade 3.5mg Powder for Injection

NDC: 630200049
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Mantle Cell Lymphoma (MCL), Multiple Myeloma

Sometimes used for but not FDA approved for the following conditions:
Non-Hodgkin's Lymphoma (NHL)

Storage Information
Protect from light
Store in carton
Reconstituted product is stable for up to 8 hours at room temperature (77 degrees F)
Store at 77 degrees F; excursions permitted to 59-86 degrees F
Velcade 3.5mg Powder for Injection

Reported Side Effects for Velcade 3.5mg Powder for Injection

Vomiting Incidence:
<4.0%*
Severity: SEVERE
Onset: EARLY
Fainting Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Long Qt Syndrome Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Fluid Retention Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Increased Blood Sugar Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Brain Dysfunction Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Fluid Around The Heart Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Stomach Pain Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Upset Stomach Incidence:
<3.0%*
Severity: SEVERE
Onset: EARLY
Lyell'S Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Skin Rash Incidence:
<3.0%*
Severity: SEVERE
Onset: EARLY
Lightheadedness Incidence:
<3.0%*
Severity: SEVERE
Onset: EARLY
High Blood Pressure Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Heart Failure Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Headache Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Fever Incidence:
<3.0%*
Severity: SEVERE
Onset: EARLY
Constipation Incidence:
<2.0%*
Severity: SEVERE
Onset: DELAYED
Decreased Appetite Incidence:
<2.0%*
Severity: SEVERE
Onset: DELAYED
Hair Loss Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Fluid In Lungs Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Postural Low Blood Pressure Incidence:
<3.0%*
Severity: SEVERE
Onset: DELAYED
Inability To Sleep Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Low Blood Pressure Incidence:
<3.0%*
Severity: SEVERE
Onset: RAPID
Bleeding Incidence:
1.0%*
Severity: SEVERE
Onset: EARLY
Anemia Incidence:
1.0-13.0%*
Severity: SEVERE
Onset: DELAYED
Hypoesthesia Incidence:
1.0%*
Severity: SEVERE
Onset: DELAYED
Paresthesias Incidence:
1.0-2.0%*
Severity: SEVERE
Onset: DELAYED
Mouth Ulcers Incidence:
1.0%*
Severity: SEVERE
Onset: DELAYED
Weakness Incidence:
2.0-3.0%*
Severity: SEVERE
Onset: EARLY
Weakness Incidence:
3.0-5.0%*
Severity: SEVERE
Onset: DELAYED
Low White Blood Cells Incidence:
3.0-83.0%*
Severity: SEVERE
Onset: DELAYED
Infection Incidence:
5.0%*
Severity: SEVERE
Onset: DELAYED
Loose Stools Incidence:
5.0-9.0%*
Severity: SEVERE
Onset: EARLY
Low Platelet Count Incidence:
6.0-57.0%*
Severity: SEVERE
Onset: DELAYED
Tired Incidence:
6.0-10.0%*
Severity: SEVERE
Onset: EARLY
Nerve Pain Incidence:
8.0-13.0%*
Severity: SEVERE
Onset: DELAYED
Itching Incidence:
10.0%*
Severity: MILD
Onset: RAPID
Joint Pain Incidence:
11.0-17.0%*
Severity: MILD
Onset: DELAYED
Bone Pain Incidence:
11.0-16.0%*
Severity: MODERATE
Onset: DELAYED
Back Pain Incidence:
13.0-17.0%*
Severity: MILD
Onset: DELAYED
Low Lymphocytes Incidence:
19.0-25.0%*
Severity: SEVERE
Onset: DELAYED
Low White Blood Cell Counts Incidence:
21.0-43.0%*
Severity: SEVERE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Velcade 3.5mg Powder for Injection

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Minor Lifestyle Interaction
Grapefruit juice and Velcade 3.5mg Powder for Injection(Bortezomib)
Grapefruit juice and Bortezomib(Bortezomib)
In theory, Tobacco smoking may increase the risk of serious lung side effects of Bleomycin. Talk to your prescriber about stopping Tobacco smoking if you are receiving Bleomycin treatment. Discuss any new or worsening side effects, such as a persistent, non-productive cough or shortness of breath, with your health care provider while you are receiving Bleomycin treatment.
Pregnancy & Lactation Information
FIRST Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

SECOND Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

THIRD Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


Learning More About
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