Vinorelbine Solution For Injection 10Mg Drug Medication Dosage Information
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Vinorelbine: Solution for injection (10mg)

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What is this Medicine?

VINORELBINE (vi NOR el been) is a chemotherapy drug. It targets fast dividing cells, like cancer cells, and causes these cells to die. This medicine is used to treat cancer, like lung cancer.

In-Depth Information
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Vinorelbine Tartrate 10mg/ml Solution for Injection

NDC: 459630607
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Non-small Cell Lung Cancer (NSCLC)

Sometimes used for but not FDA approved for the following conditions:
Breast Cancer, Desmoid Tumor, Hodgkin's Disease, Ovarian Cancer, Head And Neck Cancer

Storage Information
Refrigerate (between 36 and 46 degrees F)
Protect from light
Store in original container
Do not freeze
Vinorelbine Tartrate 10mg/ml Solution for Injection

Reported Side Effects for Vinorelbine Tartrate 10mg/ml Solution for Injection

Balance Problems Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Heart Attack Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Nerve Pain Incidence:
<7.0%*
Severity: SEVERE
Onset: DELAYED
Breathing Difficulties Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Lightheadedness Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Elevated Hepatic Enzymes Incidence:
<6.0%*
Severity: SEVERE
Onset: DELAYED
Hyperesthesia Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Injection Site Reaction Incidence:
<2.5%*
Severity: SEVERE
Onset: RAPID
Paresthesias Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Irritated Blood Vessels Incidence:
<3.0%*
Severity: SEVERE
Onset: RAPID
Skin Rash Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Tired Incidence:
<12.0%*
Severity: SEVERE
Onset: EARLY
Joint Pain Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Painful Bloody Urine Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
High Bilirubin Level Incidence:
<7.0%*
Severity: SEVERE
Onset: DELAYED
Hair Loss Incidence:
<7.5%*
Severity: SEVERE
Onset: DELAYED
Muscle Pain Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Acute Lung Injury Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
SIADH Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Low Platelet Count Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Anemia Incidence:
1.0-24.0%*
Severity: SEVERE
Onset: DELAYED
Weight Loss Incidence:
1.0%*
Severity: SEVERE
Onset: DELAYED
Fever Incidence:
1.0%*
Severity: SEVERE
Onset: EARLY
Loose Stools Incidence:
1.5-2.0%*
Severity: SEVERE
Onset: EARLY
Vomiting Incidence:
2.0-30.0%*
Severity: SEVERE
Onset: EARLY
Weakness Incidence:
2.0%*
Severity: SEVERE
Onset: EARLY
Upset Stomach Incidence:
2.0-30.0%*
Severity: SEVERE
Onset: EARLY
Shortness Of Breath Incidence:
3.0%*
Severity: SEVERE
Onset: EARLY
Constipation Incidence:
3.0%*
Severity: SEVERE
Onset: DELAYED
Deafness Incidence:
4.0%*
Severity: SEVERE
Onset: DELAYED
Chest Pain Incidence:
5.0%*
Severity: MODERATE
Onset: EARLY
Tiredness Incidence:
12.0%*
Severity: SEVERE
Onset: EARLY
Feeling Sick Incidence:
12.0%*
Severity: SEVERE
Onset: EARLY
Low White Blood Cell Counts Incidence:
12.0-58.0%*
Severity: SEVERE
Onset: DELAYED
Metallic Taste Incidence:
17.0%*
Severity: MILD
Onset: EARLY
Low White Blood Cells Incidence:
36.0-82.0%*
Severity: SEVERE
Onset: DELAYED
Decreased Appetite Incidence:
46.0%*
Severity: MILD
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Vinorelbine Tartrate 10mg/ml Solution for Injection

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Grapefruit juice and Vinorelbine Tartrate 10mg/ml Solution for Injection(Vinorelbine Tartrate)
Grapefruit juice and Vinorelbine(Vinorelbine Tartrate)
Do not take Vinorelbine and Grapefruit Juice together without talking to your health care provider. The risk of side effects from Vinorelbine is increased if Grapefruit Juice is also taken. Notify your health care provider immediately if you notice new or worsening constipation, stomach or abdominal pain, tingling in fingers and/or toes, or inability to pick-up items with your fingers.
Pregnancy & Lactation Information
FIRST Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

SECOND Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

THIRD Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


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