Voraxaze Powder For Solution For Injection 1000iu Drug Medication Dosage Information
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VORAXAZE: Powder for solution for injection (1000IU)

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What is this Medicine?

GLUCARPIDASE (gloo KAR pi dayz) is an enzyme that helps to lower the amount of methotrexate in the body. This medicine treats toxic amounts of methotrexate in patients with kidney problems.

In-Depth Information

Voraxaze 1000units Powder for Injection

NDC: 506330210
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Methotrexate Toxicity

Storage Information
Store unreconstituted product in refrigerator (36 to 46 degrees F)
Discard product if it contains particulate matter, is cloudy, or discolored
Do not freeze
Discard unused portion. Do not store for later use.
Reconstituted product should be refrigerated (36 to 46 degrees F) and used within 4 hours if not used immediately
Voraxaze 1000units Powder for Injection

Reported Side Effects for Voraxaze 1000units Powder for Injection

Loose Stools Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
High Blood Pressure Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Shaking Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Blurred Vision Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Flushing Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Skin Rash Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Throat Irritation Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Headache Incidence:
1.0%*
Severity: MILD
Onset: EARLY
Low Blood Pressure Incidence:
1.0%*
Severity: MODERATE
Onset: RAPID
Vomiting Incidence:
2.0%*
Severity: MILD
Onset: EARLY
Paresthesias Incidence:
2.0%*
Severity: MILD
Onset: DELAYED
Upset Stomach Incidence:
2.0%*
Severity: MILD
Onset: EARLY
Antibody Formation Incidence:
17.0%*
Severity: MODERATE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


Learning More About
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Patient Experiences with VORAXAZE

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