Vpriv Powder For Solution For Injection 400U Drug Medication Dosage Information
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VPRIV: Powder for solution for injection (400U)

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What is this Medicine?

Velaglucerase alfa is a man-made form of an enzyme that is missing in patients with Gaucher's disease. It is used to treat the symptoms of Gaucher's disease. It is not a cure.

In-Depth Information

VPRIV 400unit Powder for Injection

NDC: 540920701
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Gaucher's Disease

Storage Information
Refrigerate (between 36 and 46 degrees F)
Protect from light
Discard unused portion. Do not store for later use.
Do not freeze
VPRIV 400unit Powder for Injection

Reported Side Effects for VPRIV 400unit Powder for Injection

Antibody Formation Incidence:
1.8%*
Severity: MODERATE
Onset: DELAYED
High Blood Pressure Incidence:
>2.0%*
Severity: MODERATE
Onset: EARLY
Low Blood Pressure Incidence:
>2.0%*
Severity: MODERATE
Onset: RAPID
Hives Incidence:
>2.0%*
Severity: MILD
Onset: RAPID
Rapid Heart Rate Incidence:
>2.0%*
Severity: MODERATE
Onset: RAPID
Skin Rash Incidence:
>2.0%*
Severity: MILD
Onset: EARLY
Bone Pain Incidence:
>2.0%*
Severity: MODERATE
Onset: DELAYED
Flushing Incidence:
>2.0%*
Severity: MILD
Onset: RAPID
Prolonged Bleeding Time Incidence:
5.0-11.0%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
6.0-10.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
8.0-22.0%*
Severity: MILD
Onset: EARLY
Tired Incidence:
13.0%*
Severity: MILD
Onset: EARLY
Weakness Incidence:
13.0%*
Severity: MILD
Onset: DELAYED
Fever Incidence:
13.0-22.0%*
Severity: MILD
Onset: EARLY
Stomach Pain Incidence:
15.0-19.0%*
Severity: MILD
Onset: EARLY
Back Pain Incidence:
17.0-18.0%*
Severity: MILD
Onset: DELAYED
Infusion-related Reactions Incidence:
23.0-52.0%*
Severity: MODERATE
Onset: RAPID
Headache Incidence:
30.0-35.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Pregnancy & Lactation Information
FIRST Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

SECOND Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

THIRD Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


Learning More About
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