Xanax Xr Oral Tablet, Extended Release 0.5Mg Drug Medication Dosage Information
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Xanax XR: Oral tablet, extended release (0.5mg)

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Drug Image file DrugItem_5865.JPG
Xanax XR 0.5mg Tab
Pfizer US Pharmaceuticals
Pill Identification: X  |  0.5

What is this Medicine?

ALPRAZOLAM (al PRAY zoe lam) is a benzodiazepine. It is used to treat anxiety and panic attacks.

CVS Pharmacy Patient Statistics for Xanax XR: Oral tablet, extended release(0.5mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information

Xanax XR 0.5mg Extended-Release Tablet

NDC: 000090057
  • Prescription Required
  • Federally Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Panic Disorder

Storage Information
Store at 77 degrees F; excursions permitted to 59-86 degrees F
Xanax XR 0.5mg Extended-Release Tablet
Drug Image file DrugItem_5865.JPG
Pfizer US Pharmaceuticals
Pill Identification: X  |  0.5
Shape: pentagonal (5-sided)
Color: white

Reported Side Effects for Xanax XR 0.5mg Extended-Release Tablet

Weakness Incidence:
0.1-0.9%*
Severity: MILD
Onset: DELAYED
Light Sensitivity Incidence:
0.1-0.9%*
Severity: MODERATE
Onset: EARLY
Runny Nose Incidence:
0.1-0.9%*
Severity: MILD
Onset: EARLY
Ringing In Ears Incidence:
0.1-0.9%*
Severity: MILD
Onset: DELAYED
Fainting Incidence:
0.1-3.8%*
Severity: MILD
Onset: EARLY
Uncontrolled Urination Incidence:
0.1-0.9%*
Severity: MODERATE
Onset: EARLY
Hives Incidence:
0.1-0.9%*
Severity: MILD
Onset: RAPID
Convulsions Incidence:
0.1-0.9%*
Severity: SEVERE
Onset: DELAYED
Psychomotor Impairment Incidence:
0.1-0.9%*
Severity: MILD
Onset: EARLY
Loss Of Memory Incidence:
0.1-0.9%*
Severity: MODERATE
Onset: DELAYED
Hallucinations Incidence:
0.1-0.9%*
Severity: MODERATE
Onset: EARLY
Rapid Heart Rate Incidence:
0.1-15.4%*
Severity: MODERATE
Onset: RAPID
Elated Mood Incidence:
0.1-0.9%*
Severity: MODERATE
Onset: EARLY
Shortness Of Breath Incidence:
0.1-0.9%*
Severity: MODERATE
Onset: EARLY
Painful Urination Incidence:
0.1-0.9%*
Severity: MODERATE
Onset: EARLY
Swelling Incidence:
0.1-4.9%*
Severity: MODERATE
Onset: DELAYED
Nose Bleed Incidence:
0.1-0.9%*
Severity: MILD
Onset: DELAYED
Skin Rash Incidence:
0.1-0.9%*
Severity: MILD
Onset: EARLY
Fever Incidence:
0.1-0.9%*
Severity: MILD
Onset: EARLY
Hoarseness Incidence:
0.1-0.9%*
Severity: MODERATE
Onset: DELAYED
Extra Saliva Production Incidence:
0.1-5.6%*
Severity: MILD
Onset: EARLY
Low Blood Pressure Incidence:
0.1-4.7%*
Severity: MODERATE
Onset: RAPID
Low Muscle Tone Incidence:
0.1-0.9%*
Severity: MODERATE
Onset: DELAYED
Mania Incidence:
0.1-0.9%*
Severity: MODERATE
Onset: EARLY
Large Pupil Incidence:
0.1-0.9%*
Severity: MILD
Onset: EARLY
Feeling Sick Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Back Pain Incidence:
>1.0%*
Severity: MILD
Onset: DELAYED
Blurred Vision Incidence:
>1.0%*
Severity: MODERATE
Onset: EARLY
Chest Pain Incidence:
>1.0%*
Severity: MODERATE
Onset: EARLY
Diaphoresis Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Increased Sexual Desire Incidence:
1.0-7.7%*
Severity: MILD
Onset: DELAYED
Irritability Incidence:
>1.0%*
Severity: MILD
Onset: DELAYED
Overbreathing Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Distressed Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Weakness Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Rhinitis Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Headache Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Inability To Sleep Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Stuffy Nose Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Shaking Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Balance Problems Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Stomach Pain Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Rapid Heart Rate Incidence:
>1.0%*
Severity: MODERATE
Onset: EARLY
Muscle Cramps Incidence:
>1.0%*
Severity: MILD
Onset: DELAYED
Vomiting Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Nightmares Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Itching Incidence:
1.1%*
Severity: MILD
Onset: RAPID
Nervousness Incidence:
1.1-16.6%*
Severity: MILD
Onset: DELAYED
Muscle Pain Incidence:
1.5%*
Severity: MILD
Onset: EARLY
Confusion Incidence:
1.5-10.4%*
Severity: MODERATE
Onset: EARLY
Hot Flashes Incidence:
1.5%*
Severity: MODERATE
Onset: EARLY
Decreased Appetite Incidence:
1.5%*
Severity: MILD
Onset: DELAYED
Restlessness Incidence:
1.6-3.0%*
Severity: MODERATE
Onset: DELAYED
Dyskinesia Incidence:
1.7%*
Severity: MODERATE
Onset: DELAYED
Tiredness Incidence:
1.7%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
1.8-29.8%*
Severity: MILD
Onset: EARLY
Infection Incidence:
1.9-4.3%*
Severity: MILD
Onset: DELAYED
Weight Loss Incidence:
2.3-22.6%*
Severity: MILD
Onset: DELAYED
Joint Pain Incidence:
2.4%*
Severity: MILD
Onset: DELAYED
Paresthesias Incidence:
2.4%*
Severity: MILD
Onset: DELAYED
Flu Incidence:
2.4%*
Severity: MILD
Onset: DELAYED
Weight Gain Incidence:
2.7-27.2%*
Severity: MILD
Onset: DELAYED
Menstrual Cramps Incidence:
3.6%*
Severity: MILD
Onset: DELAYED
Decreased Memory Incidence:
5.5-33.1%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
6.0-22.0%*
Severity: MILD
Onset: EARLY
Decreased Sexual Desire Incidence:
6.0-14.4%*
Severity: MILD
Onset: DELAYED
Causing To Be Hungry Incidence:
7.0-32.7%*
Severity: MILD
Onset: DELAYED
Decreased Thinking Incidence:
7.2-28.8%*
Severity: MODERATE
Onset: EARLY
Incoordination Incidence:
7.2%*
Severity: MODERATE
Onset: DELAYED
Constipation Incidence:
8.1-26.2%*
Severity: MODERATE
Onset: DELAYED
Withdrawal Incidence:
10.0-35.0%*
Severity: MODERATE
Onset: EARLY
Dry Mouth Incidence:
10.2-14.7%*
Severity: MILD
Onset: EARLY
Irregular Periods Incidence:
10.4%*
Severity: MILD
Onset: DELAYED
Dysarthria Incidence:
10.9-23.3%*
Severity: MODERATE
Onset: DELAYED
Depression Incidence:
12.1-13.9%*
Severity: MODERATE
Onset: DELAYED
Tired Incidence:
13.9-48.6%*
Severity: MILD
Onset: EARLY
Drowsiness Incidence:
23.0-76.8%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Xanax XR 0.5mg Extended-Release Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Grapefruit juice and Xanax XR 0.5mg Extended-Release Tablet(Alprazolam)
Grapefruit juice and Alprazolam(Alprazolam)
Grapefruit juice and grapefruit-containing foods may increase the actions or side effects (such as drowsiness or slowed breathing) of Alprazolam. Avoid taking Alprazolam with grapefruit juice (or grapefruit) whenever possible, and do not increase your intake of grapefruit while taking Alprazolam. You may take Alprazolam with orange juice if desired. If you notice slurred speech, confusion, severe weakness, or difficulty breathing after taking Alprazolam, contact your health care provider immediately.
Major Lifestyle Interaction
Alcohol and Xanax XR 0.5mg Extended-Release Tablet(Alprazolam)
Alcohol and CNS Depressants(Alprazolam)
Avoid alcohol-containing drinks while taking this medicine. Using this drug along with alcohol can lead to serious side effects. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery until you know how this drug affects you, and especially if you are drinking alcohol-containing beverages. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.
Major Lifestyle Interaction
Marijuana and Xanax XR 0.5mg Extended-Release Tablet(Alprazolam)
Marijuana and Benzodiazepines(Alprazolam)
Avoid Marijuana, Medical while you are taking Benzodiazepines to reduce anxiety or to induce sleep or sedation. Using some of these drugs along with Marijuana can lead to serious side effects. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery if you are using Marijuana, Medical. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.
Moderate Lifestyle Interaction
Smoking and Xanax XR 0.5mg Extended-Release Tablet(Alprazolam)
Smoking and Alprazolam(Alprazolam)
Tobacco smoke may decrease the effectiveness of alprazolam in treating your condition. If you smoke tobacco, notify your prescriber if you notice that alprazolam is not working well for you. If you suddenly stop smoking tobacco, this may increase the actions of alprazolam; notify your prescriber if you notice increased drowsiness, dizziness, or other unusual side effects.
Minor Lifestyle Interaction
Caffeine-containing Foods/Beverages and Xanax XR 0.5mg Extended-Release Tablet(Alprazolam)
Caffeine-containing Foods/Beverages and Benzodiazepines(Alprazolam)
Although an interaction is possible, these drugs are often used together. Benzodiazepines include drugs for anxiety or sleep, such as Ativan, Dalmane, Doral, Halcion, Klonopin, Librium, ProSom, Restoril, Serax, Tranxene, Valium, and Xanax. Caffeine may increase nervousness or sleeplessness. If you are taking a Benzodiazepine to help you sleep, avoid taking Caffeine and Caffeine-containing foods or beverages like colas, coffee, teas, or chocolates within several hours prior to bedtime.
Pregnancy & Lactation Information
FIRST Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

SECOND Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

THIRD Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


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