Xiaflex Lyophilisate For Solution For Injection 0.9Mg Drug Medication Dosage Information
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Xiaflex: Lyophilisate for solution for injection (0.9mg)

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What is this Medicine?

COLLAGENASE (kohl LAH jen ace) is used to treat Dupuytren's contracture. This medicine may help straighten a bent finger by breaking up hard tissue. It is also used for Peyronie's disease by breaking up the hard tissue plaque that causes the curvature in the penis.

In-Depth Information

Xiaflex 0.9mg Powder for Injection

NDC: 668870003
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Dupuytren's Contracture, Peyronie's Disease

Storage Information
Store unreconstituted product in refrigerator (36 to 46 degrees F)
Do not freeze
Discard unused portion. Do not store for later use.
Xiaflex 0.9mg Powder for Injection

Reported Side Effects for Xiaflex 0.9mg Powder for Injection

Tendon Rupture Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Corporal Rupture Incidence:
0.5%*
Severity: SEVERE
Onset: DELAYED
Painful Intercourse Incidence:
1.1%*
Severity: MODERATE
Onset: DELAYED
Irritation Of The Penis Incidence:
1.1%*
Severity: MODERATE
Onset: RAPID
Pelvic Pain Incidence:
1.1%*
Severity: MILD
Onset: DELAYED
Skin Discoloration Incidence:
1.8%*
Severity: MILD
Onset: DELAYED
Impotence (erectile Dysfunction) Incidence:
1.8%*
Severity: MODERATE
Onset: DELAYED
Bruise Incidence:
3.7-65.5%*
Severity: MODERATE
Onset: EARLY
Itching Incidence:
4.0-15.0%*
Severity: MILD
Onset: RAPID
Skin Redness Incidence:
6.0%*
Severity: MODERATE
Onset: EARLY
Skin Laceration Incidence:
9.0-22.0%*
Severity: MODERATE
Onset: DELAYED
Enlarged Lymph Nodes Incidence:
13.0%*
Severity: MODERATE
Onset: DELAYED
Bruise Incidence:
14.5-70.0%*
Severity: MILD
Onset: DELAYED
Bleeding Incidence:
38.0%*
Severity: MODERATE
Onset: EARLY
Painful Penis Incidence:
45.4%*
Severity: MODERATE
Onset: RAPID
Penile Edema Incidence:
55.0%*
Severity: SEVERE
Onset: EARLY
Swelling Incidence:
55.0-73.0%*
Severity: MODERATE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Pregnancy & Lactation Information
FIRST Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

SECOND Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

THIRD Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Lactation

Compatible - This drug is generally safe to take by nursing mothers.


Learning More About
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