Zestoretic Oral Tablet 10-12.5Mg Drug Medication Dosage Information
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Zestoretic: Oral tablet (10-12.5mg)

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Drug Image file DrugItem_5731.JPG
Zestoretic 10mg-12.5mg Tab
AstraZeneca Pharmaceuticals LP
Pill Identification: ZESTORETIC  |  141
Drug Image file DrugItem_5731.JPG
Zestoretic 10mg-12.5mg Tab
AstraZeneca Pharmaceuticals LP
Pill Identification: ZESTORETIC  |  141

What is this Medicine?

HYDROCHLOROTHIAZIDE; LISINOPRIL (hye droe klor oh THYE a zide; lyse IN oh pril) is a combination of a diuretic and an ACE inhibitor. It is used to treat high blood pressure.

CVS Pharmacy Patient Statistics for Zestoretic: Oral tablet(10-12.5mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
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Zestoretic 10mg-12.5mg Tablet

NDC: 003100141
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Hypertension

Storage Information
Protect from light
Store at controlled room temperature (between 68 and 77 degrees F)
Avoid excessive humidity
Zestoretic 10mg-12.5mg Tablet
Drug Image file DrugItem_5731.JPG
AstraZeneca Pharmaceuticals LP
Pill Identification: ZESTORETIC  |  141
Shape: round
Color: peach
Drug Image file DrugItem_19352.JPG
AstraZeneca Pharmaceuticals LP
Pill Identification: ZESTORETIC  |  141
Shape: round
Color: peach

Reported Side Effects for Zestoretic 10mg-12.5mg Tablet

Shortness Of Breath Incidence:
0.3-1.0%*
Severity: MODERATE
Onset: EARLY
Drowsiness Incidence:
0.3-1.0%*
Severity: MILD
Onset: EARLY
Ear Pain Incidence:
0.3-1.0%*
Severity: MILD
Onset: EARLY
Flushing Incidence:
0.3-1.0%*
Severity: MILD
Onset: RAPID
Rapid Heart Rate Incidence:
0.3-1.0%*
Severity: MODERATE
Onset: EARLY
Muscle And/Or Bone Pain Incidence:
0.3-1.0%*
Severity: MILD
Onset: EARLY
Rhinitis Incidence:
0.3-1.0%*
Severity: MILD
Onset: EARLY
Depression Incidence:
0.3-1.0%*
Severity: MODERATE
Onset: DELAYED
Constipation Incidence:
0.3-1.0%*
Severity: MODERATE
Onset: DELAYED
Decreased Sexual Desire Incidence:
0.3-1.0%*
Severity: MILD
Onset: DELAYED
Dry Mouth Incidence:
0.3-1.0%*
Severity: MILD
Onset: EARLY
Stomach Pain Incidence:
0.3-1.0%*
Severity: MILD
Onset: EARLY
Infection Incidence:
0.3-1.0%*
Severity: MILD
Onset: DELAYED
Flu Incidence:
0.3-1.0%*
Severity: MILD
Onset: DELAYED
Stuffy Nose Incidence:
0.3-1.0%*
Severity: MILD
Onset: EARLY
Muscle Pain Incidence:
0.3-1.0%*
Severity: MILD
Onset: EARLY
Balance Problems Incidence:
0.3-1.0%*
Severity: MILD
Onset: EARLY
Sore Throat Incidence:
0.3-1.0%*
Severity: MILD
Onset: DELAYED
Anaphylactoid Reactions Incidence:
0.3-1.0%*
Severity: SEVERE
Onset: RAPID
Ringing In Ears Incidence:
0.3-1.0%*
Severity: MILD
Onset: DELAYED
Heartburn Incidence:
0.3-1.0%*
Severity: MILD
Onset: EARLY
Fever Incidence:
0.3-1.0%*
Severity: MILD
Onset: EARLY
Sinus Infection Incidence:
0.3-1.0%*
Severity: MILD
Onset: DELAYED
Diaphoresis Incidence:
0.3-1.0%*
Severity: MILD
Onset: EARLY
Itching Incidence:
0.3-1.0%*
Severity: MILD
Onset: RAPID
Chest Pain Incidence:
0.3-1.0%*
Severity: MODERATE
Onset: EARLY
Blurred Vision Incidence:
0.3-1.0%*
Severity: MODERATE
Onset: EARLY
Back Pain Incidence:
0.3-1.0%*
Severity: MILD
Onset: DELAYED
Postural Low Blood Pressure Incidence:
0.5%*
Severity: MODERATE
Onset: DELAYED
Fainting Incidence:
0.8%*
Severity: MILD
Onset: EARLY
Skin Rash Incidence:
1.2%*
Severity: MILD
Onset: EARLY
Impotence (erectile Dysfunction) Incidence:
1.2%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
1.3%*
Severity: MILD
Onset: EARLY
Low Blood Pressure Incidence:
1.4%*
Severity: MODERATE
Onset: RAPID
Vomiting Incidence:
1.4%*
Severity: MILD
Onset: EARLY
High Potassium Level Incidence:
1.4%*
Severity: SEVERE
Onset: DELAYED
Paresthesias Incidence:
1.5%*
Severity: MILD
Onset: DELAYED
Weakness Incidence:
1.8%*
Severity: MILD
Onset: DELAYED
Muscle Cramps Incidence:
2.0%*
Severity: MILD
Onset: DELAYED
Upset Stomach Incidence:
2.2%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
2.5%*
Severity: MILD
Onset: EARLY
Tired Incidence:
3.7%*
Severity: MILD
Onset: EARLY
Cough Incidence:
3.9%*
Severity: MILD
Onset: DELAYED
Headache Incidence:
5.2%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
7.5%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Zestoretic 10mg-12.5mg Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Moderate Lifestyle Interaction
Alcohol and Zestoretic 10mg-12.5mg Tablet(Hydrochlorothiazide)
Alcohol and Antihypertensives(Hydrochlorothiazide)
Although an interaction is possible, Ethanol (alchohol) and Antihypertensive Agents (drugs used to reduce high blood pressure) may be used together. Ethanol or alchohol-containing beverages may increase the effects of Antihypertensive Agents on your blood pressure. If the blood pressure drops too low while taking Ethanol and Antihypertensive Agents, you may become dizzy or feel faint. To limit this interaction, avoid alcohol-containing beverages while taking medicines to lower your blood pressure. Do not stand or sit up too quickly. Contact your prescriber if you have dizziness which does not go away.
Pregnancy & Lactation Information
FIRST Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

SECOND Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

THIRD Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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