Zoladex Implant 10.8Mg Drug Medication Dosage Information
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Zoladex: Implant (10.8mg)

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What is this Medicine?

GOSERELIN (GOE se rel in) is similar to a hormone found in the body. It lowers the amount of sex hormones that the body makes. Men will have lower testosterone levels and women will have lower estrogen levels while taking this medicine. In men, this medicine is used to treat prostate cancer; the injection is either given once per month or once every 12 weeks. A once per month injection (only) is used to treat women with endometriosis, dysfunctional uterine bleeding, or advanced breast cancer.

In-Depth Information
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Zoladex 10.8mg 3-Month Implant

NDC: 003100961
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Breast Cancer, Dysfunctional Uterine Bleeding, Prostate Cancer, Endometriosis

Sometimes used for but not FDA approved for the following conditions:
Uterine Leiomyomata, Benign Prostatic Hyperplasia (BPH)

Storage Information
Store below 77 degrees F
Zoladex 10.8mg 3-Month Implant

Reported Side Effects for Zoladex 10.8mg 3-Month Implant

Chest Pain Incidence:
<5.0%*
Severity: MODERATE
Onset: EARLY
Back Pain Incidence:
<7.0%*
Severity: MILD
Onset: DELAYED
Vomiting Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Brain Attack Incidence:
<5.0%*
Severity: SEVERE
Onset: EARLY
Heart Attack Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Flu Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Infection Incidence:
<13.0%*
Severity: MILD
Onset: DELAYED
Increased Blood Sugar Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Blood In The Urine Incidence:
<7.0%*
Severity: MODERATE
Onset: DELAYED
Stomach Pain Incidence:
<11.0%*
Severity: MILD
Onset: EARLY
Retaining Urine Incidence:
<5.0%*
Severity: MODERATE
Onset: EARLY
Uncontrolled Urination Incidence:
<5.0%*
Severity: MODERATE
Onset: EARLY
Sinus Infection Incidence:
<3.0%*
Severity: MILD
Onset: DELAYED
Weight Gain Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Paresthesias Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Feeling Sick Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Injection Site Reaction Incidence:
<6.0%*
Severity: MILD
Onset: RAPID
Increased Urination Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Impotence (erectile Dysfunction) Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Vomiting Of Blood Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Elevated Hepatic Enzymes Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Lightheadedness Incidence:
<6.0%*
Severity: MILD
Onset: EARLY
Chills Incidence:
<5.0%*
Severity: MILD
Onset: RAPID
Depression Incidence:
<54.0%*
Severity: MODERATE
Onset: DELAYED
Diabetes Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Loose Stools Incidence:
<40.0%*
Severity: MILD
Onset: EARLY
Cough Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Shortness Of Breath Incidence:
<5.0%*
Severity: MODERATE
Onset: EARLY
Constipation Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Nervousness Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Fever Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Gout Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Headache Incidence:
<75.0%*
Severity: MILD
Onset: EARLY
Heart Failure Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Chest Pain Incidence:
<5.0%*
Severity: MODERATE
Onset: EARLY
High Blood Pressure Incidence:
<6.0%*
Severity: MODERATE
Onset: EARLY
Anemia Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Blood Clot In Lung Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Itching Incidence:
<5.0%*
Severity: MILD
Onset: RAPID
Breast Pain Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Migraine Incidence:
<7.0%*
Severity: MODERATE
Onset: EARLY
Excessive Mucle Tone Incidence:
>1.0%*
Severity: MODERATE
Onset: DELAYED
Drowsiness Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Hair Loss Incidence:
>1.0%*
Severity: MILD
Onset: DELAYED
Upset Stomach Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Bruise Incidence:
>1.0%*
Severity: MILD
Onset: DELAYED
Vaginal Infection Incidence:
1.0-75.0%*
Severity: MODERATE
Onset: DELAYED
Dry Eyes Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Joint Pain Incidence:
>1.0%*
Severity: MILD
Onset: DELAYED
Nose Bleed Incidence:
>1.0%*
Severity: MILD
Onset: DELAYED
Dry Skin Incidence:
>1.0%*
Severity: MILD
Onset: DELAYED
Rhinitis Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Dry Mouth Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Gas Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Bleeding Incidence:
>1.0%*
Severity: MODERATE
Onset: EARLY
Skin Discoloration Incidence:
>1.0%*
Severity: MILD
Onset: DELAYED
Vaginal Bleeding Incidence:
>1.0%*
Severity: MODERATE
Onset: DELAYED
Lazy Eye Incidence:
>1.0%*
Severity: MODERATE
Onset: DELAYED
Causing To Be Hungry Incidence:
2.0%*
Severity: MILD
Onset: DELAYED
Muscle Cramps Incidence:
2.0%*
Severity: MILD
Onset: DELAYED
Muscle Pain Incidence:
3.0%*
Severity: MILD
Onset: EARLY
Heavy Menstrual Period Incidence:
4.0%*
Severity: MILD
Onset: DELAYED
Decreased Appetite Incidence:
5.0%*
Severity: MILD
Onset: DELAYED
Upset Stomach Incidence:
5.0-11.0%*
Severity: MILD
Onset: EARLY
Tiredness Incidence:
5.0-8.0%*
Severity: MILD
Onset: EARLY
Sore Throat Incidence:
5.0-6.0%*
Severity: MILD
Onset: DELAYED
Inability To Sleep Incidence:
5.0-11.0%*
Severity: MILD
Onset: EARLY
Swelling Incidence:
5.0-7.0%*
Severity: MODERATE
Onset: DELAYED
Tired Incidence:
5.0%*
Severity: MILD
Onset: EARLY
Weakness Incidence:
5.0-11.0%*
Severity: MILD
Onset: DELAYED
Bone Pain Incidence:
6.0%*
Severity: MODERATE
Onset: DELAYED
Diaphoresis Incidence:
6.0-45.0%*
Severity: MILD
Onset: EARLY
Pelvic Pain Incidence:
6.0-9.0%*
Severity: MILD
Onset: DELAYED
Skin Rash Incidence:
6.0-8.0%*
Severity: MILD
Onset: EARLY
Menstrual Cramps Incidence:
7.0%*
Severity: MILD
Onset: DELAYED
Hirsutism Incidence:
7.0%*
Severity: MILD
Onset: DELAYED
Rectal Infection Incidence:
8.0%*
Severity: MODERATE
Onset: DELAYED
Increased Sexual Desire Incidence:
12.0%*
Severity: MILD
Onset: DELAYED
Bladder Infection Incidence:
16.0%*
Severity: MODERATE
Onset: DELAYED
Increase In Breast Size Incidence:
18.0%*
Severity: MILD
Onset: DELAYED
Fluid Retention Incidence:
21.0%*
Severity: MODERATE
Onset: DELAYED
Dandruff Incidence:
26.0%*
Severity: MILD
Onset: DELAYED
Acne Incidence:
42.0%*
Severity: MILD
Onset: DELAYED
Hot Flashes Incidence:
46.0-96.0%*
Severity: MODERATE
Onset: EARLY
Decreased Sexual Desire Incidence:
47.7-61.0%*
Severity: MILD
Onset: DELAYED
Peripheral Vasodilation Incidence:
57.0%*
Severity: MODERATE
Onset: RAPID
Emotional Lability Incidence:
60.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Pregnancy & Lactation Information
FIRST Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

SECOND Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

THIRD Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


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