Zoloft Oral Tablet 100Mg Drug Medication Dosage Information
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Zoloft: Oral tablet (100mg)

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Drug Image file DrugItem_7254.JPG
Zoloft 100mg Tab
Pfizer US Pharmaceuticals
Pill Identification: ZOLOFT  |  100mg

What is this Medicine?

SERTRALINE (SER tra leen) is used to treat depression. It may also be used to treat obsessive compulsive disorder, panic disorder, post-trauma stress, premenstrual dysphoric disorder (PMDD) or social anxiety.

CVS Pharmacy Patient Statistics for Zoloft: Oral tablet(100mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
Select a Medication

Zoloft 100mg Tablet

NDC: 000494910
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Premenstrual Dysphoric Disorder (PMDD), Posttraumatic Stress Disorder (PTSD), Social Phobia (social Anxiety Disorder), Obsessive-compulsive Disorder (OCD), Panic Disorder, Depression

Sometimes used for but not FDA approved for the following conditions:
Pruritus, Menopause, Separation Anxiety Disorder, Hot Flashes, Premature Ejaculation, Generalized Anxiety Disorder (GAD)

Storage Information
Store at 77 degrees F; excursions permitted to 59-86 degrees F
Zoloft 100mg Tablet
Drug Image file DrugItem_7254.JPG
Pfizer US Pharmaceuticals
Pill Identification: ZOLOFT  |  100mg
Shape: oblong
Color: yellow

Reported Side Effects for Zoloft 100mg Tablet

Hyperacusis Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Blood In The Urine Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Stomach Pain Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Ambras Syndrome Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Dry Eyes Incidence:
<0.1%*
Severity: MILD
Onset: EARLY
Overbreathing Incidence:
<0.1%*
Severity: MILD
Onset: EARLY
Vaginal Infection Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Decreased Reflexes Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Low Muscle Tone Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Shallow, Slow Breathing Incidence:
<0.1%*
Severity: MODERATE
Onset: RAPID
Secretion Of Tears Incidence:
<0.1%*
Severity: MILD
Onset: EARLY
Mouth Ulcers Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Inflamed Vocal Cords Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Hoarseness Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Dyskinesia Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Double Vision Incidence:
<0.1%*
Severity: MILD
Onset: EARLY
Choreoathetosis Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Bulging Eyes Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Blistery Rash Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Fecal Incontinence Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Increase In Breast Size Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Back Pain Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Gingival Hyperplasia Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Inflamed Tongue Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Decreased Breathing Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Anaphylactoid Reactions Incidence:
<0.1%*
Severity: SEVERE
Onset: RAPID
Gynecomastia Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Coughing Up Blood Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Thoughts Of Suicide Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Hiccups Incidence:
<0.1%*
Severity: MILD
Onset: EARLY
Heart Attack Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Pale Skin Incidence:
<0.1%*
Severity: MILD
Onset: EARLY
Stomach Ulcer Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Priapism Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Drooping Eyelids Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Scotomata Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Bladder Infection Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Allergic Skin Reaction Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Skin Discoloration Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Coma Incidence:
<0.1%*
Severity: SEVERE
Onset: EARLY
Inflamed Colon Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Scaly And Itchy Rashes Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Sleep-Walking Incidence:
<0.1%*
Severity: MILD
Onset: EARLY
Tenesmus Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Angioedema Incidence:
<0.1%*
Severity: SEVERE
Onset: RAPID
Anemia Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Rectal Infection Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Light Sensitivity Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Decreased Urination Incidence:
<0.1%*
Severity: SEVERE
Onset: EARLY
Melena Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
High Eye Blood Pressure Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Heavy Menstrual Period Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Breast Pain Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Bleeding Within The Eye Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Low Blood Sugar Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Inflamed Stomach Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Mouth Sores Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Teeth Grinding Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Vaginal Discharge Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Ear Pain Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Emotional Lability Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Belching Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Elated Mood Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Paranoia Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Rash With Pustules Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Photosensitivity Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Excessive Thirst Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Hyperesthesia Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Flushing Incidence:
0.1-1.0%*
Severity: MILD
Onset: RAPID
Muscle Weakness Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Large Pupil Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Nightmares Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Nighttime Urination Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Rapid Heart Rate Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: RAPID
Hallucinations Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Balance Problems Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Hives Incidence:
0.1-1.0%*
Severity: MILD
Onset: RAPID
Retaining Urine Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Uncontrolled Urination Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Sinus Infection Incidence:
0.1-2.0%*
Severity: MILD
Onset: DELAYED
Itching Incidence:
0.1-1.0%*
Severity: MILD
Onset: RAPID
Postural Low Blood Pressure Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Eye Pain Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Fast Eye Movements Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Migraine Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Low Blood Pressure Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: RAPID
High Blood Pressure Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Fever Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Throat Inflammation Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Nose Bleed Incidence:
>0.1%*
Severity: MILD
Onset: DELAYED
Swelling Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Painful Urination Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Shortness Of Breath Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Menstrual Cramps Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Depression Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Cough Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Joint Pain Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
No Menstrual Periods Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Hair Loss Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Acne Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Dystonic Reaction Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Tooth Cavities Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Conjunctivitis Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Confusion Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Breathing Difficulties Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: RAPID
Blurred Vision Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Incoordination Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Loss Of Memory Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Vaginal Bleeding Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Fainting Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Dry Skin Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Difficulty Swallowing Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Muscle Cramps Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Fluid Retention Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Inceased Urination Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Convulsions Incidence:
0.2%*
Severity: SEVERE
Onset: DELAYED
Mania Incidence:
0.4%*
Severity: MODERATE
Onset: EARLY
Elevated Hepatic Enzymes Incidence:
0.8%*
Severity: MODERATE
Onset: DELAYED
Yawning Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Excessive Mucle Tone Incidence:
>1.0%*
Severity: MODERATE
Onset: DELAYED
Hypoesthesia Incidence:
>1.0%*
Severity: MILD
Onset: DELAYED
Rhinitis Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Hyperkinesis Incidence:
>1.0%*
Severity: MILD
Onset: DELAYED
Chest Pain Incidence:
>1.0%*
Severity: MODERATE
Onset: EARLY
Back Pain Incidence:
>1.0%*
Severity: MILD
Onset: DELAYED
Impotence (erectile Dysfunction) Incidence:
>1.0%*
Severity: MODERATE
Onset: DELAYED
Feeling Sick Incidence:
1.0%*
Severity: MILD
Onset: EARLY
Ringing In Ears Incidence:
>1.0%*
Severity: MILD
Onset: DELAYED
Muscle Pain Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Causing To Be Hungry Incidence:
>1.0%*
Severity: MILD
Onset: DELAYED
Rapid Heart Rate Incidence:
>1.0%*
Severity: MODERATE
Onset: EARLY
Weakness Incidence:
>1.0%*
Severity: MILD
Onset: DELAYED
Orgasm Dysfunction Incidence:
2.0%*
Severity: MILD
Onset: DELAYED
Paresthesias Incidence:
2.0%*
Severity: MILD
Onset: DELAYED
Bruises Incidence:
>2.0%*
Severity: MILD
Onset: DELAYED
Visual Impairment Incidence:
3.0%*
Severity: SEVERE
Onset: EARLY
Skin Rash Incidence:
3.0%*
Severity: MILD
Onset: EARLY
Nervousness Incidence:
4.0%*
Severity: MILD
Onset: DELAYED
Vomiting Incidence:
4.0%*
Severity: MILD
Onset: EARLY
Distressed Incidence:
5.0%*
Severity: MILD
Onset: EARLY
Constipation Incidence:
6.0%*
Severity: MODERATE
Onset: DELAYED
Decreased Sexual Desire Incidence:
6.0%*
Severity: MILD
Onset: DELAYED
Decreased Appetite Incidence:
6.0%*
Severity: MILD
Onset: DELAYED
Excessive Sweating Incidence:
7.0%*
Severity: MILD
Onset: DELAYED
Shaking Incidence:
8.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
8.0%*
Severity: MILD
Onset: EARLY
Tired Incidence:
12.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
12.0%*
Severity: MILD
Onset: EARLY
Drowsiness Incidence:
13.0%*
Severity: MILD
Onset: EARLY
Ejaculation Dysfunction Incidence:
>14.0%*
Severity: MODERATE
Onset: DELAYED
Loose Stools Incidence:
20.0%*
Severity: MILD
Onset: EARLY
Inability To Sleep Incidence:
21.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
25.0%*
Severity: MILD
Onset: EARLY
Headache Incidence:
25.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Zoloft 100mg Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Moderate Lifestyle Interaction
Grapefruit juice and Zoloft 100mg Tablet(Sertraline Hydrochloride)
Grapefruit juice and Sertraline Hydrochloride(Sertraline Hydrochloride)
In theory, grapefruit juice and grapefruits might increase the appearance of side effects of Sertraline (Zoloft), but it is not clear if this interaction is significant. If possible, avoid ingesting grapefruit juice while taking Sertraline. At the very least, do not significantly change your daily intake of grapefruit and grapefruit juice. Also, the Sertraline Oral Concentrate Solution should not be mixed in grapefruit juice; this solution is only mixable with water, ginger-ale, lemonade, orange juice or lemon-lime soda; do not mix in any other liquids.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


Learning More About
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