Esmolol Hydrochloride: Solution for injection (10mg)

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What is this Medicine?

ESMOLOL is a beta-blocker. Beta-blockers reduce the workload on the heart and help it to beat more regularly. This medicine is used to slow down a fast heart rate and reduce high blood pressure.

Similar Brand Name Drugs : Brevibloc: Solution for injection (10mg) | Brevibloc: Solution for injection (20mg)

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Esmolol Hydrochloride 100mg/10ml Solution for Injection

NDC: 553900062

Prescription Required
Not a Controlled Drug
(CSA Schedule)
FDA Approved

FDA approved for the following conditions:
Atrial Flutter, Paroxysmal Supraventricular Tachycardia (PSVT), Atrial Fibrillation, Perioperative Hypertension, Postoperative Hypertension

Sometimes used for but not FDA approved for the following conditions:
Acute Myocardial Infarction, Hypertensive Emergency, Hypertensive Urgency, Unstable Angina

Storage Information
Protect from freezing
Store at 77 degrees F; excursions permitted to 59-86 degrees F
Avoid excessive heat (above 104 degrees F)

Esmolol Hydrochloride 100mg/10ml Solution for Injection

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Reported Side Effects for Esmolol Hydrochloride 100mg/10ml Solution for Injection

Flushing Incidence: <1.0%* Severity: MILD
Onset: RAPID

Pale Skin Incidence: <1.0%* Severity: MILD
Onset: EARLY

Paresthesias Incidence: <1.0%* Severity: MILD
Onset: DELAYED

Chest Pain Incidence: <1.0%* Severity: MODERATE
Onset: EARLY

Breathing Difficulties Incidence: <1.0%* Severity: SEVERE
Onset: RAPID

Weakness Incidence: <1.0%* Severity: MILD
Onset: DELAYED

Fainting Incidence: <1.0%* Severity: MILD
Onset: EARLY

Convulsions Incidence: <1.0%* Severity: SEVERE
Onset: DELAYED

Stomach Pain Incidence: <1.0%* Severity: MILD
Onset: EARLY

Dry Mouth Incidence: <1.0%* Severity: MILD
Onset: EARLY

Fluid In Lungs Incidence: <1.0%* Severity: SEVERE
Onset: EARLY

Stuffy Nose Incidence: <1.0%* Severity: MILD
Onset: EARLY

Irritated Blood Vessels Incidence: <1.0%* Severity: MODERATE
Onset: RAPID

Skin Necrosis Incidence: <1.0%* Severity: SEVERE
Onset: EARLY

Fever Incidence: <1.0%* Severity: MILD
Onset: EARLY

Shortness Of Breath Incidence: <1.0%* Severity: MODERATE
Onset: EARLY

Upset Stomach Incidence: <1.0%* Severity: MILD
Onset: EARLY

Tissue Death Incidence: <1.0%* Severity: SEVERE
Onset: EARLY

Depression Incidence: <1.0%* Severity: MODERATE
Onset: DELAYED

Constipation Incidence: <1.0%* Severity: MODERATE
Onset: DELAYED

Slow Heart Beat Incidence: <1.0%* Severity: SEVERE
Onset: RAPID

Heart Block Incidence: <1.0%* Severity: SEVERE
Onset: EARLY

Nervousness Incidence: <1.0%* Severity: MILD
Onset: DELAYED

Decreased Appetite Incidence: <1.0%* Severity: MILD
Onset: DELAYED

Wheezing Incidence: <1.0%* Severity: MODERATE
Onset: RAPID

Tired Incidence: 1.0%* Severity: MILD
Onset: EARLY

Vomiting Incidence: 1.0%* Severity: MILD
Onset: EARLY

Confusion Incidence: 2.0%* Severity: MODERATE
Onset: EARLY

Headache Incidence: 2.0%* Severity: MILD
Onset: EARLY

Distressed Incidence: 2.0%* Severity: MILD
Onset: EARLY

Lightheadedness Incidence: 3.0%* Severity: MILD
Onset: EARLY

Drowsiness Incidence: 3.0%* Severity: MILD
Onset: EARLY

Upset Stomach Incidence: 7.0%* Severity: MILD
Onset: EARLY

Injection Site Reaction Incidence: 8.0%* Severity: MILD
Onset: RAPID

Diaphoresis Incidence: 10.0%* Severity: MILD
Onset: EARLY

Low Blood Pressure Incidence: 20.0-50.0%* Severity: MODERATE
Onset: RAPID

*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.

Daily Life Interactions for Esmolol Hydrochloride 100mg/10ml Solution for Injection

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

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Major Lifestyle Interaction

Marijuana and Esmolol Hydrochloride 100mg/10ml Solution for Injection(Esmolol Hydrochloride)

Marijuana and Beta-blockers(Esmolol Hydrochloride)

Do not take Marijuana, Medical and Beta-Blockers (examples: Coreg, Metoprolol or Lopressor or Toprol, Nadolol or Corgard, Propranolol or Inderal) together without talking to your health care provider. Marijuana, Medical may decrease the effectiveness of Beta-Blockers. It is possible that Marijuana, Medical can cause high blood pressure, increased heart rate or other heart-related side effects in persons predisposed to these conditions, which may make the Beta-Blocker-type drug less effective at treating heart or blood pressure related problems.

Moderate Lifestyle Interaction

Alcohol and Esmolol Hydrochloride 100mg/10ml Solution for Injection(Esmolol Hydrochloride)

Alcohol and Antihypertensives(Esmolol Hydrochloride)

Although an interaction is possible, Ethanol (alchohol) and Antihypertensive Agents (drugs used to reduce high blood pressure) may be used together. Ethanol or alchohol-containing beverages may increase the effects of Antihypertensive Agents on your blood pressure. If the blood pressure drops too low while taking Ethanol and Antihypertensive Agents, you may become dizzy or feel faint. To limit this interaction, avoid alcohol-containing beverages while taking medicines to lower your blood pressure. Do not stand or sit up too quickly. Contact your prescriber if you have dizziness which does not go away.

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Pregnancy & Lactation Information

FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

THIRD Trimester