Etodolac: Oral tablet, extended release (400mg)
Detailed Information
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What is this Medicine?
ETODOLAC (ee toe DOE lak) is a non-steroidal anti-inflammatory drug (NSAID). It is used to reduce swelling and to treat pain. This medicine may be used to treat osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
CVS Pharmacy Patient Statistics for Etodolac: Oral tablet, extended release(400mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
Select a Medication
Etodolac 400mg Extended-Release Tablet
NDC: 000931122-
Prescription Required
-
Not a Controlled Drug
(CSA Schedule) -
FDA Approved
FDA approved for the following conditions:
Juvenile Rheumatoid Arthritis (JRA)/juvenile Idiopathic Arthritis (JIA), Rheumatoid Arthritis, Osteoarthritis
Juvenile Rheumatoid Arthritis (JRA)/juvenile Idiopathic Arthritis (JIA), Rheumatoid Arthritis, Osteoarthritis
Storage Information
Store at controlled room temperature (between 68 and 77 degrees F)
Avoid excessive humidity
Avoid excessive heat (above 104 degrees F)
Store at controlled room temperature (between 68 and 77 degrees F)
Avoid excessive humidity
Avoid excessive heat (above 104 degrees F)
Reported Side Effects for Etodolac 400mg Extended-Release Tablet
Flushing
Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Onset: RAPID
Belching
Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
Eosinophilia
Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Elevated Hepatic Enzymes
Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Bruise
Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Onset: DELAYED
Metallic Taste
Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
Diaphoresis
Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
Conjunctivitis
Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Confusion
Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Onset: EARLY
Blistery Rash
Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Onset: EARLY
Breathing Difficulties
Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Onset: RAPID
Low Kidney Function
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Inflamed Brain
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Abnormal Heart Rhythm
Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Onset: EARLY
Anaphylactoid Reactions
Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Onset: RAPID
Inflamed Blood Vessels
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Fainting
Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
Brain Attack
Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Onset: EARLY
Inceased Urination
Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
Inflamed Pancreas
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Heart Attack
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Low White Blood Cell Counts
Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Yellow Skin
Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Infection
Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Onset: DELAYED
Increased Blood Sugar
Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Liver Infection
Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Weight Loss
Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Onset: DELAYED
Weight Gain
Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Onset: DELAYED
Visual Impairment
Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Onset: EARLY
Vesicular Rash
Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Onset: DELAYED
Lyell'S Syndrome
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Darkened Skin Patches
Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Onset: DELAYED
Rhinitis
Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
Kidney Damage
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Kidney Failure
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Bruises
Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Onset: DELAYED
Photosensitivity
Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Onset: DELAYED
Stomach Ulcer
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Paresthesias
Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Onset: DELAYED
Pancytopenia
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Rapid Heart Rate
Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Onset: EARLY
Rash With Pustules
Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
Vaginal Discharge
Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Onset: DELAYED
Irritability
Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Onset: DELAYED
Kidney Inflammation
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Death Of Liver Tissue
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Liver Failure
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Deafness
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Low White Blood Cells
Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Kidney Stones
Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Muscle Pain
Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
Inability To Sleep
Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
High Blood Pressure
Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Onset: EARLY
Hemolytic Anemia
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Heart Failure
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Exfoliative Dermatitis
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Throat Inflammation
Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Erythema Multiforme
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Shortness Of Breath
Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Onset: EARLY
Bladder Infection
Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Inflamed Colon
Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Aplastic Anemia
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Decreased Appetite
Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Onset: DELAYED
Angioedema
Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Onset: RAPID
Anemia
Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Severe Allergy
Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Onset: RAPID
Hair Loss
Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Onset: DELAYED
Hives
Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Onset: RAPID
Dry Mouth
Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
No White Blood Cells
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Cholestasis
Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Low Platelet Count
Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Mouth Ulcers
Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Stevens-Johnson Syndrome
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Sinus Infection
Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Onset: DELAYED
Throat Tightening
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Intestinal Bleeding
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Hole In Intestines
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Protein In The Urine
Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Onset: DELAYED
Light Sensitivity
Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Onset: EARLY
Sore Throat
Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Onset: DELAYED
Blood In The Urine
Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Decreased Urination
Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Onset: EARLY
Joint Pain
Incidence:
1.0-3.0%*
Severity: MILD
Onset: DELAYED
Onset: DELAYED
Skin Rash
Incidence:
1.0-3.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
Constipation
Incidence:
1.0-3.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Depression
Incidence:
1.0-3.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Painful Urination
Incidence:
1.0-3.0%*
Severity: MODERATE
Onset: EARLY
Onset: EARLY
Melena
Incidence:
1.0-3.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Itching
Incidence:
1.0-3.0%*
Severity: MILD
Onset: RAPID
Onset: RAPID
Ringing In Ears
Incidence:
1.0-3.0%*
Severity: MILD
Onset: DELAYED
Onset: DELAYED
Vomiting
Incidence:
1.0-3.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
Tired
Incidence:
1.0-3.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
Heartburn
Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
Blurred Vision
Incidence:
1.0-3.0%*
Severity: MODERATE
Onset: EARLY
Onset: EARLY
Inflamed Stomach
Incidence:
1.0-3.0%*
Severity: MODERATE
Onset: DELAYED
Onset: DELAYED
Increased Urination
Incidence:
1.0-3.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
Upset Stomach
Incidence:
3.0-9.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
Lightheadedness
Incidence:
3.0-9.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
Weakness
Incidence:
3.0-9.0%*
Severity: MILD
Onset: DELAYED
Onset: DELAYED
Gas
Incidence:
3.0-9.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
Stomach Pain
Incidence:
3.0-9.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
Feeling Sick
Incidence:
3.0-9.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
Loose Stools
Incidence:
3.0-9.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
Upset Stomach
Incidence:
10.0%*
Severity: MILD
Onset: EARLY
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Etodolac 400mg Extended-Release Tablet
Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.
Major Lifestyle Interaction
Alcohol and Etodolac 400mg Extended-Release Tablet(Etodolac)
Alcohol and Nonsteroidal antiinflammatory drugs (systemic)(Etodolac)
Side effects from this drug may get worse if you drink alcohol-containing drinks. If you have persistent stomach upset, vomit blood or what looks like coffee grounds, or have black, tarry stools, contact your health care provider immediately. It is best to limit or avoid alcohol containing drinks while taking this drug, even with short term use. Many non-prescription products for headaches, pain, arthritis, or sinus pain contain drugs that may cause stomach problems along with alcohol; closely read labels before taking any medicines with alcohol-containing drinks.
Moderate Lifestyle Interaction
Tobacco and Etodolac 400mg Extended-Release Tablet(Etodolac)
Tobacco and Nonsteroidal antiinflammatory drugs (systemic)(Etodolac)
Side effects from Nonsteroidal anti-inflammatory drugs may get worse if you use tobacco-containing products such as cigarettes. If you have persistent stomach upset, vomit blood or what looks like coffee grounds, or have black, tarry stools, contact your health care provider immediately. Many non-prescription products contain NSAIDs; closely read labels before taking any medicines. Eye or Skin products containing NSAIDs should not interact with tobacco.
Moderate Lifestyle Interaction
Marijuana and Etodolac 400mg Extended-Release Tablet(Etodolac)
Marijuana and Nonsteroidal antiinflammatory drugs (systemic)(Etodolac)
Although an interaction is possible, these drugs may be used together. In therory, the actions of Marijuana, Medical may be decreased if you take Nonsteroidal Antiinflammatory Drugs (NSAIDs). However, the importance of this interaction is not known. Patients receiving this drug combination may notice decreased euphoria and heart rate.
Minor Lifestyle Interaction
Food and Etodolac 400mg Extended-Release Tablet(Etodolac)
Food and Etodolac(Etodolac)
Etodolac may be taken with or without food. If you take immediate-release Etodolac without food, you may have a faster response. Try to take Etodolac either with or without food each day.
Pregnancy & Lactation Information
FIRST Trimester
Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.
SECOND Trimester
Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.
THIRD Trimester
Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.
Lactation
Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.
Learning More About
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Patient Experiences with Etodolac
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patient's observations and share your own.
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