Flolan Powder For Solution For Injection 0.5Mg Drug Medication Dosage Information
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Flolan: Powder for solution for injection (0.5mg)

Detailed Information
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What is this Medicine?

EPOPROSTENOL (e poe PROST en ole) is used to treat primary pulmonary hypertension.

In-Depth Information

Flolan 0.5mg Powder for Injection

NDC: 001730517
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Scleroderma (systemic Sclerosis)

Sometimes used for but not FDA approved for the following conditions:
Pulmonary Hypertension

Storage Information
Protect from light
Store in carton
Store between 59 to 77 degrees F
Flolan 0.5mg Powder for Injection
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Reported Side Effects for Flolan 0.5mg Powder for Injection

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Diaphoresis Incidence:
1.0%*
Severity: MILD
Onset: EARLY
Hyperesthesia Incidence:
1.0-12.0%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
1.0%*
Severity: MILD
Onset: EARLY
Paresthesias Incidence:
1.0-12.0%*
Severity: MILD
Onset: DELAYED
Rapid Heart Rate Incidence:
1.0-35.0%*
Severity: MODERATE
Onset: RAPID
Shortness Of Breath Incidence:
2.0%*
Severity: MODERATE
Onset: EARLY
Back Pain Incidence:
2.0%*
Severity: MILD
Onset: DELAYED
Muscle And/Or Bone Pain Incidence:
3.0-35.0%*
Severity: MILD
Onset: EARLY
Slow Heart Beat Incidence:
5.0%*
Severity: SEVERE
Onset: RAPID
Stomach Pain Incidence:
5.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
8.0-83.0%*
Severity: MILD
Onset: EARLY
Chest Pain Incidence:
11.0%*
Severity: MODERATE
Onset: EARLY
Bleeding Incidence:
11.0-19.0%*
Severity: MODERATE
Onset: EARLY
Distressed Incidence:
11.0-21.0%*
Severity: MILD
Onset: EARLY
Nervousness Incidence:
11.0-21.0%*
Severity: MILD
Onset: DELAYED
Low Blood Pressure Incidence:
13.0-16.0%*
Severity: MODERATE
Onset: RAPID
Infection Incidence:
18.0%*
Severity: MILD
Onset: DELAYED
Shaking Incidence:
21.0%*
Severity: MILD
Onset: EARLY
Flushing Incidence:
23.0-58.0%*
Severity: MILD
Onset: RAPID
Hives Incidence:
25.0%*
Severity: MILD
Onset: RAPID
Chills Incidence:
25.0%*
Severity: MILD
Onset: RAPID
Skin Rash Incidence:
25.0%*
Severity: MILD
Onset: EARLY
Fever Incidence:
25.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
32.0-67.0%*
Severity: MILD
Onset: EARLY
Vomiting Incidence:
32.0-67.0%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
37.0-50.0%*
Severity: MILD
Onset: EARLY
Skin Ulcer Incidence:
39.0%*
Severity: MODERATE
Onset: DELAYED
Muscle Pain Incidence:
44.0%*
Severity: MILD
Onset: EARLY
Headache Incidence:
46.0-83.0%*
Severity: MILD
Onset: EARLY
Decreased Appetite Incidence:
66.0%*
Severity: MILD
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Flolan 0.5mg Powder for Injection
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Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Moderate Lifestyle Interaction
Alcohol and Flolan 0.5mg Powder for Injection(Epoprostenol Sodium)
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Alcohol and Antihypertensives(Epoprostenol Sodium)
Although an interaction is possible, Ethanol (alchohol) and Antihypertensive Agents (drugs used to reduce high blood pressure) may be used together. Ethanol or alchohol-containing beverages may increase the effects of Antihypertensive Agents on your blood pressure. If the blood pressure drops too low while taking Ethanol and Antihypertensive Agents, you may become dizzy or feel faint. To limit this interaction, avoid alcohol-containing beverages while taking medicines to lower your blood pressure. Do not stand or sit up too quickly. Contact your prescriber if you have dizziness which does not go away.
Pregnancy & Lactation Information
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FIRST Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

SECOND Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

THIRD Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


Learning More About
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Patient Experiences with Flolan

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