Neupogen Solution For Injection 300Mcg Drug Medication Dosage Information
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Neupogen: Solution for injection (300mcg)

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What is this Medicine?

FILGRASTIM, G-CSF (fil GRA stim) is a granulocyte colony-stimulating factor that stimulates the growth of neutrophils, a type of white blood cell (WBC) important in the body's fight against infection. It is used to reduce the incidence of fever and infection in patients with certain types of cancer who are receiving chemotherapy that affects the bone marrow, to stimulate blood cell production for removal of WBCs from the body prior to a bone marrow transplantation, to reduce the incidence of fever and infection in patients who have severe chronic neutropenia, and to improve survival outcomes following high-dose radiation exposure that is toxic to the bone marrow.

In-Depth Information

Neupogen 300mcg/0.5ml Solution for Injection

NDC: 555130924
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Neutropenia, Chemotherapy-induced Neutropenia, Peripheral Blood Stem Cell (PBSC) Mobilization, Radiation Exposure

Sometimes used for but not FDA approved for the following conditions:
Myelodysplastic Syndrome (MDS), Aplastic Anemia, Ganciclovir-induced Neutropenia

Storage Information
Discard unused portion. Do not store for later use.
Protect from light
Discard product if frozen more than once
Do not freeze
Store in carton until time of use
Protect from direct sunlight
Refrigerate (between 36 and 46 degrees F)
Discard product if it contains particulate matter, is cloudy, or discolored
If frozen, thaw in refrigerator before administration
Neupogen 300mcg/0.5ml Solution for Injection

Reported Side Effects for Neupogen 300mcg/0.5ml Solution for Injection

Shortness Of Breath Incidence:
<13.0%*
Severity: MODERATE
Onset: EARLY
Cough Incidence:
<14.0%*
Severity: MILD
Onset: DELAYED
Skin Redness Incidence:
>2.0%*
Severity: MODERATE
Onset: EARLY
Back Pain Incidence:
2.0-15.0%*
Severity: MILD
Onset: DELAYED
Rash With Pustules Incidence:
>2.0%*
Severity: MILD
Onset: EARLY
High White Blood Cells Incidence:
2.0%*
Severity: MILD
Onset: DELAYED
Constipation Incidence:
>2.0%*
Severity: MODERATE
Onset: DELAYED
Loose Stools Incidence:
>2.0%*
Severity: MILD
Onset: EARLY
Nose Bleed Incidence:
>2.0%*
Severity: MILD
Onset: DELAYED
Antibody Formation Incidence:
3.0%*
Severity: MODERATE
Onset: DELAYED
Hair Loss Incidence:
>5.0%*
Severity: MILD
Onset: DELAYED
Infection Incidence:
>5.0%*
Severity: MILD
Onset: DELAYED
Anemia Incidence:
>5.0%*
Severity: MODERATE
Onset: DELAYED
Removal Of Spleen Incidence:
>5.0%*
Severity: MODERATE
Onset: DELAYED
Decreased Appetite Incidence:
>5.0%*
Severity: MILD
Onset: DELAYED
Joint Pain Incidence:
5.0-9.0%*
Severity: MILD
Onset: DELAYED
Skin Rash Incidence:
5.0-14.0%*
Severity: MILD
Onset: EARLY
Muscle And/Or Bone Pain Incidence:
>5.0%*
Severity: MILD
Onset: EARLY
Feeling Sick Incidence:
>5.0%*
Severity: MILD
Onset: EARLY
Bone Pain Incidence:
5.0-30.0%*
Severity: MODERATE
Onset: DELAYED
Hypoesthesia Incidence:
>5.0%*
Severity: MILD
Onset: DELAYED
Chest Pain Incidence:
5.0-13.0%*
Severity: MODERATE
Onset: EARLY
Fever Incidence:
5.0-48.0%*
Severity: MILD
Onset: EARLY
Weakness Incidence:
>5.0%*
Severity: MILD
Onset: DELAYED
High Blood Pressure Incidence:
>5.0%*
Severity: MODERATE
Onset: EARLY
Inability To Sleep Incidence:
>5.0%*
Severity: MILD
Onset: EARLY
Vomiting Incidence:
>5.0%*
Severity: MILD
Onset: EARLY
Low Platelet Count Incidence:
5.0-38.0%*
Severity: MODERATE
Onset: DELAYED
Fluid Retention Incidence:
>5.0%*
Severity: MODERATE
Onset: DELAYED
Muscle Cramps Incidence:
>5.0%*
Severity: MILD
Onset: DELAYED
Headache Incidence:
10.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
14.0%*
Severity: MILD
Onset: EARLY
Tired Incidence:
>20.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
43.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Pregnancy & Lactation Information
First Trimester

Class 1 - Low Risk

Second Trimester

Class 1 - Low Risk

Third Trimester

Class 1 - Low Risk

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


Learning More About
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