Norvir: Oral capsule, liquid filled

What is this medicine?

What should I tell my health care provider before I take this medicine?

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They need to know if you have any of these conditions:
-diabetes
-hemophilia
-high cholesterol or triglycerides
-liver disease
-an unusual or allergic reaction to ritonavir, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

How should I use this medicine?

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Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine with food. Take your medicine at regular intervals. Do not take your medicine more often than directed. For your anti-HIV therapy to work as well as possible, take each dose exactly as prescribed. Do not skip doses or stop your medicine even if you feel better. Skipping doses may make the HIV virus resistant to this medicine and other medicines. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 1 month old for selected conditions, precautions do apply.

What if I miss a dose?

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If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

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Do not take this medicine with any of the following medications:

-alfuzosin
-certain medicines for irregular heart beat like amiodarone, bepridil, dofetilide, dronedarone, encainide, flecainide, propafenone, quinidine
-cisapride
-conivaptan
-eplerenone
-ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
-lovastatin
-lurasidone
-midazolam
-naloxegol
-pimozide
-ranolazine
-red yeast rice
-rifapentine
-rivaroxaban
-simvastatin
-St. John's wort
-thioridazine
-triazolam
-voriconazole
-ziprasidone

This medicine may also interact with the following medications:

-atovaquone
-bedaquiline
-bosentan
-birth control pills, patches, rings, or injections
-certain medicines for blood pressure, heart disease, irregular heart beat like digoxin, disopyramide, lidocaine, mexiletine, metoprolol, timolol
-certain medicines for cancer like vinblastine, vincristine, dasatinib, nilotinib, venetoclax
-certain medicines for cholesterol like atorvastatin, rosuvastatin
-certain medicines for depression, anxiety, or psychotic disturbances amitriptyline, bupropion, desipramine, fluoxetine, nefazodone, nortriptyline, paroxetine, quetiapine, risperidone, trazodone
-certain medicines for erectile dysfunction like avanafil, sildenafil, tadalafil, vardenafil
-certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole
-certain medicines for pain like fentanyl, meperidine, methadone, tramadol
-certain medicines for seizures like carbamazepine, clonazepam, ethosuximide, divalproex, lamotrigine, phenytoin
-certain medicines for sleep like buspirone, clorazepate, diazepam, estazolam, flurazepam, zolpidem
-certain medicines that treat or prevent blood clots like warfarin
-clarithromycin
-colchicine
-cyclosporine
-dronabinol
-methamphetamine
-other antivirals for HIV or AIDS
-other medicines that prolong the QT interval (cause an abnormal heart rhythm)
-quinine
-rifabutin
-rifampin
-salmeterol
-simeprevir
-sirolimus
-steroid medicines like betamethasone, budesonide, ciclesonide, dexamethasone, fluticasone, methylprednisolone, mometasone, prednisolone, triamcinolone
-tacrolimus
-theophylline

What should I watch for while using this medicine?

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Visit your doctor or health care professional for regular check ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.

HIV is spread to others through sexual or blood contact. Talk to your doctor about how to stop the spread of HIV.

Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control. Women who can still have children must use a reliable form of barrier contraception, like a condom or diaphragm.

This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.

Some products may contain alcohol. Ask your pharmacist or healthcare provider if this medicine contains alcohol. Be sure to tell all healthcare providers you are taking this medicine. Certain medicines, like metronidazole and disulfiram, can cause an unpleasant reaction when taken with alcohol. The reaction includes flushing, headache, nausea, vomiting, sweating, and increased thirst. The reaction can last from 30 minutes to several hours.

What side effects may I notice from receiving this medicine?

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Side effects that you should report to your doctor or health care professional as soon as possible:
-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-fast, irregular heartbeat
-feeling faint or lightheaded, falls
-nausea, vomiting, abdominal pain
-redness, blistering, peeling or loosening of the skin, including inside the mouth

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
-decreased appetite
-diarrhea
-dizziness
-headache
-increased hunger or thirst
-increased urination
-tingling or numbness in the hands or feet or around the mouth
-unusually weak or tired
-weight gain around waist, back, or thinning of face, arms, legs