Phenergan Rectal Suppository 12.5Mg Drug Medication Dosage Information
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Phenergan: Rectal suppository (12.5mg)

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Phenadoz 12.5mg Rectal Supp
Paddock Laboratories Inc, a Perrigo Family
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Phenergan 12.5mg Rectal Supp
Wyeth Pharmaceuticals Inc, a subsidiary of Pfizer Inc

What is this Medicine?

PROMETHAZINE (proe METH a zeen) is an antihistamine. It is used to treat allergic reactions and to treat or prevent nausea and vomiting from illness or motion sickness. It is also used to make you sleep before surgery, and to help treat pain or nausea after surgery.

In-Depth Information
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Phenergan 12.5mg Rectal Suppository

NDC: 400760318
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Sedation Induction, Post-operative Nausea/vomiting (PONV) Prophylaxis, Post-operative Nausea/vomiting (PONV), Motion Sickness, Procedural Sedation, Nausea/vomiting, Pruritus

Sometimes used for but not FDA approved for the following conditions:
Pregnancy-induced Nausea/vomiting, Hyperemesis Gravidarum

Storage Information
Refrigerate (between 36 and 46 degrees F)
Phenergan 12.5mg Rectal Suppository

Reported Side Effects for Phenergan 12.5mg Rectal Suppository

Dystonic Reaction Incidence:
1.0%*
Severity: MODERATE
Onset: DELAYED
Pseudoparkinsonism Incidence:
1.0%*
Severity: MODERATE
Onset: DELAYED
Confusion Incidence:
3.2%*
Severity: MODERATE
Onset: EARLY
Inability To Sleep Incidence:
3.2%*
Severity: MILD
Onset: EARLY
Restlessness Incidence:
4.0-14.0%*
Severity: MODERATE
Onset: DELAYED
Excitability Incidence:
9.7%*
Severity: MODERATE
Onset: EARLY
Dry Mouth Incidence:
9.7%*
Severity: MILD
Onset: EARLY
Drowsiness Incidence:
38.0-71.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Phenergan 12.5mg Rectal Suppository

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Alcohol and Phenergan 12.5mg Rectal Suppository(Promethazine Hydrochloride)
Alcohol and Phenothiazines(Promethazine Hydrochloride)
It is recommended that you avoid Alcoholic drinks while you are taking this medication. Alcohol can increase the risk of side effects, such as drowsiness and dizziness. Do not drive or operate machinery if you are drinking alcohol-containing beverages. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.
Major Lifestyle Interaction
Marijuana and Phenergan 12.5mg Rectal Suppository(Promethazine Hydrochloride)
Marijuana and Phenothiazines(Promethazine Hydrochloride)
It is recommended that ingestion, smoking, or inhalation of marijuana be avoided if you are treated with this drug. Marijuana may increase the risk for relapse or an increase in your mood and behavior symptoms. Marijuana may also interfere with the efficacy of your medication in treating your condition. If you continue to use marijuana, promptly get medical assistance if you experience unusual changes in moods or behaviors of any type. Be aware that sedation may occur and you should not drive or operate machinery or perform other hazardous tasks while under the influence of these medications.
Moderate Lifestyle Interaction
Tobacco and Phenergan 12.5mg Rectal Suppository(Promethazine Hydrochloride)
Tobacco and Phenothiazines(Promethazine Hydrochloride)
Tobacco smoking may reduce the effectiveness of this drug in treating your condition; Tobacco smoke contains substances that speed the removal of this drug from the body. Alternatively, if you take this drug and suddenly stop Tobacco smoking, you may feel more drowsy or tired, or may experience confusion, dizziness, difficulty in movement or other side effects. If you will stop smoking, use care in driving or operating machinery until you know how this drug will affect you. Make sure your prescriber is aware that you smoke Tobacco or if you plan to stop smoking. Report any unusual side effects promptly.
Pregnancy & Lactation Information
First Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Second Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Third Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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