Piperacillin, Tazobactam Powder For Solution For Injection 2.25G Drug Medication Dosage Information
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Piperacillin, Tazobactam: Powder for solution for injection (2.25g)

Detailed Information
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What is this Medicine?

PIPERACILLIN; TAZOBACTAM (pi PER a sil in; ta zoe BAK tam) is a penicillin antibiotic. It is used to treat certain kinds of bacterial infections. It will not work for colds, flu, or other viral infections.

In-Depth Information
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Piperacillin/Tazobactam 2.25g Powder for Injection

NDC: 007813110
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Peritonitis, Pneumonia, Intraabdominal Infections, Intraabdominal Abscess, Nosocomial Pneumonia, Diabetic Foot Ulcer, Pelvic Inflammatory Disease (PID), Cellulitis, Skin And Skin Structure Infections, Endometritis, Appendicitis, Lower Respiratory Tract Infections, Community-acquired Pneumonia

Sometimes used for but not FDA approved for the following conditions:
Bacteremia, Febrile Neutropenia, Pyelonephritis, Cystic Fibrosis, Septicemia, Urinary Tract Infection (UTI), Surgical Infection Prophylaxis

Storage Information
Reconstituted product is stable for up to 24 hours at room temperature and 48 hours under refrigeration
Store unreconstituted product at 68 to 77 degrees F
Piperacillin/Tazobactam 2.25g Powder for Injection
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Reported Side Effects for Piperacillin/Tazobactam 2.25g Powder for Injection

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Anaphylactoid Reactions Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Elevated Hepatic Enzymes Incidence:
<1.4%*
Severity: MODERATE
Onset: DELAYED
Eosinophilia Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Flushing Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Injection Site Reaction Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Irritated Blood Vessels Incidence:
<1.3%*
Severity: MODERATE
Onset: RAPID
Bruises Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Kidney Failure Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Severe Allergy Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Anemia Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Joint Pain Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Nose Bleed Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Low Blood Sugar Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Low Potassium Levels Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Low Blood Pressure Incidence:
<1.3%*
Severity: MODERATE
Onset: RAPID
Low Platelet Count Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Mouth Ulcers Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Pseudomembranous Colitis Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Muscle Pain Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Stomach Pain Incidence:
1.3-1.8%*
Severity: MILD
Onset: EARLY
High Platelet Count Incidence:
1.4%*
Severity: MODERATE
Onset: DELAYED
Yeast Infection Incidence:
1.6-3.9%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
1.9-3.3%*
Severity: MILD
Onset: EARLY
Fever Incidence:
2.4-3.2%*
Severity: MILD
Onset: EARLY
Vomiting Incidence:
2.7-3.3%*
Severity: MILD
Onset: EARLY
Itching Incidence:
3.1-3.2%*
Severity: MILD
Onset: RAPID
Blistery Rash Incidence:
3.9-4.2%*
Severity: MODERATE
Onset: EARLY
Rash With Pustules Incidence:
3.9-4.2%*
Severity: MILD
Onset: EARLY
Hives Incidence:
3.9-4.2%*
Severity: MILD
Onset: RAPID
Skin Rash Incidence:
3.9-4.2%*
Severity: MILD
Onset: EARLY
Inability To Sleep Incidence:
4.5-6.6%*
Severity: MILD
Onset: EARLY
Headache Incidence:
4.5-7.7%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
5.8-6.9%*
Severity: MILD
Onset: EARLY
Constipation Incidence:
7.7-8.4%*
Severity: MODERATE
Onset: DELAYED
Loose Stools Incidence:
11.3-20.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Pregnancy & Lactation Information
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FIRST Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

SECOND Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

THIRD Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Lactation

Compatible - This drug is generally safe to take by nursing mothers.


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