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Differin Adapalene Gel 0.1% Acne Treatment

Differin Gel
reg. $15.49
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1.6 Ounces
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Differin Adapalene Gel 0.1% Acne Treatment
.5 OZ, .08 lbs. Item # 213858
Differin Gel contains a Rx-strength acne-fighting retinoid. It clears breakouts where they start (deep in the pores), prevents acne before it begins, and as a result, restores skin’s texture and tone.
  • Clear and prevent acne with an Rx-strength retinoid
  • Fights the main causes of acne by regulating skin cell turnover & reducing inflammation deep in the skin to clear and prevent pimples, blackheads and clogged pores
  • Differin Gel can reduce up to 87% of acne in just 12 weeks (Cunliffe et al 1998, Galderma Laboratories)
  • Effectively treats acne to restore your skin’s natural tone & texture
  • The retinoid in Differin heals current acne and stops new acne from forming

Differin Ingredients

Active ingredient: Adapalene 0.1% (retinoid)* *read consumer information leaflet.

Inactive ingredients: carbomer 940, edetate disodium, methylparaben, poloxamer 182, propylene glycol, purified water and sodium hydroxide.

May contain hydrochloric acid to adjust pH.


Directions: Adults and children 12 years of age and older:

  • use once daily
  • clean the skin gently and pat dry before applying the product
  • cover the entire affected area with a thin layer. For example, if your acne is on the face, apply the product to the entire face.

Do not use more than one time a day.

  • Applying more than directed will not provide faster or better results, but may worsen skin irritation.

Children under 12 years of age: ask a doctor.


Warnings: For external use only.

Do not use

  • on damaged skin (cuts, abrasions, eczema, sunburn)
  • if you are allergic to adapalene or any of the ingredients in this product.
  • If pregnant or breast-feeding, ask a doctor before use.

When using this product

  • limit sun exposure, including light from tanning beds, and use sunscreen when going outdoors
  • do not wax to remove hair in areas where the product has been applied during the early weeks of use, your acne may appear to worsen before it improves (this is normal);
  • continue using as directed, unless you get irritation that becomes severe irritation (redness, itching, dryness, burning) is more likely to occur: in the first few weeks of use if using more than one topical acne medication at a time but irritation usually lessens with continued use of this product it may take up to 3 months of once daily use to see results avoid product contact with eyes, lips, and mouth.

If contact occurs, immediately flush the area with water. Wash hands after use.

Stop use and ask a doctor if you become pregnant, or are planning to become pregnant, while using the product you have symptoms of an allergic reaction (such as itching, rash, hives, swelling of the lips, eyelids, and shortness of breath, irritation becomes severe you see no improvement after 3 months of once daily use.

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

What Is Differin Gel?

Differin Gel is an FDA-approved prescription strength retinoid acne treatment. It contains the only FDA approved retinoid that is available over the counter.

What Is Differin Used For?

Differin Gel is used to treat acne. Differin Gel is designed to treat pimples, including both blackheads and whiteheads, and may also help to reduce redness and inflammation.

How Does Differin Work?

Differin contains 0.1 percent adapalene, a powerful retinoid that helps fight acne, including blackheads and whiteheads deep inside your pores, preventing pimples before they start and treating existing pimples on the surface at the same time. Adapalene is anti-inflammatory, which helps to reduce redness and swelling. Adapalene also assists in regulating skin cell turnover, which helps keep pores from clogging up. Differin uses an oil-free, alcohol-free, and fragrance-free water-based formula that is designed to be gentle on skin.

How to Use Differin Gel

You should use Differin Gel one time a day, either as part of your morning or evening skin care routine. For best results, you should wash skin with a gentle, non-drying cleanser first. Pat your skin dry, then apply a thin, even layer of Differin Gel. Differin Gel is not a spot treatment, so you should apply the product to your entire face. You may choose to follow up with a moisturizer to help decrease dryness.

How Long Does Differin Take to Work?

Differin Gel starts working immediately, but it may take some time to see results. Some people may see results in as little as 2 weeks, but the time it takes to see significant results varies from person to person.

Are There Differin Gel Side Effects?

You may notice a few mild side effects during the time it takes your skin to adapt to the treatment. Common side effects include: dryness, redness, irritation, and burning or stinging. Side effects generally peak around week 2 of using Differin and start to subside around week 4. However, if irritation is severe or prolonged, you should stop using Differin and talk to your doctor.

Where to Buy Differin

You can buy Differin Gel at most local CVS stores or online. Differin Gel is an over the counter retinol, meaning that you do not need a prescription to purchase it. If you are curious about other people’s experiences, you may want to read the Differin reviews posted on this page by customers just like you.

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