CVS Pharmacy at 1500 Spruce Street Philadelphia, PA 19102

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Store & Photo Hours

  • Monday through Friday Open 24 hours
  • Saturday Open 24 Hours
  • Sunday Open 24 Hours

Pharmacy Hours

  • Monday through Friday 8:00 AM to 9:00 PM
  • Saturday 8:30 AM to 6:00 PM
  • Sunday 8:30 AM to 6:00 PM


  • Monday through Friday 8:30 AM to 7:30 PM
  • Saturday 9:00 AM to 5:30 PM
  • Sunday 9:00 AM to 4:30 PM
  • Practitioners take a required lunch break. Times vary. View Hours and Services

What services does this CVS offer?

About this Pharmacy & Drug Store


When you are in the downtown area, you have more important things to do than run errands. At our CVS Pharmacy® we offer convenience and affordability on a wide range of services and products. Located across the street from the Kimmel Center for the Performing Arts, our 24-hour store is in the perfect place to grab anything from medication to a snack.


Pharmacy solutions


As you should expect from a pharmacy we can meet all your prescription needs, but we are also so much more. Our knowledgeable staff can answer your questions about side effects and drug interactions. You can also get this information by signing in to your personal CVS account. Download our mobile app and use it to place orders online, manage prescription refills and transfer scripts from other locations.


Have a cough and sore throat? Find a selection of over-the-counter cold and flu medicine to help you feel better. We also have remedies for asthma, allergies, skin conditions, cuts, sprains, muscle aches and feminine issues.


MinuteClinic® services


If you feel on OTC medication won't cut it or you want a professional opinion about why you do not feel well, make an appointment or stop in to our MinuteClinic®. Our walk-in clinic is a convenient alternative to a visit to your physician's office, and the proximity of our pharmacy makes it easy to get your meds filled and get home to rest.


Our physician assistants and nurse practitioners are able to diagnose, provide treatment and/or provide referrals to other health care providers for both children and adults. Some common reasons customers take advantage of our services include:


  • Minor illnesses such as sinus infection, flu, ear infection, heartburn and nausea
  • Minor injuries such as sprains, bruises, bumps, minor burns and insect bites
  • Skin conditions
  • Women's health issues
  • Wellness physicals
  • Vaccinations
  • Travel health


You can either walk in or go online to make an appointment. We accept most insurance plans, and we offer convenient payment options.


Other retail offerings


If you run out of toilet paper in the middle of the night or you want a snack to fortify you for the afternoon, we can help you out. Our drug store offers a wide selection of household products and convenience items so you can do your shopping all in one place.


Peruse our grocery department for premade meals, fresh ingredients and basic essentials. We also carry a variety of beverages and snacks. Shop for cleaning supplies, paper towels and diapers. Other products we carry include cosmetics, hair and skin care, office supplies, cards and wrapping paper, gifts, seasonal items and games.


For photo printing, our full-service photo department can help in a number of ways, including:


  • Custom prints or enlargements
  • Calendars or photo albums
  • Photo cards
  • Wall art
  • Passport photos


Stop in to our drug store today


Look at our weekly ad to see what specials we have going on. Stop in and get all your shopping done, and make sure to use your ExtraCare® rewards to save money and build up points. We can be found at the corner of Spruce St and S 15th St and reached at 215-790-3290.