STORE OPEN Until 10:00 PM

CVS Pharmacy at 500 West 42nd Street On The Corner Of 42nd St. New York, NY 10036

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Store & Photo Hours

  • Thanksgiving Hours 7:00 AM to 10:00 PM
  • M-F 7:00 AM - 10:00 PM
  • Sat 7:00 AM - 10:00 PM
  • Sun 7:00 AM - 10:00 PM

Pharmacy Hours

  • Thanksgiving Hours 9:00 AM to 2:00 PM
  • M-F 8:00 AM - 9:00 PM
  • Sat 9:00 AM - 6:00 PM
  • Sun 9:00 AM - 6:00 PM

What services does this CVS offer?

About this Pharmacy & Drug Store


Your life doesn’t pause outside of traditional business hours or when a store closes for the night. Thus, it can be especially frustrating when you need pain medicine in the middle of the night or remember on your way to work at four a.m. that your best work pal has a birthday that day.


Fortunately, many CVS Pharmacy® locations in New York are open 24 hours. That includes our retail store at 500 West 42nd Street. So, no matter the time of day, we’re open to help with the problems and joys that life throws your way. If it’s midnight and you’re wondering, “Where is a pharmacy near me?” we’re here.


Pharmacy options


Our pharmacy itself has generous hours but is not open 24 hours like the rest of the store is. Still, you can refill, manage and track prescriptions online or on your smartphone, and stop by seven days a week during open hours. We also offer immunizations and flu shots.


Store options


You enjoy the ability to purchase over-the-counter medications, Plan B tablets, food, soda, shampoo and much more at your convenience. If you are a night owl or prefer to avoid crowds, you can shop in the wee hours of the night. We also have SNAP products that you can purchase using your EBT card.


We’re in Hell’s Kitchen near the Garment District and the Theater District-Times Square, so if you are a tourist rather than a resident, we have you covered on the little essentials you may have left back home. Ditto if you need an energy drink or food fuel to plow through more of what wonderful New York has to offer.


Photo options


It doesn’t matter if you are a resident or a visitor, you probably enjoy taking photos and having physical copies of them. We offer photo printing, and if you want custom prints, you can do that too. For example, you can tailor an item such as a photo blanket or photo beach towel online, have it shipped to the store for free and pick it up in about seven to 11 business days.


Ask many New Yorkers what they love to do, and a good portion will say, “Travel!” So when Mexico, Britain, Australia, South Korea or another wonderful country beckons, you can get passport photos done here. Our technicians know how to take these pictures so that they follow federal rules.


Online options


Of course, just because you can visit our store 24 hours a day does not mean you necessarily want to. Good thing we have a robust online selection where you can shop for a wide range of quality products and enjoy superb savings, especially with ExtraCare® rewards (use them in stores too!). To cover all of your bases in savings, you can sign up for weekly ads and email exclusives and download the app.


Come see us


We’re here ready to serve you 24 hours a day, whether it is groceries, gifts, pads, cosmetics, or a greeting card that you need. You can call us at 212-244-4285 if you have questions before stopping by the store.