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Some things to know about meal replacement shakes

The benefits and potential downsides of meal replacement shakes.

Published: October 13, 2025 | 6 minutes to read

Written by: Max Schochet

Person drinks a homemade meal replacement shake in their kitchen.

Meal replacement shakes might seem like the ultimate nutrition shortcut. They’re tasty, easy to drink and often marketed as a quick way to get protein, vitamins and minerals. The convenience of drinkable food can be hard to resist.

But there’s more to consider beneath the surface. Meal replacement shakes aren’t always the healthiest choice compared to whole foods. But they can still be useful depending on someone’s goals. Here’s what people should keep in mind before buying.

In this article:

What are meal replacement shakes?

The meal replacement shakes discussed in this article are the ones that come ready to drink and are designed to stand in for a low-calorie meal or snack. They’re an easy way to get a mix of protein, carbs and healthy fats, plus vitamins and minerals. However, meal replacement products aren’t clearly defined or regulated in the U.S., and how they’re named depends on how they’re marketed.

What are the benefits of meal replacement shakes?

One of the key advantages of meal replacement shakes is their convenience. They serve as a quick and easy option for breakfast or lunch. They’re also a solid choice to help fill nutritional gaps when a traditional meal isn’t possible.

What are the potential downsides of meal replacement shakes?

While meal replacement shakes can be great for some, there may be downsides people should be aware of:

  • Not as healthy as regular food. Even if they're fortified or chockful of healthy ingredients, meal replacement shakes still won't contain everything a whole food source might have.
  • Side effects from too much protein. Too much protein may increase the risk of kidney stones. It may also cause dehydration and further kidney damage in those with kidney disease.
  • May contain lots of sugar. Meal replacement shakes may contain lots of sugar. Too much added sugar in someone’s diet can contribute to weight gain, obesity, type 2 diabetes and heart disease.
  • May lead to weight gain. People who eat a full meal and then drink a meal replacement shake may end up consuming extra calories. This may lead to weight gain along with other complications associated with obesity, such as high blood pressure and diabetes.
  • Long-term side effects are still unknown. Researchers still don’t know much about the long-term side effects of a high-protein diet from supplements.

What should people look for in a meal replacement shake?

If someone is looking for personalized nutrition advice, it is recommended that they speak to a dietician or other health care provider before changing their diet.

There are a few key things to look for in a meal replacement shake:

  • No more than 400 calories per serving (for meal replacement)
  • No more than 200 calories per serving (for snacking)
  • 2 grams or less of saturated fat
  • 5 grams of sugar or fewer
  • No trans-fat or partially hydrogenated oils

5 meal replacement shakes to consider

A brown bottle of chocolate-flavored Core Power Complete Protein by Fairlife.

1. Core Power Complete Protein by Fairlife

Core Power Complete Protein is a high-protein milkshake made with simple ingredients and ultra-filtered Fairlife milk. It packs 26 grams of protein with all 9 essential amino acids included to help build lean muscle and support workout recovery. This meal replacement shake is available in chocolate and vanilla.

2. Orgain Organic Nutrition Shakes

These organic, grass-fed protein shakes are packed with 16 grams of protein, 21 vitamins and minerals, and a blend of organic fruits and veggies. They’re creamy and work as a meal replacement, a quick snack or a boost when someone needs high-quality nutrition on the go. Plus, they’re gluten-free, soy-free, non-GMO and third-party tested for quality.

A white and green bottle of an Orgain Organic Nutrition shakes

2. Orgain Organic Nutrition Shakes

These organic, grass-fed protein shakes are packed with 16 grams of protein, 21 vitamins and minerals, and a blend of organic fruits and veggies. They’re creamy and work as a meal replacement, a quick snack or a boost when someone needs high-quality nutrition on the go. Plus, they’re gluten-free, soy-free, non-GMO and third-party tested for quality.

A white, red and blue bottle of a vanilla-flavored Premier Protein shake.

3. Premier Protein High Protein Shake

Premier Protein’s vanilla shake delivers 30 grams of protein at just 160 calories and only 1 gram of sugar per 11 fluid ounce bottle. It has 24 essential vitamins and minerals and is low in fat.

4. Quest Nutrition Protein Shake

Quest Vanilla protein shakes are made with just 11 ingredients and contain 30 grams of protein, only 3 grams of carbs and just 1 gram of sugar. They’re naturally flavored and non-GMO.

A white and gray bottle of a Quest Nutrition protein shake.

4. Quest Nutrition Protein Shake

Quest Vanilla protein shakes are made with just 11 ingredients and contain 30 grams of protein, only 3 grams of carbs and just 1 gram of sugar. They’re naturally flavored and non-GMO.

A brown and green bottle of dark chocolate-flavored OWYN plant-based drink.

5. OWYN Protein 100 Percent Plant-Based Drink

These vegan, gluten-free shakes deliver 20 grams of plant protein with all 9 essential amino acids and natural branched-chain amino acids (BCAAs) to support muscle recovery and daily wellness. They contain fiber, vegan omega-3s and a superfood blend of kale, spinach and broccoli. They’re made without dairy, soy, nuts or artificial ingredients. They’re not genetically modified (GMO), and these drinks are available in dark chocolate and vanilla flavors.

Can meal replacement shakes help someone lose weight?

Eating more protein than usual may help reduce body fat, preserve muscle, increase fullness and support weight loss. However, the evidence is limited. Replacing meals with protein shakes may also lower daily calorie intake and aid weight loss. But eventually, people will need to return to solid food. And when they do, some of the lost weight may come back.

Getting enough protein is important. But it’s exercise — not extra protein — that can help build muscle. Weight loss can be achieved when people pair it with burning more calories than they consume.

Need helping losing weight? Reach out to a health care provider or connect with the board-certified providers at MinuteClinic location for a personalized weight loss plan.

Can meal replacement shakes be a long-term substitute for all meals?

Meal replacement shakes can be super convenient, but they’re not meant to take the place of whole foods like fruits and veggies. Most health care providers don’t recommend relying on them all the time to meet protein needs — they’re better used as a supplement, not as a full-time substitute.

Key takeaways

Meal replacement shakes can be a convenient way to help get some nourishment while on the go or before a workout. For individuals who already get sufficient nutrition from their regular diet, replacing all meals with shakes isn’t recommended. These products often lack key nutrients found in whole foods, which can lead to nutritional gaps over time. However, some individuals with certain health conditions — or those who have difficulty eating regular food — may rely on meal replacement shakes to help meet their nutritional needs. While meal replacement shakes can be useful in certain situations, it’s best to check with a health care provider before using them.

Frequently asked questions (FAQs)

In general, people should get about 15 to 30 grams of protein at each meal. Research shows that eating more than 40 grams of protein at once doesn’t help the body more than eating 15 to 30 grams.

Most people in the U.S. get enough protein. In fact, they often eat more than the recommended amount, particularly from meat, poultry and eggs. Even athletes typically meet their protein needs through regular food intake. If someone is already eating a healthy diet, they likely won’t need to add extra protein through protein shakes or other supplements. However, some individuals may still benefit from increasing their protein intake:

  • Older adults
  • People who exercise regularly
  • Pregnant people

If someone is looking for personalized nutrition advice about protein, it is recommended that they speak to a dietician or other health care provider to determine their protein intake recommendations.

This content is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment. Consult your health care provider if you have any questions about medications, vitamins or supplements you may be considering or changes to your wellness or health care routines.

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