A new standard in sensitive-friendly beauty choices, backed by science.

Introducing SkinSAFE: developed with the Mayo Clinic, now in partnership with CVS®.

Using SkinSAFE app while shopping at CVS.

What is SkinSAFE?

Developed in partnership with the Mayo Clinic, SkinSAFE is a database of beauty and skin care products that are listed based on ingredients, so you can choose products that avoid potential skin allergens or irritants.* This is especially important if you have allergic contact dermatitis: SkinSAFE also identifies the 11 groups of top allergens estimated to affect 49% of all sensitive skin cases.

Top 11 groups of allergens SkinSAFE has estimated to affect 49% of all sensitive skin cases, including fragrance, methylisothiazolione, formadelhyde, benzalkonium chloride, methyldibromo glutaronirtrile, nickel, potassium dichromate, cobalt chloride, benzophenone 4, neomycin and bacitracin.

How does SkinSAFE work?

The SkinSAFE product database is updated daily by its in-house team, which includes former Mayo Clinic nurses who scan and review each item. This database contains thousands of ingredients and products listed for your information. SkinSAFE is accessible and available to use for free on their site,, and through the SkinSAFE app found in the App Store and on Google Play. With SkinSAFE, you can:

  • Easily search and browse thousands of products safe for your skin
  • Create a personalized list of your favorite products
  • Instantly scan products while shopping at CVS to learn more
  • Quickly submit products not already rated by SkinSAFE
  • Avoid the top most common allergy-causing ingredients and filter out allergens you wish to exclude
  • Get a Personal Allergy Code (PAC) from your doctor to find products safe for your specific skin allergies
Look for our "Sensitive Friendly" badges on 250+ products that SkinSAFE has identified as made without common allergens and irritants.
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*The SkinSAFE program is not owned or operated by CVS. The SkinSAFE "Sensitive Friendly" badge is based on SKINSAFE reviews of product ingredients and does not represent a guarantee that products have been tested to confirm the absence of any particular allergen or irritant.