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Epinephrine injection pen refills

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Need to know more about epinephrine injection pen refills? We’ve got you covered.

Epinephrine (adrenaline) is a medication that opens airways in the lungs and raises blood pressure. This reverses the effects of a serious allergic reaction,* also known as anaphylaxis.

Anaphylaxis can cause someone to go into shock. Their blood pressure drops and their airways restrict, which can block their ability to breathe.* This happens when a person has a serious allergy to certain foods, insects, medications, plants and other causes.

Using an epinephrine injection pen (EpiPen) on someone experiencing anaphylaxis may save their life. Always call 911 immediately after an injection.

Looking for information about epinephrine injection refills? We have you covered.

People who experience serious allergic reactions should keep two doses of epinephrine injections (EpiPens) on them, in case a severe allergic reaction re-occurs. Medications expire, so be sure to keep an eye on the expiration date and get a refill when needed.

Getting help

A MinuteClinic provider can review a person’s medical history and refill their prescription. They can also answer any questions about allergic reactions and epinephrine.

  1. You may have to answer a few questions to help us prepare for your visit prior to scheduling your appointment.
  2. Check-in varies depending on how you scheduled your appointment:

    If you made your appointment online:
    Check in using the email or text message we sent to confirm your appointment. If you prefer to check in using the electronic kiosk, make sure you have your confirmation code.

    If you made your appointment in the clinic:
    Sign in at the electronic kiosk.

    If you made a MinuteClinic Virtual Care® appointment:
    To join your virtual visit, use the link in the email or text message we sent you to confirm your appointment. Please join 15 minutes before your scheduled visit time. You will need your date of birth and ZIP code to join the visit.

  3. When it's time for your appointment, a provider will call your name.
  4. Your provider will conduct a thorough examination based on your reason for visit, presenting symptoms and health history. Charges will be based on examination and services provided during the visit.
  5. At the end of your visit, you are provided with a visit summary, receipt and educational material. At your request, we can send your primary care provider information about your visit.

Frequently asked questions

Because over-the-counter allergy medications like antihistamines don’t raise blood pressure or reverse airway swelling.

People who experience serious allergic reactions should carry two epinephrine auto-injectors with them at all times. Always follow the package directions or directions given by a health care provider when using an injector.

Allergy symptoms occur when the immune system detects an allergen in the body. It produces antibodies to protect against that specific allergen. The antibodies trigger the release of immune system chemicals when a person is exposed to the allergen in the future.* Depending on the allergen involved, symptoms can range from mild to severe.

Common allergy triggers include the following:*

  • Airborne allergens, such as animal dander, dust, mites, mold, and pollen.
  • Certain foods, particularly eggs, milk, peanuts, shellfish, soy, tree nuts and wheat.
  • Insect stings from bugs like ants, bees, hornets and wasps.
  • Latex or other materials.
  • Medication, particularly penicillin and penicillin-based antibiotics.

Allergic reactions range in severity. Not all allergic reactions require an epinephrine injection.

A MinuteClinic provider can review a person’s medical history and refill their prescription. They can also answer any questions about allergic reactions and epinephrine.

IMPORTANT! PLEASE READ: This material is for reference only and should not be used to determine treatment for specific medical conditions. Please visit a health care provider for evaluation, diagnosis and treatment of any symptoms you may be experiencing. If you're experiencing a medical emergency, please dial 911 or visit your local emergency department.

 

REFERENCES USED AS SOURCES FOR THIS PAGE:

  • *FOR REVERSES THE EFFECTS OF A SERIOUS ALLERGIC REACTION SOURCE: Cleveland Clinic. Epinephrine (adrenaline). Updated March 27, 2022. 

  • *FOR BLOCK THEIR ABILITY TO BREATHE SOURCE: Mayo Clinic. Anaphylaxis. Updated April 16, 2025.

  • *FOR EXPOSED TO THE ALLERGEN IN THE FUTURE SOURCE: Mayo Clinic. Allergies. Updated August 24, 2024.

  • *FOR COMMON ALLERGY TRIGGERS LIST SOURCE: American College of Allergy, Asthma and Immunology. Anaphylaxis. Updated March 24, 2025.