STORE OPEN Until 11:00 PM

CVS Pharmacy at 3300 S Orange Blossom Trl Kissimmee, FL 34746

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Store & Photo Hours

  • Mo-Th 8:00 AM - 11:00 PM
  • Fr 8:00 AM - 12:00 AM
  • Sat 8:00 AM - 12:00 AM
  • Sun 8:00 AM - 11:00 PM

Pharmacy Hours

  • M-F 8:00 AM - 9:00 PM
  • Sat 9:00 AM - 6:00 PM
  • Sun 10:00 AM - 6:00 PM

What services does this CVS offer?

About this Pharmacy & Drug Store


Maintaining your health can be a challenge when you are recovering from illness or injury. When you need to fill a prescription or find over-the-counter relief, come by CVS Pharmacy® at 3300 South Orange Blossom Trail. We'll help you find what you need quickly so you can get back to feeling your best as soon as possible.


24/7 store with a full-service pharmacy and immunizations


Our store at 3300 South Orange Blossom Trail is open 24 hours every day of the week and features extended pharmacy operating hours. Day or night, it's easy to find our location near the intersection of South Orange Blossom Trail and Pleasant Hill Road, near Oaks National Golf Club. If you're in a hurry, take advantage of our Drive-Thru Pharmacy option.


Quick prescription service isn't all you'll find at our Kissimmee location. You don't need an appointment for immunizations at our walk-in clinic. Just stop by for a flu shot or other CDC-recommended vaccine administered by our certified immunizing pharmacists.


Convenient prescription management at


If you want to manage automatic refills or order a new prescription from your home or office, you can create a personal CVS account at our website. Once you sign in, you can access your current and past orders, find information on drug interactions and use our Pill Identifier tool. We also make it easy to manage your account from your mobile device. When you download our app on your tablet or smartphone, you can transfer prescriptions, browse the weekly ad and link your ExtraCare® rewards account with just a few simple taps.


Household essentials, cosmetics and seasonal gifts


At CVS Pharmacy®, we know having a busy schedule makes it a challenge to drive all over town completing errands. That's why we make it easy to stock up on the basics you need while you're picking up your prescription. Along with over-the-counter medicine, you can find cosmetics, toiletries, dental-care products, baby supplies and seasonal gifts.


You can also fill your pantry and fridge with selections from our variety of snacks, treats and beverages. If you're a SNAP participant, you can pay for eligible purchases with your EBT card at our 3300 South Orange Blossom location.


Passport photo service and custom prints


Do you need passport photos to prepare for an international trip? Want to turn the digital pictures from your last vacation into high-quality custom prints? Come by our photo center. Our trained technicians can help you upload your digital files and choose the right printing options, such as:


  • Memory books
  • Calendars
  • Personalized gifts
  • Enlargements
  • Wallet-sized photos


Affordable self-care products with OTC Health Services


Part of living a healthy lifestyle is about managing your own care. CVS Pharmacy® makes it easy by working with health providers that cover over-the-counter medicines and supplies. With the OTC Health Services program, you can find covered items, including vitamins, testing equipment and monitoring supplies, easily at our store's dedicated OTC section. If you prefer, you can shop over the phone or online instead.


Come by our drug store today


Whether you need a flu shot or a prescription refill, CVS Pharmacy® can help. Come by our store today, or call 407-944-0072 to speak to a pharmacist.

Pick up and drop off UPS® packages

Offering extra flexibility, convenience, and safety to all your packaging and shipment needs, our CVS store is now an active UPS Access Point. Drop-off and pick up your packages with UPS tracking available, so you can be sure it’s arrived. We’ll hold packages for up to 7 days, so you can pick them up on your schedule. For UPS package drop-offs, we accept pre-labeled, prepaid packages for 5 to 7 day ground and air delivery. UPS will collect all packages within 24 hours. Find more UPS Access Point information for packages that may not qualify for shipment from our location.