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CVS® now offers FREE in-store pickup!

Currently available at select stores.

921 Main Street Kansas City, MO 64105

Store #8592 Get directions
Set as myCVS store 816 842-2514

Closed 1:30-2 daily for lunch

Services at this store

COVID-19 Vaccines

Get vaccinated for COVID-19 today. Schedule your vaccine ahead of time so you can get out faster.

CVS Photo

At CVS Photo, you can turn your photos into gifts and pieces of art that will be cherished for years to come.

About this pharmacy & drug store

Main Street CVS Pharmacy

The CVS Pharmacy at 921 Main Street is a Kansas City pharmacy that is the place to go for household supplies and quick snacks. The Main Street store is your one-stop shop for first aid supplies, vitamins, cosmetics, and groceries. Its easy-to-access location has made this Kansas City pharmacy a local fixture.

It's wonderful to be able to find all the healthcare and household products you need in one place, but it's equally nice to get your daily necessities at low prices. The Kansas City CVS Pharmacy is your local store for discounts on the things you use regularly. Looking for even better deals? Sign up for an ExtraCare® Membership and score ExtraCare® Rewards on select products. You'll also be added to our email list and receive special offers, personalized coupons, and sales notifications.

Shopping at the Nearby Kansas City CVS Pharmacy

Main Street CVS Pharmacy is happy to be a vital piece of the Kansas City . We're prepared to aid locals looking for a spot to find everyday products without extra effort. This Kansas City CVS Pharmacy is glad to help keep the people of Kansas City well by filling prescriptions and offering over-the-counter supplements and vitamins at great prices.

You can buy personal care items, vitamins, cosmetics, and many other products in an easy-to-navigate store that will allow you to get on your way in no time. Stocking up on everyday products is a piece of cake.

How to Get to Main Street CVS Pharmacy

This CVS Pharmacy is the spot to pick up prescription medicine, groceries, and more in Kansas City. Pick up all your weekly provisions without leaving the comfortable confines of your immediate area. If you can't get a ride or don't have a car, no problem. The Main Street CVS Pharmacy is near the Library on Main at 9th St NB transit station, only 0.02 miles away. Just pay the fare and you'll be on your way.

Main Street CVS Pharmacy FAQ

Does Main Street CVS Pharmacy have UPS drop-off?

No, the Main Street CVS Pharmacy is not a UPS access point, but East Independence Avenue CVS Pharmacy located about 2 miles away is a UPS drop-off point.

How much is a flu shot at CVS?

Flu shots in Kansas City are free at CVS to those with health insurance and through Medicare Part B. For customers without medical insurance or Medicare, it costs $73.99 for a senior dose vaccine, or $40.99 - $73.99 for a seasonal vaccine. Main Street CVS Pharmacy administers flu shots to keep you healthy and on your feet.

Does CVS accept EBT?

Yes, the Main Street CVS Pharmacy accepts EBT. Buy food at this location with your Kansas City SNAP EBT card.

Does Main Street CVS Pharmacy develop photos?

Yes, get your photos developed in Kansas City at the Main Street CVS Pharmacy. This location develops all types of film, disposable cameras, and negatives on high-quality photo paper. Processing 35mm film or a disposable camera takes between 7 and 10 days, and processing slides, 110 film, black and white film, or APS takes approximately 3 weeks.

Does CVS at 921 Main Street Kansas City, MO 64105 offer flu shots?

Flu shots are offered at the CVS Pharmacy at 921 Main Street Kansas City, MO 64105.

Schedule your flu shot ahead of time so you can get in and out faster. Provide your insurance information and answer questions online ahead of time. Shop cold and flu and stay prepared this cold and flu season with immunity support products and more.