Running errands in the city isn’t always glamorous or hassle-free. However, at 420 Fifth Avenue, we do all we can to help your day run smoothly. Whether you sign in to your personal CVS.com account to manage your automatic refills, transfer prescriptions through our mobile app or come into the drug store in person to shop our or take advantage of ExtraCare® rewards, we’ll do our best to streamline your experience.

No matter if you work, play or vacation in Midtown, it’s easy to find our CVS Pharmacy® on Fifth Avenue between 37th and 38th Streets. Maybe you’re spending time on the Bryant Park lawn over your lunch hour, hanging out with family or exploring Manhattan in the summer. Have you been ice skating at the Winter Village or doing research at the New York Public Library? Are you tired from a day of shopping on Fifth Avenue and looking for a place to quickly pick up a few essentials? In any case, our is located within easy walking distance of Bryant Park.

If you’re in the area and need your annual flu shot, stop in during pharmacy hours to take advantage of our flu shot clinic. Speaking of shots, we offer several types of immunizations for adolescents, adults and seniors. Some may require an appointment.

If you’ve ever needed something in the middle of the night and wondered, “Where is there an open ?” you know what a lifesaver it is to have a 24-hour drug store in the neighborhood. Whether you’re looking for something over-the-counter, a quick snack or a passport photo, we’re here when you need us.

Our mobile app’s features let you do so many things from the comfort of wherever you are, anytime: you can request refills, use our handy pill identifier or check drug costs and interactions. Then, when you’re ready, stop in at the pharmacy during open hours and pick up your prescriptions.

Our full-service retail location offers more than medical- and health-related items. In addition to everything you’d expect to find in a drug store, we have photo printing services so that you can create a quick, personalized gift for yourself or someone else. Use your custom prints to make a professional-looking calendar or a photo book to remember your special occasion. We also offer passport photos that conform to government regulations, so you can stop worrying about getting all those dimensions right with a selfie stick.

We keep our location well-stocked with snacks, drinks and pantry items, which may save you a trip to the grocery store. If it’s cosmetics or personal care items you’re looking for, don’t worry; we’ve got a great selection of those, too!

Please stop in anytime to pick up a few things, manage a prescription or speak with a friendly pharmacist. You can also call us at if you have any questions or for walking, driving or public transportation directions to our store.

are offered at the CVS Pharmacy at 420 Fifth Ave New York, NY 10018.

Schedule your flu shot ahead of time so you can get in and out faster. Provide your insurance information and answer questions online ahead of time. Shop cold and flu and stay prepared this cold and flu season with immunity support products and more.

Offering extra flexibility, convenience, and safety to all your packaging and shipment needs, our CVS store is now an active UPS Access Point. Drop-off and pick up your packages with UPS tracking available, so you can be sure it’s arrived. We’ll hold packages for up to 7 days, so you can pick them up on your schedule. For UPS package drop-offs, we accept pre-labeled, prepaid packages for 5 to 7 day ground and air delivery. UPS will collect all packages within 24 hours.

Find more UPS Access Point information for packages that may not qualify for shipment from our location.