Clinic details at the walk-in medical clinic Inside CVS Pharmacy at:

2001 Colonial Avenue Roanoke, VA 24015

MinuteClinic hours:

  • Friday: Opens at 8:30am Closes at 1:30pm and Opens at 2:30pm Closes at 7:00pm
  • Saturday: Opens at 9:00am Closes at 1:00pm and Opens at 1:30pm Closes at 5:30pm
  • Sunday: Opens at 9:00am Closes at 1:00pm and Opens at 1:30pm Closes at 4:30pm
  • Monday: Opens at 8:30am Closes at 1:30pm and Opens at 2:30pm Closes at 7:00pm
  • Tuesday: Opens at 8:30am Closes at 1:30pm and Opens at 2:30pm Closes at 7:00pm
  • Wednesday: Opens at 8:30am Closes at 1:30pm and Opens at 2:30pm Closes at 7:00pm
  • Thursday: Opens at 8:30am Closes at 1:30pm and Opens at 2:30pm Closes at 7:00pm
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MinuteClinic® Inside CVS Pharmacy® at 2001 Colonial Avenue, Roanoke, Virginia 24015

Located just south of the Roanoke River, our MinuteClinic® at 2001 Colonial Ave is open seven days a week, providing more than 125 services to help you and your family stay as healthy as possible. We are near the Brandon Ave SW overpass and Route 220. The Rivers Edge Sports Complex, Towers Shopping Center and Virginia Tech Carillion School of Medicine are nearby. Visit our clinic when it’s time for seasonal flu shots, physicals for school, sports or work and to receive treatment for routine illness and injuries. We proudly service several neighborhoods including Wasena, Pleasant Valley and Old Southwest.

Health care for chronic conditions

Are health issues such as diabetes, high cholesterol and high blood pressure common in your family? We can screen for these conditions to see if they are affecting your health and help you manage them before they become medical problems. Visit our clinic inside CVS Pharmacy® and talk with our on-staff practitioners about your medical history and any concerns you have. We can conduct a comprehensive health screening and risk assessment which can identify potential issues.

  • Blood pressure check
  • Cholesterol test
  • Glucose screening
  • Current health and weight assessment
  • A1c test

If you have been diagnosed with any of these chronic conditions and have difficulty managing them between appointments with your primary care doctor, we can monitor your status and provide tips to help you keep your numbers where they need to be.

Relief is just a tap away

If you or your child woke up vomiting and feverish in the middle of the night, you might want reassurance that it is a common illness. Getting dressed and going to the Emergency Room can be challenging and expensive. Are your usual products for seasonal allergies ineffective this year? Did you twist your ankle while hiking? Sign in to our app and tap Virtual Care to initiate a video visit with an experienced health care provider day or night, no matter where you are. After an initial assessment and review of the patient health history, they provide treatment plans for many common issues:

  • Strep and sore throats
  • Joint pain
  • Seasonal allergies
  • Bronchitis
  • Sinus infections
  • Muscle strains and sprains
  • Colds and flu
  • Earaches
  • UTIs and bladder infections

In addition to providing recommendations for over-the-counter products, they can also prescribe if medically necessary.

Updated seasonal flu shots

A flu shot can protect your family against the latest strains of the virus. Make an appointment or sign in at the electronic kiosk when you visit the walk-in clinic near me. We can vaccinate your whole family, 2 years and older in one trip. We can administer the multi-dose vaccine to children between 18 months and 9 years old. There are two injections required, approximately one month apart. The standard dose is suitable for adolescents, teens and adults. For seniors 65 and older and those with weakened immune systems, we can provide the high-dose vaccine.


Our weekend and evening hours make it easier to get the health care you and your family need to stay healthy throughout the year. We accept most insurance, credit cards and cash. Call us at 1-866-389-2727 for more information about our services, hours and location.


A MinuteClinic visit costs an average of 40% less than urgent care.
Source: Urgent Care Association. "2017 Benchmark Report."