CVS Pharmacy at 5644 Mission Center Road, Friars Mission Center Shopping Center San Diego, CA 92108

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Store & Photo Hours

  • M-F Open 24 hours
  • Sat Open 24 Hours
  • Sun Open 24 Hours

Pharmacy Hours

  • Mo Tu We Fr 8:00 AM - 9:00 PM
  • Th 9:00 AM - 2:00 PM
  • Sat 9:00 AM - 6:00 PM
  • Sun 10:00 AM - 6:00 PM


  • M-F 8:00 AM - 7:00 PM
  • Sat 9:00 AM - 5:30 PM
  • Sun 9:00 AM - 5:30 PM
  • Practitioners take a required lunch break. Times vary. View Hours and Services

What services does this CVS offer?

About this Pharmacy & Drug Store


Welcome to our 24-hour CVS Pharmacy® in the Friars Mission Shopping Center at the intersection of Friars Road and Frazee Road, just off Route 163. We are convenient to Mission Valley, Mission Valley East and Fashion Walk Condos. Come into our pharmacy for fast, convenient service and competitive prices on the household and beauty brands you use every day. We accept the SNAP EBT, so you can pick up healthy snacks and grocery staples that meet program guidelines while you are here.


Visit MinuteClinic® for everyday healthcare


Life happens. Bumps and bruises, colds and headaches and generally feeling under the weather. Getting a doctor’s appointment may take days, and an emergency room visit can be expensive. Stop by our walk-in clinic for quality healthcare without the long wait. We accept most insurance plans, cash and credit cards. Use the app or go online to check the wait time or schedule an appointment if that is preferred.


Our physician’s assistants and nurse practitioners can treat illness and injuries as well as provide wellness monitoring for chronic conditions, vaccinations and physicals. We offer services for adults and children 18 months and older. Ask for information about scheduling a flu clinic at your community center or workplace. The pharmacists come to you, and the only costs are for supplies and administration.


Manage medications for the entire family


Getting everything done during the day can be challenging, and long waits at the pharmacy often don’t fit. Download the app and turn on prescription access to manage medicines quickly and easily with our mobile prescription services. If there are medications that must be filled each month, set up automatic refills with notifications. For new medicines, request that information about side-effects, interactions and ingredients be emailed to you. Are you planning a trip? Print current prescriptions, so they are available in an emergency.


Browse our aisles for your favorite brands


From allergy remedies and cough medicines to skincare and cosmetics, we have the brands you love. Check out our weekly ad for buy 1, get 1 promotions and download manufacturer’s coupons to your ExtraCare® rewards card so that you never miss out on the savings. Create a personal CVS account and link your card for more opportunities to save. Get ExtraBucks® every time you use your card for 2% back on future purchases. Our drug store carries first aid supplies, sunburn relief and personal care items from companies you trust.


Online shop for more savings


Shop for online-only sales and promotions. Are there products you use every day? Add these to your easy reorder list and have them shipped to you on a regular basis, so you never run out. Upload your favorite digital images and select photo printing for in-store pickup. Add them to a project folder and build beautiful one-of-a-kind invitations, banners and save the date cards. Choose from glass, canvas or metal and turn a fun photo into unique wall or tabletop art.


Our CVS Pharmacy® is here to make your life easier. Stock up on cosmetics, update your passport photo and pick up cards and last minute gift items all in one location. Call us at 619-298-3655 for more information about our products and services or to speak with a pharmacist.


Pick up and drop off UPS® packages

Offering extra flexibility, convenience, and safety to all your packaging and shipment needs, our CVS store is now an active UPS Access Point. Drop-off and pick up your packages with UPS tracking available, so you can be sure it’s arrived. We’ll hold packages for up to 7 days, so you can pick them up on your schedule. For UPS package drop-offs, we accept pre-labeled, prepaid packages for 5 to 7 day ground and air delivery. UPS will collect all packages within 24 hours. Find more UPS Access Point information for packages that may not qualify for shipment from our location.