Store ID: #1845


Get directions (978) 658-3377

Today's hours

  • Store & Photo: Open 24 hours
  • Pharmacy: Open , closes at 10:00 PM
  • MinuteClinic®: Open , closes at 7:00 PM
  • Pharmacy closes for lunch from 1:30 PM to 2:00 PM

In-store services:

Store hours

  1. Today - Open Open 24 Hours
    Fri., Jun. 9
  2. Saturday Open 24 Hours
    Jun. 10
  3. Sunday Open 24 Hours
    Jun. 11
  4. Monday Open 24 Hours
    Jun. 12
  5. Tuesday Open 24 Hours
    Jun. 13
  6. Wednesday Open 24 Hours
    Jun. 14
  7. Thursday Open 24 Hours
    Jun. 15
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Pharmacy hours

  1. Pharmacy closes for lunch from 1:30 PM to 2:00 PM
  2. Today - Open 8:00 AM to 10:00 PM
    Fri., Jun. 9
  3. Saturday 8:00 AM to 7:00 PM
    Jun. 10
  4. Sunday 8:00 AM to 7:00 PM
    Jun. 11
  5. Monday 8:00 AM to 10:00 PM
    Jun. 12
  6. Tuesday 8:00 AM to 10:00 PM
    Jun. 13
  7. Wednesday 8:00 AM to 10:00 PM
    Jun. 14
  8. Thursday 8:00 AM to 10:00 PM
    Jun. 15
Manage Prescriptions

MinuteClinic hours

  1. Today - Open 8:00 AM to 7:00 PM
    Fri., Jun. 9
  2. Saturday 9:00 AM to 5:30 PM
    Jun. 10
  3. Sunday 9:00 AM to 4:30 PM
    Jun. 11
  4. Monday 8:00 AM to 7:00 PM
    Jun. 12
  5. Tuesday 8:00 AM to 7:00 PM
    Jun. 13
  6. Wednesday 8:00 AM to 7:00 PM
    Jun. 14
  7. Thursday 8:00 AM to 7:00 PM
    Jun. 15
Plan a visit

Nearby stores

2.5 miles

210 Ballardvale St
Wilmington, MA, 01887

2.6 miles

1900 Main St,, Oakdale Mall
Tewksbury, MA, 01876

3.2 miles

242 Cambridge St.
Burlington, MA, 01803

Discover our services at 222 Main St.


In-person and virtual care 7 days a week


Create photo cards, books, gifts, and canvas prints

About this pharmacy & drug store

The CVS Pharmacy at 222 Main Street is a Wilmington pharmacy that provides easy access to household supplies and quick pick-me-ups. The Main Street store is a one-stop shop for first aid supplies, vitamins, cosmetics, and groceries. Its easy-to-access location has made this Wilmington pharmacy a neighborhood favorite.

On top of a diverse array of food, healthcare, and more goods, the nearby Wilmington CVS Pharmacy is where you can find impressive deals. Register for an ExtraCareÆ Membership to gain access to special email offers, individualized coupons, sales notifications, and to begin earning ExtraCareÆ Rewards on select items.

Main Street CVS Pharmacy is a proud vital piece of the Wilmington city. We're ready to support all our neighbors searching for a spot to purchase everyday products hassle-free. This Wilmington CVS Pharmacy has a drive-thru pharmacy so you can get much-needed prescription refills without having to leave your car.

You can also shop for vitamins, cosmetics, personal care items, and more all day long at this 24-hour location. Stocking up on everyday products is a piece of cake.

This CVS Pharmacy is a convenient place to pick up prescription medicine, groceries, and more in Wilmington. Purchase all your daily items without leaving the comfortable confines of your neighborhood. The Across From 207 Main transit station is only a short walk from the Main Street CVS Pharmacy, so even if you don't have access to a ride you can still get what you need. All you have to do is hop on and off to shop, and hop back on to return home.

Does CVS at 222 Main St. Wilmington, MA 01887 sell hearing aids?

Yes, CVS at 222 Main St. in Wilmington, MA has . Shop our selection of OTC hearing aids from Go Hearing and Lexie Hearing (powered by Bose).

Is Main Street CVS Pharmacy a UPS Access Point?

No, UPS pickup and drop-off in Wilmington is not offered at Main Street CVS Pharmacy, but Main Street CVS Pharmacy located about 3 miles away is a UPS access point.

What does a flu shot cost at CVS?

Flu shots in Wilmington are free at CVS to those with health insurance or through Medicare Part B. If you don't have medical insurance or Medicare, you'll be charged $73.99 for a senior dose vaccine, or $40.99 - $73.99 for a seasonal vaccine. Main Street CVS Pharmacy offers flu shots to keep you healthy and on your feet.

Does CVS accept EBT?

Yes, the Main Street CVS Pharmacy accepts EBT. Use your Wilmington SNAP EBT card at this store to buy food.

Does Main Street CVS Pharmacy do photo developing?

Yes, the Main Street CVS Pharmacy is the place to go to order photo prints in Wilmington. This location develops all types of film, negatives, and disposable cameras on high-quality photo paper. Developing 35mm film or a disposable camera takes 7-10 days, while processing APS, black and white film, slides, or 110 film takes approximately 3 weeks.

What is CVS HealthHUB on 222 Main St. in Wilmington, MA?

A new health care experience at select CVS Pharmacy locations, CVS HealthHUB is staffed with a team of care professionals. HealthHUB locations offer a wide array of health care services, a and an expanded selection of wellness and health products, plus a care concierge to help you every step of the way.

What services does the CVS HealthHUB in Wilmington, MA offer?

Our MinuteClinic® providers specialize in everyday care, from coughs, colds, and ear infections, to care for chronic conditions, like sleep apnea* and . Additional services include blood pressure monitoring, , and cholesterol testing. Get high-quality care from our board-certified and today.

Are there different products available at CVS HealthHUB than what’s available at a typical CVS Pharmacy?

HealthHUB locations offer expanded health and wellness products, from nutrition and to durable medical equipment and other .


FOR SLEEP APNEA: Sleep apnea screening performed by a MinuteClinic nurse practitioner or physician assistant. If appropriate, your MinuteClinic provider may prescribe a home sleep test to be provided by an independent third-party provider.

FOR HEALTH SERVICES: Services vary by location. See store for details. Pharmacy services provided by CVS Pharmacy, Inc. Clinical services provided by a MinuteClinic nurse practitioner or physician assistant within a HealthHUB location.