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CVS Pharmacy

Store ID: #3203


Get directions (864) 370-4848

Today's hours

  • Store & Photo: Closed , opens at 7:00 AM
  • Pharmacy: Closed , opens at 9:00 AM
  • Pharmacy closes for lunch from 1:30 PM to 2:00 PM

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Store hours

  1. Today - Closed 7:00 AM to 11:00 PM
    Tue., Dec. 5
  2. Wednesday 7:00 AM to 11:00 PM
    Dec. 6
  3. Thursday 7:00 AM to 11:00 PM
    Dec. 7
  4. Friday 7:00 AM to 11:00 PM
    Dec. 8
  5. Saturday 7:00 AM to 11:00 PM
    Dec. 9
  6. Sunday 7:00 AM to 11:00 PM
    Dec. 10
  7. Monday 7:00 AM to 11:00 PM
    Dec. 11
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Pharmacy hours

  1. Pharmacy closes for lunch from 1:30 PM to 2:00 PM
  2. Today - Closed 9:00 AM to 7:00 PM
    Tue., Dec. 5
  3. Wednesday 9:00 AM to 7:00 PM
    Dec. 6
  4. Thursday 9:00 AM to 7:00 PM
    Dec. 7
  5. Friday 9:00 AM to 7:00 PM
    Dec. 8
  6. Saturday 10:00 AM to 6:00 PM
    Dec. 9
  7. Sunday 11:00 AM to 5:00 PM
    Dec. 10
  8. Monday 9:00 AM to 7:00 PM
    Dec. 11
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Nearby stores

1.8 miles

2100 Augusta St.
Greenville, SC, 29605

2.1 miles

718 Mills Avenue
Greenville, SC, 29605

2.7 miles

2401 E North St
Greenville, SC, 29615

Discover our services at 35 South Main Street


Create photo cards, books, gifts, and canvas prints

About this pharmacy & drug store

Your neighborhood CVS Pharmacy, found at 35 S.Main Street, can be found in the center of town, providing easy access to quick pick-me-ups and household items in Greenville. The S.Main Street store offers grocery goods, prescription refills, beauty products, and first aid and healthcare necessities all at one convenient stop.

Along with a diverse array of food, healthcare, and different essentials, the neighborhood Greenville CVS Pharmacy is where you can score great prices. Sign up for an ExtraCare® Membership to get personalized coupons, sales notifications, member email offers, and to start accumulating ExtraCare® Rewards on qualified items.

S.Main Street CVS Pharmacy is glad to be part of the Greenville community. We're ready to help all our neighbors searching for a spot where they can buy everyday products without extra effort. This Greenville CVS Pharmacy includes a drive-thru pharmacy to meet your prescription needs without having to leave your car.

You can buy cosmetics, personal care items, vitamins, and various other products in a well-organized store that will let you get on with the rest of your day quickly and easily. Buying the essential goods you need couldn't be easier.

This CVS Pharmacy is the place to get groceries and prescription medicine in Greenville. Pick up everything you'll need for the week without leaving the comfortable confines of your neighborhood. If you can't get a ride or don't have a car, no problem. The S.Main Street CVS Pharmacy is an easy distance from the S Main St & W McBee Ave transit station, only 0.04 miles away. All you have to do is pay the fare and you'll be dropped off nearby.

Is S.Main Street CVS Pharmacy a UPS Access Point??

Yes, a UPS Access Point is available at this CVS Pharmacy. We will keep packages addressed to you for as long as seven days. To send mail, you can drop off labeled and prepaid packages for UPS to take out for delivery within 24 hours.

How much is a flu shot at CVS?

Flu shots in Greenville are free at CVS if you have health insurance or through Medicare Part B. Without Medicare or medical insurance you'll be charged $106.99 for a senior dose vaccine, or $62.99 - $106.99 for a seasonal vaccine. S.Main Street CVS Pharmacy has flu shots to help you get through the season.

Does CVS accept EBT?

Yes, the S.Main Street CVS Pharmacy accepts the SNAP EBT card. Use your Greenville SNAP EBT card at this store to buy food.

Does S.Main Street CVS Pharmacy do photo developing?

Yes, you can order photo prints in Greenville at the S.Main Street CVS Pharmacy. We develop all types of film, negatives, and disposable cameras on high-quality photo paper. Developing a disposable camera or 35mm film takes between 7 and 10 days, while processing black and white film, APS, 110 film, or slides takes around 3 weeks.

Does CVS at 35 South Main Street Greenville, SC 29601 test for coronavirus (COVID-19)?

CVS Health is conducting coronavirus testing (COVID-19) at 35 South Main Street Greenville, SC. Patients are required to schedule an appointment for in advance. Limited appointments are available to qualifying patients due to high demand. Test types vary by location and will be confirmed during the scheduling process. Patients must bring their insurance card and proof of identity*. Please view our other for more information. Also, find for sale online and in-store.

*Insurance is not required at community testing locations.

Pick up and drop off UPS® packages

Offering extra flexibility, convenience, and safety to all your packaging and shipment needs, our CVS store is now an active UPS Access Point. Drop-off and pick up your packages with UPS tracking available, so you can be sure it’s arrived. We’ll hold packages for up to 7 days, so you can pick them up on your schedule. For UPS package drop-offs, we accept pre-labeled, prepaid packages for 5 to 7 day ground and air delivery. UPS will collect all packages within 24 hours.

Find more UPS Access Point information for packages that may not qualify for shipment from our location.